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Endorphins and Naltrexone... SIZE matters!

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size does indeed matter. this a repeat, but:

see also Crain and Shen in

http://www.drugabuse.gov/pdf/monographs/147.pdf

''In addition, 10 fM beta-endorphin elicits

marked naloxone-reversible enhancement of the cytotoxic " natural

killer "

cell activity of human blood cells (see figure 1; dose-response curve

in

Mathews et al. 1983).''

fM is femto-Molar! this is 10^-15 of a Mole, I think...

Don't worry, I'm not reading that because I want to abuse any drugs.

I was just trying to find a free copy of Crain and Shen's paper.

-Sullivan

--- In low dose naltrexone , " maxbtm " <maxbtm@y...>

wrote:

> Another interesting reading about Naltrexone regulating Endorphins

> levels.

>

> http://www.ibis.sfu.ca/~rhlogan/todd.html

>

> Ciao

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One person has complained that they can't access this document.

It is very large (it is a monograph in pdf format containing

many papers). At dialup speed it will take a *very* long time.

In Adobe Acrobat I have had a problem which causes the machine to

appear to lock up. The workaround I have found is to either

reboot and open the pdf before opening any *other* pdf files,

*or* to use the three fingered salute to " end task " any lingering

instances of Acrobat which might be there, and " end task " any

frozen http instances.

If you allow me to send a pdf attachment I'll try to include only

that document in a private email to you, or failing that, the whole

enchilada (it's the second last paper, of course).

-Sullivan

> > Another interesting reading about Naltrexone regulating

Endorphins

> > levels.

> >

> > http://www.ibis.sfu.ca/~rhlogan/todd.html

> >

> > Ciao

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