Guest guest Posted September 19, 2003 Report Share Posted September 19, 2003 " The bacterial protein stimulates an immune system regulator which dampens down the body's immune response. " It seems that its function is to suppress chronic inflammatory disease, " said Dr . The regulator was able to shut down the arthritic inflammation being produced by the immune system. " - irish times article !!! This is probably the same one that is stimulated by naltrexone, and suppressed by interferon! You know, the one that makes memory helper T cells die before they can do any damage? Holy spirits preserve us! I sure hope that one reaches the market before I die. Meantime I'm gonna take naltrexone. >LDN(Low Dose Naltrexone) has regulated my sleep. I'm no longer >needing a sleep aid. I fall asleep very easily now and sleep >like a baby and get up refreshed. I've been a severe insomniac >for many years. In the early years with MS all I could do was sleep, >I couldn't seem to wake up. It was as though I was slipping into a >coma. As the disease progressed my sleep habits changed to being >awake for 2 or 3 days straight without blinking an eye. Sleep >just simply would not come. I've been using a sleep aid for about >12 years. December 2003 I will have been diagnosed with MS 14 years. >What do I want for Christmas? An 18 wheeler load of LDN!! I also >want a bicycle. That supports the endocrine circadian pendulum theory. The melatonin your body normally produces should be enough. So should the endorphins. But if your endogenous, circadian pattern is delayed, random or absent, as it is in many diseases, you may not produce enough of these to do those jobs they are supposed to do, like wake you up and make you sleepy. You will get sleep deprivation, or as you point out, waking deprivation. The thing becomes self-perpetuating. It is probable that taking it at the same time every day is at least as important as the dose. The pendulum push may happen at 1, 2, or 3 mg./day. But if it is taken regularly it will be most effective at pushing the pendulum at the right time. Secondary to that would be the circadian wall-clock time at which the push occurs. And since one daily cycle is reestablished (beta endorphin) so are they all, since one pituitary clock controls them all. Eating may be a secondary trigger for a clock that is slaved to the main one. They found that in mice. I also got my sleep fixed when I was in rehab. Regular mealtimes, exercise times, and the long summer light all combined, and I haven't missed a night's sleep since. Glad you have conquered this one too and keep taking it at the same time every day! I'd better go to bed :-) -Sullivan P.S. I feel a *heck* of a lot better since I dropped Avonex. Wheeee! Quote Link to comment Share on other sites More sharing options...
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