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Hi

> I read that

>

> " If a person moves from a high-risk area to a lower risk area prior

> to the age of 15, then that person will assume the risk of

developing

> MS of the more southern latitude region. However, once MS has

> developed, changing location has no consequence on the course of

the

> disease. "

Yep, that's what they say <grin>

>

> (I think this is backwards: people don't generally move to a hotter

> climate once they have developed a problem with sensitivity to heat.

> But you can assume the risk of a more northern region by moving

> North. I bet you can do that at any age.)

>

It's funny.. For years (!) I had incredible sensitivity to the cold of

winter in N.E. New York (brrr), and even in the somewhat mild summers

there - I felt like I was drunk if I went out in the heat... then

about 8 years ago or so, we had to move down south-er (Kentucky).. I

did better there with the heat the entire time I was there even though

it was about 10 degrees hotter in general, and also did better with

the cold there as well.. very weird I thought .. More Vitamin D year

round maybe (BIG open skys?) Well, we're back in NY now - it's been

about a year and a half, and so far the differences in temperatures

between seasons hasn't hit me as in those early years.. so far so

good.. but I'm am darn sure gonna coninue take Vit. D supplements

<grin>

> Is this because the older you get the harder it is to overcome the

> effect of your prenatal training? And the older you get the less

> endorphin you secrete? What effect does age have on your endorphin

> clock (how loud it ticks)?

I'm hoping the LDN is going to counter the effects of moving back

here.. and who knows... maybe the levels of endorphins are affected by

age.. if so, I started this at a good time I would expect.

Take care,

Janis

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Welcome Denny,

Throw out the Avonex and solumedrol...I did...and if you are having

exacerbatioins while on *A* then it's not working for you. I am so

glad that you are giving LDN a try.

My good wishes for your success.

Sally

> Hi all,

> I've been reading posts on this page for sometime now,

> and will like to share my experience if you don't

> mind.

> I moved to the US from Nigeria,(a low risk part of the

> world for MS) com

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What I am suggesting is that it is the variation in day-length which is

greater the farther you are from the equator. And the speed of that

variation, for which I don't know the math.

Moving north increases the learning task, in both speed and

duration.

Being north already, means you have more adapting to do every year

than if you lived more to the south. If this day length adaptation gets

disrupted, your goose is easier to cook. See also electric light, daylight

saving time, and travel across time zones.

My major attacks have been in the spring and fall. In winter and

summer the day-length changes more gradually, until solstice when

it changes hardly at all. Flu season starts in the fall (before or

after equinox?). You may already know someone who has their fall

cold for this year.

You may be predisposed because you already had a problem

entraining your circadian endorphin. Or you may have been under

some stress which depleted your stress endorphin. And the

effect on your daily production when the days are getting more *rapidly*

longer or shorter may have put you "over the edge". These semiannual

intervals might be thought of as higher risk times. At the equinoxes and

solstices, the lengths of dark and light times actually *reverses* (longer

to shorter and vice versa. But the rapidity of this is much less at the

summer and winter changeovers (I think - anyone out there know the math?).

Your prenatal training is not directly light dependent. But it is

dependent on the day-length variation your mum is experiencing

before your birth.

The younger you are the closer to your mother's daily

endorphin lessons. It may take till age 15 or so to forget them. The

time of year you were born at may be a factor. What if MS sufferers

are predominantly gestated during the spring and fall?

Of course all this is speculation but it fits many of the facts I know.

-Sullivan

"One day we're waiting for the sky to fall."

"The next we're dazzled by the beauty of it all."

-Bruce Cockburn

----- Original Message -----

From: capp3735@...

jchrissullivan

Sent: Tuesday, September 09, 2003 3:39 PM

Subject: Re: [low dose naltrexone] and another thing...

Demographically, according to MS Research, people living north (north of where, I don't know) are more likely to develop MS. If a person moves south before the age of 15, they are less likely to get it. I was born and raised in xxxxxx. My first MS attack was when I still lived up there, at age xx, when I was x months pregnant with my son.Margie> > From: "jchrissullivan" <chris_sullivan@...>> Date: 2003/09/09 Tue AM 09:06:23 EDT> low dose naltrexone > Subject: [low dose naltrexone] and another thing...> >

I read that "If a person moves from a high-risk area to a lower risk area prior to the age of 15, then that person will assume the risk of developing MS of the more southern latitude region. However, once MS has developed, changing location has no consequence on the course of the disease."(I think this is backwards: people don't generally move to a hotter climate once they have developed a problem with sensitivity to heat.But you can assume the risk of a more northern region by moving North. I bet you can do that at any age.)Is this because the older you get the harder it is to overcome theeffect of your prenatal training? And the older you get the lessendorphin you secrete? What effect does age have on your endorphinclock (how loud it ticks)?-Sullivan "You can't teach an old clock new ticks"

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