Guest guest Posted December 23, 2003 Report Share Posted December 23, 2003 Hi mary, go to the LDN web site and it says on there that LDN doesn't work well when taken with The beta interferons but you can take Copaxone. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 > > After my last relapse my nuro insisted that I go on one of the CRAB drugs. > Having already been on Copaxone and hated the constant site reactions I went > on Avenox. Does anyone here know about taking Avenix and LDN? Is anyone in > this group taking A + LDN? > > > ========= Dr. Bob Lawrence from the UK who has MS & uses LDN himself explains why the temporary increase in MS symptoms and what drugs SHOULD NOT be used in conjunction with LDN. == When starting this LDN(Low Dose Naltrexone) therapy in the treatment of MS, there may also be some initial transient, though temporary, increase in MS symptoms. Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. These increased symptoms would not normally be expected to last more than seven to ten days. Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. This temporary increase in symptoms may also perhaps be explained when we consider the manner in which this drug is expected to work. In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. Initially, MS occurs due to a reduction in the activity of the controlling influence of the suppressor T-cells within the immune system. During an acute relapse, the overall number of T-cells is reduced, the normal balance of helper T-cells and suppressor T-cells is disrupted and the damaging helper (CD-4) T-cells tend to predominate. This is the situation most pronounced during an acute relapse but occurs similarly, but to a lesser extent, in chronic progressive MS. Under the influence of LDN there will be an expected increase in the overall numbers of T-cells but, because the CD-4, helper T-cells tend to predominate at this time, an increase in their numbers will expectedly tend to increase MS symptoms. It is only when the numbers of suppressor T-cells effectively & quot;catch up & quot; that the normal balance is restored and symptoms once again diminish and improve. Dr. M R Lawrence posted by Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 > posted by I have never used Avonex, Copaxone or any of the interferons, just steroids, baclofen, mild exercise and good diet. I stop taking steroids at least 2 weeks before getting back to LDN and experience a quite rapid 'lift' in terms of balance, strength, energy etc., but I am noticing that after eight weeks or so, the initial benefits from the LDN are beginning to fade and I am experiencing a recurrence of the old fatigue problems, foot drag and loss of strength etc. Does anyone know if I should increase the dosage from 3ml/mg after 9.00 PM or just take a rest altogether? I take my LDN by disolving half a ReVia tablet (25mg) in 25ml of distilled water. (so 3ml = 3mg). Any help/advice would be much appreciated as I still can't afford stem-cell therapy! Regards, Iain Quote Link to comment Share on other sites More sharing options...
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