Sjogrens/hashimotos - taken LDN Therapy for 4 weeks -- Results

January 11, 2008

As I promised I am sharing my results of taking LDN.

After 4 weeks of LDN for Sjogrens/Hashimotos

Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN 907

Energy levels have slowly reduced again after i felt I was getting

better, therefore I can say fatigue is reappearing.

Sleep Disturbances reappearing more often=less sleep.

I guess all one can say is damn shame, nice try !

I had expected that the hasimoto antibodies to have decreased..very

surprised to see an almost 2x increase !

My understanding of LDN was that it would decrease the unwanted

antibodies while boosting the immune system..it appears perhaps to be

boosting the antibodies at least in me...at the moment.

For the record I aim to give it another month to 2 months

trial..unless health contradicts.

Cheers

January 11, 2008

Good luck - - - you are in my prayers.Jeff [low dose naltrexone] Sjogrens/hashimotos - taken LDN Therapy for 4 weeks -- Results

As I promised I am sharing my results of taking LDN.

After 4 weeks of LDN for Sjogrens/Hashimotos

Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN 907

Energy levels have slowly reduced again after i felt I was getting

better, therefore I can say fatigue is reappearing.

Sleep Disturbances reappearing more often=less sleep.

I guess all one can say is damn shame, nice try !

I had expected that the hasimoto antibodies to have decreased..very

surprised to see an almost 2x increase !

My understanding of LDN was that it would decrease the unwanted

antibodies while boosting the immune system..it appears perhaps to be

boosting the antibodies at least in me...at the moment.

For the record I aim to give it another month to 2 months

trial..unless health contradicts.

Cheers

Never miss a thing. Make your homepage.

January 11, 2008

>

> As I promised I am sharing my results of taking LDN.

>

> After 4 weeks of LDN for Sjogrens/Hashimotos

>

> Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN

907

>

> Energy levels have slowly reduced again after i felt I was getting

> better, therefore I can say fatigue is reappearing.

> Sleep Disturbances reappearing more often=less sleep.

>

> I guess all one can say is damn shame, nice try !

>

> I had expected that the hasimoto antibodies to have decreased..very

> surprised to see an almost 2x increase !

> My understanding of LDN was that it would decrease the unwanted

> antibodies while boosting the immune system..it appears perhaps to be

> boosting the antibodies at least in me...at the moment.

>

> For the record I aim to give it another month to 2 months

> trial..unless health contradicts.

>

> Cheers

>

================

Have you ever had a live blood analysis done with a darkfield

microscope or via IGeneX Labs to check for lyme disease?

January 11, 2008

> >

> > As I promised I am sharing my results of taking LDN.

> >

> > After 4 weeks of LDN for Sjogrens/Hashimotos

> >

> > Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> > Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN

> 907

> >

> > Energy levels have slowly reduced again after i felt I was getting

> > better, therefore I can say fatigue is reappearing.

> > Sleep Disturbances reappearing more often=less sleep.

> >

> > I guess all one can say is damn shame, nice try !

> >

> > I had expected that the hasimoto antibodies to have decreased..very

> > surprised to see an almost 2x increase !

> > My understanding of LDN was that it would decrease the unwanted

> > antibodies while boosting the immune system..it appears perhaps to be

> > boosting the antibodies at least in me...at the moment.

> >

> > For the record I aim to give it another month to 2 months

> > trial..unless health contradicts.

> >

> > Cheers

> >

> ================

>

> Have you ever had a live blood analysis done with a darkfield

> microscope or via IGeneX Labs to check for lyme disease?

>

Hi

Well no I have not and will mention to my Doc next time..Lyme is rare

in Australia but not unknown...Ive got a few autoimmune markers which

is enough to make me think...that autoimmune is the right area

reflecting the symptoms I have.

Thx for your post

January 11, 2008

Just wanted to add that I am taking 4.5mg avicel filler, and also

taking probiotics daily.

Not taking any contra drugs..

Of course Im hoping to ride this out and..perhaps it will get worse

before it gets better.

Will report back in 2+ weeks

>

> As I promised I am sharing my results of taking LDN.

>

> After 4 weeks of LDN for Sjogrens/Hashimotos

>

> Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN 907

>

> Energy levels have slowly reduced again after i felt I was getting

> better, therefore I can say fatigue is reappearing.

> Sleep Disturbances reappearing more often=less sleep.

>

> I guess all one can say is damn shame, nice try !

>

> I had expected that the hasimoto antibodies to have decreased..very

> surprised to see an almost 2x increase !

> My understanding of LDN was that it would decrease the unwanted

> antibodies while boosting the immune system..it appears perhaps to be

> boosting the antibodies at least in me...at the moment.

>

> For the record I aim to give it another month to 2 months

> trial..unless health contradicts.

>

> Cheers

>

January 11, 2008

> > >

> > > As I promised I am sharing my results of taking LDN.

> > >

> > > After 4 weeks of LDN for Sjogrens/Hashimotos

> > >

> > > Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> > > Hashimotos Antibodies increasing - before LDN 640 after 4 weeks

LDN

> > 907

> > >

> > > Energy levels have slowly reduced again after i felt I was

getting

> > > better, therefore I can say fatigue is reappearing.

> > > Sleep Disturbances reappearing more often=less sleep.

> > >

> > > I guess all one can say is damn shame, nice try !

> > >

> > > I had expected that the hasimoto antibodies to have

decreased..very

> > > surprised to see an almost 2x increase !

> > > My understanding of LDN was that it would decrease the unwanted

> > > antibodies while boosting the immune system..it appears perhaps

to be

> > > boosting the antibodies at least in me...at the moment.

> > >

> > > For the record I aim to give it another month to 2 months

> > > trial..unless health contradicts.

> > >

> > > Cheers

> > >

> > ================

> >

> > Have you ever had a live blood analysis done with a darkfield

> > microscope or via IGeneX Labs to check for lyme disease?

> >

>

> Hi

>

> Well no I have not and will mention to my Doc next time..Lyme is rare

> in Australia but not unknown...Ive got a few autoimmune markers which

> is enough to make me think...that autoimmune is the right area

> reflecting the symptoms I have.

>

> Thx for your post

>

==========

If you can find a physician with a Bradford Variable Projection

Microscope to test for lyme, that'd be great and you can get your

candida yeast load checked with this microscope.

You are aware that LDN can cause a temporary increase in symptoms in

the early stages of the treatment?

January 11, 2008

> > > >

> > > > As I promised I am sharing my results of taking LDN.

> > > >

> > > > After 4 weeks of LDN for Sjogrens/Hashimotos

> > > >

> > > > Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> > > > Hashimotos Antibodies increasing - before LDN 640 after 4 weeks

> LDN

> > > 907

> > > >

> > > > Energy levels have slowly reduced again after i felt I was

> getting

> > > > better, therefore I can say fatigue is reappearing.

> > > > Sleep Disturbances reappearing more often=less sleep.

> > > >

> > > > I guess all one can say is damn shame, nice try !

> > > >

> > > > I had expected that the hasimoto antibodies to have

> decreased..very

> > > > surprised to see an almost 2x increase !

> > > > My understanding of LDN was that it would decrease the unwanted

> > > > antibodies while boosting the immune system..it appears perhaps

> to be

> > > > boosting the antibodies at least in me...at the moment.

> > > >

> > > > For the record I aim to give it another month to 2 months

> > > > trial..unless health contradicts.

> > > >

> > > > Cheers

> > > >

> > > ================

> > >

> > > Have you ever had a live blood analysis done with a darkfield

> > > microscope or via IGeneX Labs to check for lyme disease?

> > >

> >

> > Hi

> >

> > Well no I have not and will mention to my Doc next time..Lyme is rare

> > in Australia but not unknown...Ive got a few autoimmune markers which

> > is enough to make me think...that autoimmune is the right area

> > reflecting the symptoms I have.

> >

> > Thx for your post

> >

> ==========

>

> If you can find a physician with a Bradford Variable Projection

> Microscope to test for lyme, that'd be great and you can get your

> candida yeast load checked with this microscope.

>

> You are aware that LDN can cause a temporary increase in symptoms in

> the early stages of the treatment?

>

Hello

Yes I am aware that LDN can cause an increase in symptoms early on..I

still have hope..as I said I will continue with it unless my health

contradicts further.

I will look into the Bradford Variable Projection when i get a moment

from this fatigue.

Cheers

January 11, 2008

Hi, I'm sorry to hear you've had a worsening of symptoms, especially

since some of us who were hypothyroid have experienced prompt

improvement. By Hashi's antibodies I assume you mean the TPO

antibodies. If they behave like the TSH receptor antibodies involved

in Graves' disease (of which I had a hypothyroid phase), we are told

they can stay in the bloodstream for as long as 3 1/2 months, which

suggests you may need to wait longer to get an accurate count.

Best wishes,

B., hypothyroid for 2 1/2 years after taking antithyroid meds

for Graves'.

>

> As I promised I am sharing my results of taking LDN.

>

> After 4 weeks of LDN for Sjogrens/Hashimotos

>

> Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN

907

>

January 11, 2008

Just remember that antibodies live and die on a 90 day cycle. In other words,

the ABs

(which ones? TPOab?) you see now on tests are those created in Oct / Nov. You

won't

see a reflection of LDN affected ABs until March.

Since ABs are slow moving I don't even test mine more than annually. If I do an

LDN trial

I'll give it at least four months (an extra month for clarity) unless there's an

adverse

reaction.

Have you had your thyroid levels (T4, Free and T3, Free) tested? That may give

you a

picture of what's going on now.

Hope this helps.

a in NYC

Graves Disease

>

> As I promised I am sharing my results of taking LDN.

>

> After 4 weeks of LDN for Sjogrens/Hashimotos

>

> Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN 907

>

> Energy levels have slowly reduced again after i felt I was getting

> better, therefore I can say fatigue is reappearing.

> Sleep Disturbances reappearing more often=less sleep.

>

> I guess all one can say is damn shame, nice try !

>

> I had expected that the hasimoto antibodies to have decreased..very

> surprised to see an almost 2x increase !

> My understanding of LDN was that it would decrease the unwanted

> antibodies while boosting the immune system..it appears perhaps to be

> boosting the antibodies at least in me...at the moment.

>

> For the record I aim to give it another month to 2 months

> trial..unless health contradicts.

>

> Cheers

>

January 11, 2008

a,

I'm a lurker here, but I have Hashi's (not on meds yet) so I found

this post quite interesting.

I had no idea those antibodies lasted 90 days. Which makes it

difficult to know if any therapy, whether medicinal or natural, is

having a positive effect on them. I hate to think I have to stick

with something for a long time that might not even be working, yet be

unable to get an accurate lab test done to at least have some idea if

it's worth continuing.

>

> Just remember that antibodies live and die on a 90 day cycle. In

other words, the ABs

> (which ones? TPOab?) you see now on tests are those created in Oct

/ Nov. You won't

> see a reflection of LDN affected ABs until March.

>

> Since ABs are slow moving I don't even test mine more than annually.

If I do an LDN trial

> I'll give it at least four months (an extra month for clarity)

unless there's an adverse

> reaction.

>

> Have you had your thyroid levels (T4, Free and T3, Free) tested?

That may give you a

> picture of what's going on now.

>

> Hope this helps.

>

> a in NYC

> Graves Disease

>

January 11, 2008

Hi ,

For those of us who are hypothyroid due to blocking antibodies rather than

thyroid destruction, results can also be seen in a return to normal thyroid

levels, which will send you hyper if you are also taking thyroid

replacement. Since you are not, you would notice a decrease in hypothyroid

symptoms (dry hair and skin, aches, slow digestion, depression, muscle

cramps, weight gain, perhaps high cholesterol and blood pressure). Testing

thyroid levels (FT4 and FT3) should show the changes more quickly, but

remember that TSH will lag and also would need to be tested later rather

than immediately.

I also had improvement in eczema and vicious arthritis symptoms (suggesting

that I have some rheumatoid arthritis).

Best wishes,

B.

________________________________

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of b53cjf

Sent: Friday, January 11, 2008 2:59 PM

low dose naltrexone

Subject: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy for

4 weeks -- Results

a,

I'm a lurker here, but I have Hashi's (not on meds yet) so I found

this post quite interesting.

I had no idea those antibodies lasted 90 days. Which makes it

difficult to know if any therapy, whether medicinal or natural, is

having a positive effect on them. I hate to think I have to stick

with something for a long time that might not even be working, yet be

unable to get an accurate lab test done to at least have some idea if

it's worth continuing.

>

> Just remember that antibodies live and die on a 90 day cycle. In

other words, the ABs

> (which ones? TPOab?) you see now on tests are those created in Oct

/ Nov. You won't

> see a reflection of LDN affected ABs until March.

>

> Since ABs are slow moving I don't even test mine more than annually.

If I do an LDN trial

> I'll give it at least four months (an extra month for clarity)

unless there's an adverse

> reaction.

>

> Have you had your thyroid levels (T4, Free and T3, Free) tested?

That may give you a

> picture of what's going on now.

>

> Hope this helps.

>

> a in NYC

> Graves Disease

>

January 11, 2008

Hi !

Thanks for mentioning this group, by the way.

Can you explain your statement below? I'm not understanding what

exactly " will send you hyper if you are also taking thyroid meds " .

Is it due to the blocking antibodies not allowing the hormone to

attack to receptors, thereby allowing it to build up to too high

levels in the blood?

Can hashi's also have blocking antibodies?

That is wonderful that LDN seems to be working for those antibodies.

>

> Hi ,

>

> For those of us who are hypothyroid due to blocking antibodies

rather than

> thyroid destruction, results can also be seen in a return to normal

thyroid

> levels, which will send you hyper if you are also taking thyroid

> replacement. Since you are not, you would notice a decrease in

hypothyroid

> symptoms (dry hair and skin, aches, slow digestion, depression, muscle

> cramps, weight gain, perhaps high cholesterol and blood pressure).

Testing

> thyroid levels (FT4 and FT3) should show the changes more quickly, but

> remember that TSH will lag and also would need to be tested later rather

> than immediately.

>

> I also had improvement in eczema and vicious arthritis symptoms

(suggesting

> that I have some rheumatoid arthritis).

>

> Best wishes,

> B.

>

> _

January 11, 2008

Hi ,

Elaine has an article about the TSH receptor antibodies on

suite101.com that said, if I recall correctly, that 1/3 of people who are

hypothyroid have them. They block the TSH receptors and keep people from

getting adequate thyroid hormone by disrupting the feedback loop that should

keep thyroid levels correct. Since you have some TSI, I would bet you have

some of these as well.

People who are taking thyroid replacement because they are hypothyroid and

who then regain natural thyroid function will end up with too much thyroid

hormone in their system, because their body is now making what it needs plus

they are still taking more. That seems to have happened to me and a couple

of other people. I'm confident that this is what happened to me because I

was taking a medium-sized dose of thyroid replacement, had an increase in my

pulse after two weeks on LDN (often an indicator that a person is

hyperthyroid), and then had a return to normal heart rate after stopping the

thyroid replacement. And where I felt hyper during the period of elevated

pulse, I feel euthyroid now.

I'd been taking T4 and T3 since stopping PTU in 2005; I stopped them 8 days

ago and am still feeling great and euthyroid. Of course, FT4 and FT3 testing

would tell the true story, but my pulse is usually a good indicator for me

(60 is hypo, 80 is hyper, 68 is euthyroid). I also have baseline antibody

tests (TSI, TBII, TPO) and will recheck in 3-4 month--but I can " feel "

they're decreasing.

And yes, I'm so pleased that we're investigating another autoimmune disease

that LDN may help. So many of us who are hypothyroid have to beg and plead

with our doctors to keep our thyroid levels above the extreme bottom of the

range. And if it will help Graves' and thyroid eye disease, that will be

amazing.

Best wishes,

B.

________________________________

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of b53cjf

Sent: Friday, January 11, 2008 3:26 PM

low dose naltrexone

Subject: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy for

4 weeks -- Results

Hi !

Thanks for mentioning this group, by the way.

Can you explain your statement below? I'm not understanding what

exactly " will send you hyper if you are also taking thyroid meds " .

Is it due to the blocking antibodies not allowing the hormone to

attack to receptors, thereby allowing it to build up to too high

levels in the blood?

Can hashi's also have blocking antibodies?

That is wonderful that LDN seems to be working for those antibodies.

January 12, 2008

,

Thanks for the explanation, now I get it.

You really seem to know your body well, knowing which pulse rate

indicates which condition of the thyroid. I hope I get to that point,

but I have a long way to go.

I have an appt with a U of Chicago thyroid doc to get a full

evaluation of my thyroid and nodules and to see if I have other

autoimmune conditions going on. I'm going to ask her about LDN and

see if she's familiar with it.

Thanks for the info,

>

> Hi ,

>

> Elaine has an article about the TSH receptor antibodies on

> suite101.com that said, if I recall correctly, that 1/3 of people

who are

> hypothyroid have them. They block the TSH receptors and keep people from

> getting adequate thyroid hormone by disrupting the feedback loop

that should

> keep thyroid levels correct. Since you have some TSI, I would bet

you have

> some of these as well.

>

> People who are taking thyroid replacement because they are

hypothyroid and

> who then regain natural thyroid function will end up with too much

thyroid

> hormone in their system, because their body is now making what it

needs plus

> they are still taking more. That seems to have happened to me and a

couple

> of other people. I'm confident that this is what happened to me

because I

> was taking a medium-sized dose of thyroid replacement, had an

increase in my

> pulse after two weeks on LDN (often an indicator that a person is

> hyperthyroid), and then had a return to normal heart rate after

stopping the

> thyroid replacement. And where I felt hyper during the period of

elevated

> pulse, I feel euthyroid now.

>

> I'd been taking T4 and T3 since stopping PTU in 2005; I stopped them

8 days

> ago and am still feeling great and euthyroid. Of course, FT4 and FT3

testing

> would tell the true story, but my pulse is usually a good indicator

for me

> (60 is hypo, 80 is hyper, 68 is euthyroid). I also have baseline

antibody

> tests (TSI, TBII, TPO) and will recheck in 3-4 month--but I can " feel "

> they're decreasing.

>

> And yes, I'm so pleased that we're investigating another autoimmune

disease

> that LDN may help. So many of us who are hypothyroid have to beg and

plead

> with our doctors to keep our thyroid levels above the extreme bottom

of the

> range. And if it will help Graves' and thyroid eye disease, that will be

> amazing.

>

> Best wishes,

> B.

> ________________________________

>

January 12, 2008

> >

> > As I promised I am sharing my results of taking LDN.

> >

> > After 4 weeks of LDN for Sjogrens/Hashimotos

> >

> > Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

> > Hashimotos Antibodies increasing - before LDN 640 after 4 weeks LDN

> 907

> >

>

Hi

Please dont be sorry for me ..Ive been searching about antibody

lifecycle but not much luck have you a link..quite interested in

learning more.

The hashimotos is one thing, personally for me the Sjogrens is the one

I really hoped would ease..but as I say I will give it a bit longer.

Thanks for posting

January 12, 2008

Hi ,

Having nodules complicates matters, though if your thyroid levels are too

low they will grow, and probably should shrink if you get your levels up to

your set point in the range.

Since my Graves' dx 5 1/2 years ago I've learned a lot about " my body on

thyroid hormone, " but the biggest lesson I've learned is that lab work is

the only reliable way to know for sure. I now gain weight when I'm hyper

rather than lose it, as a case in point.

Good luck with your thyroid doc. Keep in mind that some ANA markers will be

positive in thyroid disease and don't necessarily mean other conditions.

Hopefully if you bring some info on LDN she will learn about if even if

she's not already knowledgeable.

best wishes,

B.

__________

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of b53cjf

Sent: Saturday, January 12, 2008 12:19 AM

low dose naltrexone

Subject: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy for

4 weeks -- Results

,

Thanks for the explanation, now I get it.

You really seem to know your body well, knowing which pulse rate

indicates which condition of the thyroid. I hope I get to that point,

but I have a long way to go.

I have an appt with a U of Chicago thyroid doc to get a full

evaluation of my thyroid and nodules and to see if I have other

autoimmune conditions going on. I'm going to ask her about LDN and

see if she's familiar with it.

Thanks for the info,

January 14, 2008

As far as ranges of TSH. You might refer your doctors to the current American Association of clinical Endocrinologists TSH to be between .3-3.0 That was changed two years ago, but they have not informed everyone. The average american without thyroid disease has a TSH of 1.5 , so we should shoot for that.

-------------- Original message -------------- From: "b53cjf" <b53cjf@...>

,Thanks for the explanation, now I get it.You really seem to know your body well, knowing which pulse rateindicates which condition of the thyroid. I hope I get to that point,but I have a long way to go.I have an appt with a U of Chicago thyroid doc to get a fullevaluation of my thyroid and nodules and to see if I have otherautoimmune conditions going on. I'm going to ask her about LDN andsee if she's familiar with it.Thanks for the info,>> Hi ,> > Elaine has an article about the TSH receptor antibodies on> suite101.com that said, if I recall correctly, that 1/3 of peoplewho are> hypothyroid have them. They block the TSH receptors and keep people from> getting adequate thyroid hormone by disrupting the feedback loopthat should> keep thyroid levels correct. Since you have some TSI, I would betyou have> some of these as well.> > People who are taking thyroid replacement because they arehypothyroid and> who then regain natural thyroid function will end up with too muchthyroid> hormone in their system, because their body is now making what itneeds plus> they are still taking more. That seems to have happened to me and acouple> of other people. I'm confident that this is what happened to mebecause I> was taking a medium-sized dose of thyroid replacement, had anincrease in my> pulse after two weeks on LDN (often an indicator that a person is> hyperthyroid), and then had a return to normal heart rate afterstopping the> thyroid replacement. And where I felt hyper during the period ofelevated> pulse, I feel euthyroid now.> &gt

; I'd been taking T4 and T3 since stopping PTU in 2005; I stopped them8 days> ago and am still feeling great and euthyroid. Of course, FT4 and FT3testing> would tell the true story, but my pulse is usually a good indicatorfor me> (60 is hypo, 80 is hyper, 68 is euthyroid). I also have baselineantibody> tests (TSI, TBII, TPO) and will recheck in 3-4 month--but I can "feel"> they're decreasing.> > And yes, I'm so pleased that we're investigating another autoimmunedisease> that LDN may help. So many of us who are hypothyroid have to beg andplead> with our doctors to keep our thyroid levels above the extreme bottomof the> range. And if it will help Graves' and thyroid eye disease, that will be> amazing.> > Best wishes,> B.> ________________________________>

January 14, 2008

there have been several studies that selenium can reduce antibodies also. You would take about 200 mcg per day.. You could google thyroid antibodies and selenium.

-------------- Original message -------------- From: "croma_clear1" <jlcandrb@...>

> > > >> > > > As I promised I am sharing my results of taking LDN.> > > > > > > > After 4 weeks of LDN for Sjogrens/Hashimotos> > > > > > > > Sjogrens Dryness - Skin/Eyes/Mouth has noticeably worsened

BR>> > > > Hashimotos Antibodies increasing - before LDN 640 after 4 weeks > LDN > > > 907> > > > > > > > Energy levels have slowly reduced again after i felt I was > getting> > > > better, therefore I can say fatigue is reappearing.> > > > Sleep Disturbances reappearing more often=less sleep.> > > > > > > > I guess all one can say is damn shame, nice try !> > > > > > > > I had expected that the hasimoto antibodies to have > decreased..very> > > > surprised to see an almost 2x increase !> > > > My understanding of LDN was that it would decrease the unwanted> > > > antibodies while boosting the immune system..it appears perhaps > to be> > > > boosting the antibodies at least in me...at the moment.> > > > > > > &gt

; For the record I aim to give it another month to 2 months> > > > trial..unless health contradicts.> > > > > > > > Cheers> > > >> > > ================> > > > > > Have you ever had a live blood analysis done with a darkfield > > > microscope or via IGeneX Labs to check for lyme disease?> > > > > > > > >> > > > Hi > > > > Well no I have not and will mention to my Doc next time..Lyme is rare> > in Australia but not unknown...Ive got a few autoimmune markers which> > is enough to make me think...that autoimmune is the right area> > reflecting the symptoms I have.> > > > Thx for your post> >> ==========> > If you can find a physician with a Bradford Variable Projection > Microscope to test f

or lyme, that'd be great and you can get your > candida yeast load checked with this microscope.> > You are aware that LDN can cause a temporary increase in symptoms in > the early stages of the treatment?> > >Hello Yes I am aware that LDN can cause an increase in symptoms early on..Istill have hope..as I said I will continue with it unless my healthcontradicts further.I will look into the Bradford Variable Projection when i get a momentfrom this fatigue.CheersCheers

January 14, 2008

An additional problem with TSH is that those of us with TSH receptor

antibodies (Graves' and some Hashimotos) will have an artificially low TSH,

meaning that only the FT3 and FT4 truly indicated our thyroid levels.

And yes, doctors are still telling folks with a TSH of 4.5 that they're just

fine and any symptoms stemming from this metabolic slowdown are " not from

their thyroid. "

Best wishes,

B.

________________________________

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of paulbatt@...

Sent: Monday, January 14, 2008 12:45 AM

low dose naltrexone

Subject: Re: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy

for 4 weeks -- Results

As far as ranges of TSH. You might refer your doctors to the current

American Association of clinical Endocrinologists TSH to be between .3-3.0

That was changed two years ago, but they have not informed everyone. The

average american without thyroid disease has a TSH of 1.5 , so we should

shoot for that.

January 14, 2008

I'm new to this list and have Hashimoto's. I am medicated and my TSH is usually very low but my FT3 and FT4 hover around the bottom end of the range - and upping meds just makes me very symptomatic. Any small change in meds or homones (especially estrogen hormone levels) really affects me and I get hyper. My TPO antibodies are normal but my TPG are very elevated.I'd like to try ldn but am concerned it may throw me into hyper heaven. What test would indicated TSH receptor antibodies are affected? And is there a protocol for using ldn with Hashi's with sensitive responders?AB Re: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy

for 4 weeks -- Results

As far as ranges of TSH. You might refer your doctors to the current

American Association of clinical Endocrinologists TSH to be between .3-3.0

That was changed two years ago, but they have not informed everyone. The

average american without thyroid disease has a TSH of 1.5 , so we should

shoot for that.

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January 14, 2008

Hi AB,

I'm just another amateur here, so I'll share my experience and then hope

more knowledgeable folks will jump in.

On the Graves' boards we learn that each person has a set point in the

normal range of FT4 and FT3 where they feel best, and obviously you're found

yours. Mine is in the middle for both; some folks feel best near the top.

My experience was that I quickly stopped needing to take thyroid replacement

(a moderate amount, 60 mcg T4 and 10 mcg T3) and dropped it altogether.

Since then I've returned to a normal heart rate and feel euthyroid ( " just

right " ). The end result is that rather than making me hyper, LDN seems to

have healed my autoimmunity.

I'll get FT4 and FT3 in labs in 4-5 weeks, to make sure I'm getting accurate

results re my new status, and will get antibody labs in 3-4 months. (I have

no TPG, moderate TPO of 350, and moderate TSH receptor antibodies, TBII of

25).

bets wishes,

B.

________________________________

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of adelesbells

Sent: Monday, January 14, 2008 9:12 AM

low dose naltrexone

Subject: Re: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy

for 4 weeks -- Results

I'm new to this list and have Hashimoto's. I am medicated and my TSH is

usually very low but my FT3 and FT4 hover around the bottom end of the range

- and upping meds just makes me very symptomatic. Any small change in meds

or homones (especially estrogen hormone levels) really affects me and I get

hyper. My TPO antibodies are normal but my TPG are very elevated.

I'd like to try ldn but am concerned it may throw me into hyper heaven. What

test would indicated TSH receptor antibodies are affected? And is there a

protocol for using ldn with Hashi's with sensitive responders?

AB

January 14, 2008

I don't feel bad in the low end but not great either (fatigue) - any attempt to raise medication bottomed out my TSH (.01) and had very little affect on my ft3 or 4 - but I did feel hyper!How did you know when to stop meds? Do you stop the day you start ldn? I'm currently taking 75 mg Armour and 25 mg Synthroid.Sounds like I should get a TBII done as a baseline.Thanks - anyone know of docs trying this in Toronto?AB Re: [low dose naltrexone] Re: Sjogrens/hashimotos - taken LDN Therapy