FW: [Spotlight_ldn] Re: Leg Pains

[Guest guest]

I posted this in another LDN group for

info for everyone to read from Dr. Lawrence and then realized oops should

include the other group too. I hope this helps some out ;o)

From: I am Canadian

[mailto:lvlail_lvle@...]

Sent: Saturday, November 22, 2003

10:46 PM

Spotlight_ldn

Subject: [spotlight_ldn] Re: Leg

Pains

Hi Steve this is everything Dr. Lawrence

sent me so far ;o) Hope the info helps you. I am including the information he

sent regarding my own particular situation in case it’s anything like

someone elses and the information may be … well informative LOL

Re:

From: sparkins14

[mailto:sparkins@...]

Sent: Saturday, November 22, 2003

5:41 PM

Spotlight_ldn

Subject: [spotlight_ldn] Re: Leg

Pains

-

Thanks for the offer of the info. I'd like to have

a look.

These problems have become a real concern.

-- In Spotlight_ldn ,

" I am Canadian "

<lvlail_lvle@h...> wrote:

> Hi Steve,

>

>

>

> I understand from the literature Dr. Lawrence sent me that

while

on LDN it

> is still possible for the effects from past

attacks to occur as

those are

> from old lesions. Just likely that no new

attacks will happen. If

you want

> the info he sent me let me know and I will

forward them to you ;o)

>

>

>

> _____

>

> From: sparkins14 [mailto:sparkins@d...]

> Sent: Saturday, November 22, 2003 2:56 PM

> Spotlight_ldn

> Subject: [spotlight_ldn] Leg Pains

>

>

>

> I,ve now been on LDN for 3 months. In the

last while some problems

> with my feet, legs and hand have returned. I

get tingling, burning

> pain in my feet and now it has spread up my

legs. I also get this

> pain in my numb hand. Has anyone else

experienced this problem and

> do some intermittant symptoms continue even

on LDN. I feel like

all

> I do is take pain killers all day and night,

just to make this

> barely managable. I would much appreciate any

imput on this

subject.

>

>

Thanks

>

Steve

>

> You have to play the hand you are dealt, we

just got lousy dealers.

>

Dietary Research Limited

Gwynfa House, 10 Heol Gerrig, Treboeth, Swansea,

West Glam SA5 9BP

Tel: 01792 - 417514: Company Registered Number

2615367.

Ms Rainbolt, Canada.

Ref: n/a for the purposes

of this email

14th November 2003

Dear Ms Rainbolt,

Thank you for your interest in the use of low-dose

naltrexone (LDN) in the treatment of multiple sclerosis.

As explained in the accompanying information sheets,

this is a method that offers great benefits in stabilizing MS and preventing

further progression of the disease. In use, it also appears to be effective in improving

some specific symptoms, such as fatigue, muscle spasm, and muscle strength and

bladder function.

Despite the fact that naltrexone has been in use in the US, in the

treatment of MS, since 1985, and that the dose of the drug is extremely low

with minimal side-effects, it is important That you realize it must still be

considered as experimental, and that the absence of side-effects and the

occurrence of benefits cannot be guaranteed.

With access to the Internet you can contact Dr

Bihari’s website directly on www.low dose naltrexone.org.

This will provide full details of the use of LDN in MS and a number of other

conditions.

In addition, because LDN stimulates the immune system

and many of the drugs routinely used in the treatment of MS further

suppress the immune system, LDN cannot be used in company with, beta

interferon, methotrexate, azathioprine, mitozantrone, steroids, or any other

immune suppressant drug. If there is any doubt, please submit a full list of

the drugs you are presently taking so that their compatibility may be assessed

Also, because LDN will also block the analgesic effects

of any opiate drugs (includes codeine, dihydrocodeine, Tramadol, morphine,

pethidine or diamorphine) presently being taken the use of LDN will initially

greatly increase the level of pain experienced. It is therefore advisable that

any opiate-like drugs be discontinued at least two weeks before this treatment

is initiated.

LDN will have no adverse effects on any nutritional

therapy that you are taking. I personally take both LDN and a vast range of

nutritional supplements.

You may also find interest in some of the other

treatment methods available. Information sheets, describing these, are attached

Some of these methods, such as diet, zinc supplements,

or the anthocyanidins, I have found to be greatly beneficial. Others, such as

thalidomide or cannabis, both of which have been suggested as treatments for

MS, I am inclined to advise against.

Also attached is a complete list of other available

information sheets. Please let me know if you would also like copies of any of

these.

Please allow yourself plenty of time to read and

consider these various methods and, if you have any further questions or needs,

I shall be pleased to advise you.

Sadly, your neurologist has very little that can be

provided in the treatment of MS. Apart from a few drugs used to treat specific

symptoms, such as muscle spasm, the two main drugs used are steroids and beta

interferon. Steroids have a short-term benefit only, and are known to

hasten the progress of the MS when they wear off. Beta interferon is so

expensive and, in my opinion, a dangerous and risky drug, that it is rarely

used.

LDN appears to be far more reliable in preventing

further progress of the MS and the simplicity of treatment (just one capsule

each day) and the very low level of toxicity are additional advantages over the

conventional drugs. In my experience of this method, only about 2% of

patients on LDN decide to stop taking it due to lack of response and I have

found the method to be almost absolutely effective in controlling further

progress of the disease.

I regret that I am unfamiliar with the treatment method

that you describe (teriflunomide). I will seek out further infformation on this

method at the earliest opportunity.

You alsomention " chemo " (presumably,

chemotherapy). It would be of interest to know the precise nature of the

drug used for this purpose. I do not approve of this method of

treatment. It is simply inappropriate and illogical to treat a

disease which occurs because the immune system is already compromised.

Immune-suppressant chemotherapy drugs are also known double the risk of

developing cancer. The immune stimulent effect of LDN is far more

appropriate and, apparently far more effective!

Regarding your previous use of steroids, I would suggest

that you avoid such treatment in the future. Apart from the usual triad of side-effects

due to steroids, (hypertension, diabetes, and osteoporosis) these drugs also

are known to accelerate the rate of progression of the MS.

If you already have signs of osteoporosis you should be

taking high doses of both calcium (1000-1200 mg)and magnesium (400-500

mg) and, at least 2000 int. units (50 mcg) of vitamin D. I know that

Dr Ashton Embry recommends more in MS but I consider that just 50 mcg is

enough.

The Naproxen is ill-advised in MS. It will seriously

retard any possible recovery from the disease.

As you are in Canada

I am sure that you would find it very easy to simply obtain a prescription from

your own doctor for the LDN and obtain it directly, if not from a pharmacy

in your own area, then from one of the pharmacies in New York listed on the LDN website.

Please let me know of any further needs.

Yours sincerely,

Bob Lawrence

(Dr M R Lawrence)

-----Original Message-----

From: Rainbolt

[mailto:s.rainbolt@...]

Sent: 13 November 2003 22:08

I don’t think he wants everyone to have this…

Subject: MS patient in Canada

interested in LDN ~ friend of a patient of yours

Dear Dr. Lawrence,

We have not been properly introduced, yet

a patient of yours, , has urged me to contact you. I have had

Multiple Sclerosis for about eight years now, nearly nine. I am 28 nearly 29

years old and am currently on a drug study through Dr. O’Connor at

the MS Clinic at St. ’s Hospital here in Toronto, Ontario, Canada.

For the last three to four weeks I have

been studying what I can find on the net regarding Low Dose Naltrexone and it

all looks so good. I have always said if they cannot find a darned cure just

something to stop it where it is would be great and so far from what I have

read that is what LDN appears to do ( for a large number). Not to mention with

less side effects than the other nasties pushed on us by big pharma. The study

I am currently on is for teriflunomide a mixture of Arrava and chemo. I have

been on it for over two years now and have learned I have been on the real

thing the whole term at the higher dose of chemo being 7.5 grams (oops should have said mg’s)

I believe per pill. I had tried Avonex prior but found my MS seemed worse

and halted continuing with it due to the worsening of symptoms, new symptoms

& anxiety over self injection. It was all too much for me. I have done

prednisone and it no longer has effects on me of any positive nature, In fact I

went from a size 12 to an 18 on it. I am back to a 12-14 thank goodness but

weight is not the issue, I understand bone loss/decalcification is a worry with

too many steroids. After having my first IV of Solumedrol I experienced pelvic

bone pain and bone pain in the surrounding area. Dr. O’Connor did

no serious investigation of it. And the second time I had awful freezing pains

during the infusion. A bone scan has come back positive for some bone loss but

my GP is unable to tell yet whether it is from necrosis or arthritis… I

have a lot of arthritis in the family so the thought would not be surprising to

me, but the pain is ridiculous and chronic. Anyhow I am to see a rheumatologist

when one can find the time for me…

Getting to the point of the email, I

would very much like to come off this study medicine and try LDN. I have had an

attack in the last two weeks and as we don’t know if I have reacted to

Solumedrol I have been advised not to take it to try and stop the present

attack. I do not believe the study medication has helped me any; I have

continued to spiral downhill. Since beginning it I have gotten clonus in one

leg and have had massive numbness to a large percentage of my body as well as

weakened legs ~ my muscles are in good condition as before my last relapse I

was able to ride a bike during the summer to get muscle back. My main issues

right now are pins and needles large numbness feeling of cut off circulation in

several areas bone pain headaches optical neuritis and nausea especially when

bending head forward as well as fatigue (mostly physically) as well as short

temperedness probably due to the frustrations of all the pre-mentioned issues

& bladder problems including frequency and inability to fully release as

well as urgency. I am currently taking Birth Control (as I am not allowed to

get pregnant while on the study meds) and I am taking Apo-Naproxen 375 MG (was 2

daily now been upped to 3 daily by GP) for the bone pain and I take 1 B-12 (50

mcg) vitamin as well as vitamin 1 A & D (5,000 IU of A and 400 IU of D) and 1

Magnesium (50mg) daily. These are my only medications. I have no known drug

allergies (except perhaps Solumedrol). I do not know if you can help me with a

prescribing doctor here for LDN (I am pretty certain Dr. O’Connor

won’t as he is so involved with big pharma). I have joined a couple of

LDN groups and a forum. And had heard about you prior in our groups as being

positive about prescribing LDN for M.S. perhaps you can help me out.

If you cannot I understand and will try

to push forward with my situation.

Thank you for taking the time to read

this,

Rainbolt

[Guest guest]

Wow thank

you that’s allot of worthwhile information. J

son

Owner/

operator

Friends with MS.com

-----Original Message-----

From: I am Canadian

[mailto:lvlail_lvle@...]

Sent: Sunday, November 23, 2003

1:56 PM

To:

low dose naltrexone

Subject: [low dose naltrexone] FW:

[spotlight_ldn] Re: Leg Pains

I posted this in another

LDN group for info for everyone to read from Dr. Lawrence and then realized

oops should include the other group too. I hope this helps some out ;o)

From: I am

Canadian [mailto:lvlail_lvle@...]

Sent: Saturday, November 22, 2003

10:46 PM

Spotlight_ldn

Subject: [spotlight_ldn] Re: Leg

Pains

Hi Steve this is

everything Dr. Lawrence sent me so far ;o) Hope the info helps you. I am

including the information he sent regarding my own particular situation in case

it’s anything like someone elses and the information may be … well

informative LOL

Re:

From:

sparkins14 [mailto:sparkins@...]

Sent: Saturday, November 22, 2003

5:41 PM

Spotlight_ldn

Subject: [spotlight_ldn] Re: Leg

Pains

-

Thanks for the offer of the info. I'd like to have

a look.

These problems have become a real concern.

-- In Spotlight_ldn , " I am

Canadian "

<lvlail_lvle@h...> wrote:

> Hi Steve,

>

>

>

> I understand from the literature Dr. Lawrence

sent me that while

on LDN it

> is still possible for the effects from past

attacks to occur as

those are

> from old lesions. Just likely that no new

attacks will happen. If

you want

> the info he sent me let me know and I will

forward them to you ;o)

>

>

>

> _____

>

> From: sparkins14 [mailto:sparkins@d...]

> Sent: Saturday, November 22, 2003 2:56 PM

> Spotlight_ldn

> Subject: [spotlight_ldn] Leg Pains

>

>

>

> I,ve now been on LDN for 3 months. In the

last while some problems

> with my feet, legs and hand have returned. I

get tingling, burning

> pain in my feet and now it has spread up my

legs. I also get this

> pain in my numb hand. Has anyone else

experienced this problem and

> do some intermittant symptoms continue even

on LDN. I feel like

all

> I do is take pain killers all day and night,

just to make this

> barely managable. I would much appreciate any

imput on this

subject.

>

>

Thanks

>

Steve

>

> You have to play the hand you are dealt, we

just got lousy dealers.

>

Dietary

Research Limited

Gwynfa House, 10 Heol Gerrig, Treboeth,

Swansea, West Glam SA5 9BP

Tel: 01792 - 417514: Company

Registered Number 2615367.

Ms Rainbolt, Canada.

Ref: n/a

for the purposes of this email

14th November 2003

Dear Ms Rainbolt,

Thank you for your interest in the use of

low-dose naltrexone (LDN) in the treatment of multiple sclerosis.

As explained in the accompanying information

sheets, this is a method that offers great benefits in stabilizing MS and

preventing further progression of the disease. In use, it also appears to be

effective in improving some specific symptoms, such as fatigue, muscle spasm,

and muscle strength and bladder function.

Despite

the fact that naltrexone has been in use in the US, in the treatment of MS,

since 1985, and that the dose of the drug is extremely low with minimal

side-effects, it is important That you realize it must still be considered as

experimental, and that the absence of side-effects and the occurrence of

benefits cannot be guaranteed.

With access to the Internet you can contact

Dr Bihari’s website directly on www.low dose naltrexone.org.

This will provide full details of the use of LDN in MS and a number of other

conditions.

In addition, because LDN stimulates the

immune system and many of the drugs routinely used in the treatment of MS

further suppress the immune system, LDN cannot be used in company with, beta

interferon, methotrexate, azathioprine, mitozantrone, steroids, or any other

immune suppressant drug. If there is any doubt, please submit a full list of

the drugs you are presently taking so that their compatibility may be assessed

Also, because LDN will also block the

analgesic effects of any opiate drugs (includes codeine, dihydrocodeine,

Tramadol, morphine, pethidine or diamorphine) presently being taken the

use of LDN will initially greatly increase the level of pain experienced. It is

therefore advisable that any opiate-like drugs be discontinued at least two

weeks before this treatment is initiated.

LDN will have no adverse effects on any

nutritional therapy that you are taking. I personally take both LDN and a vast

range of nutritional supplements.

You may also find interest in some of the

other treatment methods available. Information sheets, describing these, are

attached

Some of these methods, such as diet, zinc

supplements, or the anthocyanidins, I have found to be greatly beneficial.

Others, such as thalidomide or cannabis, both of which have been suggested as

treatments for MS, I am inclined to advise against.

Also attached is a complete list of other

available information sheets. Please let me know if you would also like copies

of any of these.

Please allow yourself plenty of time to read

and consider these various methods and, if you have any further questions or

needs, I shall be pleased to advise you.

Sadly, your neurologist has very little that

can be provided in the treatment of MS. Apart from a few drugs used to treat

specific symptoms, such as muscle spasm, the two main drugs used are steroids

and beta interferon. Steroids have a short-term benefit only, and are

known to hasten the progress of the MS when they wear off. Beta

interferon is so expensive and, in my opinion, a dangerous and risky drug, that

it is rarely used.

LDN appears to be far more reliable in

preventing further progress of the MS and the simplicity of treatment (just one

capsule each day) and the very low level of toxicity are additional advantages

over the conventional drugs. In my experience of this method, only about

2% of patients on LDN decide to stop taking it due to lack of response and I

have found the method to be almost absolutely effective in controlling further

progress of the disease.

I regret that I am unfamiliar with the

treatment method that you describe (teriflunomide). I will seek out further

infformation on this method at the earliest opportunity.

You alsomention " chemo "

(presumably, chemotherapy). It would be of interest to know the precise

nature of the drug used for this purpose. I do not approve of this method

of treatment. It is simply inappropriate and illogical to treat

a disease which occurs because the immune system is already compromised.

Immune-suppressant chemotherapy drugs are also known double the risk of

developing cancer. The immune stimulent effect of LDN is far more

appropriate and, apparently far more effective!

Regarding your previous use of steroids, I

would suggest that you avoid such treatment in the future. Apart from the usual

triad of side-effects due to steroids, (hypertension, diabetes, and osteoporosis)

these drugs also are known to accelerate the rate of progression of the MS.

If you already have signs of osteoporosis

you should be taking high doses of both calcium (1000-1200 mg)and magnesium

(400-500 mg) and, at least 2000 int. units (50 mcg) of vitamin D. I

know that Dr Ashton Embry recommends more in MS but I consider that just

50 mcg is enough.

The Naproxen is ill-advised in MS. It will

seriously retard any possible recovery from the disease.

As you are in Canada I am sure that you

would find it very easy to simply obtain a prescription from your own

doctor for the LDN and obtain it directly, if not from a pharmacy in your

own area, then from one of the pharmacies in New York listed on the LDN

website.

Please let me know of any further needs.

Yours sincerely,

Bob Lawrence

(Dr M R Lawrence)

-----Original Message-----

From: Rainbolt

[mailto:s.rainbolt@...]

Sent: 13 November 2003 22:08

I don’t think he wants everyone to have this…

Subject: MS patient in Canada interested

in LDN ~ friend of a patient of yours

Dear Dr.

Lawrence,

We have not been

properly introduced, yet a patient of yours, , has urged me to

contact you. I have had Multiple Sclerosis for about eight years now, nearly

nine. I am 28 nearly 29 years old and am currently on a drug study through Dr.

O’Connor at the MS Clinic at St. ’s Hospital here in

Toronto, Ontario, Canada.

For the last

three to four weeks I have been studying what I can find on the net regarding

Low Dose Naltrexone and it all looks so good. I have always said if they cannot

find a darned cure just something to stop it where it is would be great and so

far from what I have read that is what LDN appears to do ( for a large number).

Not to mention with less side effects than the other nasties pushed on us by

big pharma. The study I am currently on is for teriflunomide a mixture of

Arrava and chemo. I have been on it for over two years now and have learned I

have been on the real thing the whole term at the higher dose of chemo being

7.5 grams (oops should have said

mg’s) I believe per pill. I had tried Avonex prior

but found my MS seemed worse and halted continuing with it due to the

worsening of symptoms, new symptoms & anxiety over self injection. It was

all too much for me. I have done prednisone and it no longer has effects on me

of any positive nature, In fact I went from a size 12 to an 18 on it. I am back

to a 12-14 thank goodness but weight is not the issue, I understand bone

loss/decalcification is a worry with too many steroids. After having my first

IV of Solumedrol I experienced pelvic bone pain and bone pain in the

surrounding area. Dr. O’Connor did no serious investigation of it. And

the second time I had awful freezing pains during the infusion. A bone scan has

come back positive for some bone loss but my GP is unable to tell yet whether

it is from necrosis or arthritis… I have a lot of arthritis in the family

so the thought would not be surprising to me, but the pain is ridiculous and

chronic. Anyhow I am to see a rheumatologist when one can find the time for

me…

Getting to the

point of the email, I would very much like to come off this study medicine and

try LDN. I have had an attack in the last two weeks and as we don’t know

if I have reacted to Solumedrol I have been advised not to take it to try and

stop the present attack. I do not believe the study medication has helped me

any; I have continued to spiral downhill. Since beginning it I have gotten

clonus in one leg and have had massive numbness to a large percentage of my

body as well as weakened legs ~ my muscles are in good condition as before my

last relapse I was able to ride a bike during the summer to get muscle back. My

main issues right now are pins and needles large numbness feeling of cut off

circulation in several areas bone pain headaches optical neuritis and nausea

especially when bending head forward as well as fatigue (mostly physically) as

well as short temperedness probably due to the frustrations of all the

pre-mentioned issues & bladder problems including frequency and inability

to fully release as well as urgency. I am currently taking Birth Control (as I

am not allowed to get pregnant while on the study meds) and I am taking

Apo-Naproxen 375 MG (was 2 daily now been upped to 3 daily by GP) for the bone

pain and I take 1 B-12 (50 mcg) vitamin as well as vitamin 1 A & D (5,000 IU

of A and 400 IU of D) and 1 Magnesium (50mg) daily. These are my only medications.

I have no known drug allergies (except perhaps Solumedrol). I do not know if

you can help me with a prescribing doctor here for LDN (I am pretty certain Dr.

O’Connor won’t as he is so involved with big pharma). I have

joined a couple of LDN groups and a forum. And had heard about you prior in our

groups as being positive about prescribing LDN for M.S. perhaps you can help me

out.

If you cannot I

understand and will try to push forward with my situation.

Thank you for

taking the time to read this,

Rainbolt

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