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Hi Becky

I am currently waiting for the results from my son's testing to see if

antiviral meds are what we need to do for him. You experince has frightened

me as well. can you please explain exactly hwat happened with your child? My

son is a very big kid and if it was a behavior (ie out of control behavior

reaction) that will be a definte concern for us.

Thanks for any info

JAN

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One more question. What improvements have has anyone seen in their child?

My son has moderate autism with bipolar and tourettes. We are absolutely

convinced that his autism was caused by a reaction to a virus or vaccine. We

know his tourettes was caused by strep. Any time his tourettes flairs up we

see a fairly serious regression with severe outbursts, OCD and other problems

too.

I am very curious to know of improvements.

Thanks

JAN

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We just started our 4 year old daughter on Kutapressin last week. She has

been on a few different anti-virals over the last year. She has made

improvement, but not what I would call vast improvement. We have not had any

bad reactions to the medications so far. And the Kutapressin injections are

going fine - we give them to her after she goes to sleep. We have not seen

any changes yet - but Dr. Goldberg said it will take anywhere from 2-6 weeks

to see any difference, if there is one. What kind of reactions did you see

in your son?

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Becky,

What happened when you tried the anti-virals. Goldberg

said there would be no reaction UNLESS Nick actually

had a viral problem but we saw almost total brainwipe from

Famvir (thank goodness we stopped it quickly). He is also

tlking Kutapressin with us.

scared

>From: Valleyhts@...

>

>I support the idea behind anti-viral meds for our kids, however my son's

>reaction to two anti-virals was HORRIBLE!!!!!!!! Now Dr. Goldberg is

>encouraging a trial run of Kutapressin so I need to hear from people who

have

>had 1) tried at least one oral anti-viral med with negative or no

>improvement results and 2) tried kutapressin. What were the results of the

>trial with Kutapressin?

>I am very, very scared because his experience was unbearable to him and to

my

>whole family. Please, please, please advise. Becky

>

>---------------------------

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,

What do you mean by " a total brainwipe " ? My son is on acyclovir (Zovirax)

and we have had some improvements. I think Dr. Goldberg plans to eventually

move him to another anti-viral such as Famvir, so I want to understand the

risks. Thanks.

Connie

scared

>

>

>>From: Valleyhts@...

>>

>>I support the idea behind anti-viral meds for our kids, however my son's

>>reaction to two anti-virals was HORRIBLE!!!!!!!! Now Dr. Goldberg is

>>encouraging a trial run of Kutapressin so I need to hear from people who

>have

>>had 1) tried at least one oral anti-viral med with negative or no

>>improvement results and 2) tried kutapressin. What were the results of

the

>>trial with Kutapressin?

>>I am very, very scared because his experience was unbearable to him and to

>my

>>whole family. Please, please, please advise. Becky

>>

>>---------------------------

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OK folks....I began this inquiry and had many people ask what WAS the

reaction? Well, our son is normally a very happy child with good self esteem

and self image. He is generally cooperative and laughs (appropriately)

numerous times per day. Suddenly, on valtrex and zivorax (tried separately

several months apart for at least a 5 -6 week duration each), he was

depressed and very non-compliant. His tantrums alienated him from his peers

at school. At home I thought he and I would both lose our minds. He would cry

at a drop of a hat and complained of headache. His tantrums, folks, were wild

and frightening. I remember one time calling the answering machine of Dr.

Goldberg's office begging to discontinue. Dr. Goldberg stated that this was

" die off " and to expect improvement " soon " but it went on....and on.... and

on and on for, like I said, up to six weeks. I finally called the office and

said that was enough. Without support, I stopped and within two days I saw my

little boy become happier until his true happiness returned soon afterward. I

swore that I would rather have a happy and content autistic kid than a

miserable, unhappy, screaming, punching, kicking, destructive non-autistic

kid any day........and now I am facing the kutapressin dilemma....

One time I remember hearing a lecture featuring Temple Grandin. She supports

medication use in children with autism, but warned, " if you do not see a

positive response in a timely manner, stop the medication! " I am really

struggling with this kutapressin because believe me, I remember the sadness,

depression, and you'd-think-we-were-killing-him style tantrums. (Let me

reiterate: I still believe this treatment regimen can help some children; I

am just not certain it can help mine.) Becky

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What type of testing is done to determine if antivirals or needed or not??

Thanks

scared

From: Valleyhts@...

I support the idea behind anti-viral meds for our kids, however my son's

reaction to two anti-virals was HORRIBLE!!!!!!!! Now Dr. Goldberg is

encouraging a trial run of Kutapressin so I need to hear from people who

have

had 1) tried at least one oral anti-viral med with negative or no

improvement results and 2) tried kutapressin. What were the results of the

trial with Kutapressin?

I am very, very scared because his experience was unbearable to him and to

my

whole family. Please, please, please advise. Becky

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My child has just begun Valtrex and is still in the viral die off period.

Between the absolutely crazy periods we are seeing wonderful glimpses of the

child we had not seen in years! Despite the die off her school work has

improved! Right now as I type she is leaping around the family room, talking

to herself, and barking BUT she had a great morning so we'll get through

this. Too bad we are having a heavy snowstorm and we are all locked in the

house though! Kathy

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You sound disappointed and frustrated. How long have you been working with

Dr. G and how old was your child when you started? I'm getting the impression

that many kids fit into the different sub categories of and are

relatively easy to treat but some do not and take more time. When we have

some more drugs to use (after the successful drug trials!) this may not be as

much of a problem! I'm aware of a lot of success stories. I hope that you too

will have one in a few years! Kathy

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My daughter is in the viral die off and very emotional. I figure that it took

years for her to get this way and it is going to take awhile for the damage

to be undone. What scares me is the progressive nature of this; immune

reactions turning into autoimmune. My child already has auto immunoglobins

against her thyroid. I can put up with her being crazy for months if that

means long term health. She so desperately wants to be like the other kids

that we are sticking with this despite the down side. Oh my daughter's

fasting blood sugar is 101 also. I watched a friends autistic son become a

diabetic. No thanks. Maybe the new drugs will help you son. Let's all hope

that we parents can raise the money needed and get these drug trials going!

That just may be the thing that will help your son! Kathy

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My daughters behavior started to deteriorate after the first 24 hours of the

half dose. One would think that you would have seen a reaction sooner but

these darn kids don't read the textbooks and do things their own way. What

does Dr. G think is going on? Kathy

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Diane - I found the best way to put the meds in my daughter was to grind them

up and layer the powder between layers of frozen, nondairy coolwhip on a

spoon. The first week she refused to take it and there was a lot of

screaming, biting, and gagging. Now she knows we won't stop with the meds, so

she opens her mouth and eats it!

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My son has been on Valtrex for approx. 3 weeks and I am now starting to see

a regression. I faxed the office and was told that it is not from the

Valtrex. I'm confused because I thought if it was going to work we would

see this negative effect. Does anyone have any thoughts on this?

Diane

Re: scared

>From: Valleyhts@...

>

>OK folks....I began this inquiry and had many people ask what WAS the

>reaction? Well, our son is normally a very happy child with good self

esteem

>and self image. He is generally cooperative and laughs (appropriately)

>numerous times per day. Suddenly, on valtrex and zivorax (tried separately

>several months apart for at least a 5 -6 week duration each), he was

>depressed and very non-compliant. His tantrums alienated him from his peers

>at school. At home I thought he and I would both lose our minds. He would

cry

>at a drop of a hat and complained of headache. His tantrums, folks, were

wild

>and frightening. I remember one time calling the answering machine of Dr.

>Goldberg's office begging to discontinue. Dr. Goldberg stated that this was

> " die off " and to expect improvement " soon " but it went on....and on....

and

>on and on for, like I said, up to six weeks. I finally called the office

and

>said that was enough. Without support, I stopped and within two days I saw

my

>little boy become happier until his true happiness returned soon afterward.

I

>swore that I would rather have a happy and content autistic kid than a

>miserable, unhappy, screaming, punching, kicking, destructive non-autistic

>kid any day........and now I am facing the kutapressin dilemma....

>One time I remember hearing a lecture featuring Temple Grandin. She

supports

>medication use in children with autism, but warned, " if you do not see a

>positive response in a timely manner, stop the medication! " I am really

>struggling with this kutapressin because believe me, I remember the

sadness,

>depression, and you'd-think-we-were-killing-him style tantrums. (Let me

>reiterate: I still believe this treatment regimen can help some children; I

>am just not certain it can help mine.) Becky

>

>---------------------------

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When is it typical to see a die off? Is it normal to see after 3 weeks of

the Valtrex? I'm also just curious, How do you get the Valtrex in her? I

put it in Tyler's milk but I have to cover it up with chocolate syrup. It

is the only way he takes it. Maybe I'm seeing a change from the chocolate

syrup.

Diane

Re: scared

>From: JOSKAT95@...

>

>My child has just begun Valtrex and is still in the viral die off period.

>Between the absolutely crazy periods we are seeing wonderful glimpses of

the

>child we had not seen in years! Despite the die off her school work has

>improved! Right now as I type she is leaping around the family room,

talking

>to herself, and barking BUT she had a great morning so we'll get through

>this. Too bad we are having a heavy snowstorm and we are all locked in the

>house though! Kathy

>

>---------------------------

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It is my understanding that die off occurs in the first 7-10 days; I have a

friend whose autistic daughter goes ballistic with corn syrup, which is

probably the main ingredient in your chocolate syrup. When my kids couldn't

swallow pills, I would crush them, dilute them in water, and squirt it in the

back of their mouth with a large syringe . (whatever works, right?)

Kate

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- What do you mean by " brainwipe " ? Spacey? Stimming?

Unresponsive? We have just started Famvir and I'm apprehensive and

want to be watching for anything of concern! --Kathleen--

>From: " mnms " <mnms@...>

>

>Becky,

>

> What happened when you tried the anti-virals. Goldberg

>said there would be no reaction UNLESS Nick actually

>had a viral problem but we saw almost total brainwipe from

>Famvir (thank goodness we stopped it quickly). He is also

>tlking Kutapressin with us.

>

>

>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>

Kathleen J. McClatchey (Whiteman) kjm@...

Executive Communications office phone: (734) 763-8190

Office of the Chief Information Officer fax: (734) 764-3988

5085 Fleming Administration Building cell phone: (734) 358-5122

University of Michigan home phone: (734) 944-1828

Ann Arbor, MI 48109

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We've tried 3 anti-virals with no improvements. The side effects have

been increased stimminess and sleep problems, but they haven't been

unbearable. We were on each anti-viral for at least a month. We started

Kutapressin several months ago. My son had flu-like symptoms off and on

for the first month. He's also had mouth sores with the Kutapressin (he

never had them before in his life). We are now on Kutapressin and

Valtrex. The mouth sores are better, but we still have not seen anything

positive. I think we are ready to throw in the towel with anti-virals.

We also have not had any success with anti-fungals.

Loretta

On Thu, 17 Feb 2000 12:53:25 EST Valleyhts@... writes:

> From: Valleyhts@...

>

> I support the idea behind anti-viral meds for our kids, however my

> son's

> reaction to two anti-virals was HORRIBLE!!!!!!!! Now Dr. Goldberg is

> encouraging a trial run of Kutapressin so I need to hear from people

> who have

> had 1) tried at least one oral anti-viral med with negative or no

> improvement results and 2) tried kutapressin. What were the results

> of the

> trial with Kutapressin?

> I am very, very scared because his experience was unbearable to him

> and to my

> whole family. Please, please, please advise. Becky

>

> ---------------------------

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Diane,

I have found that compounding Valtrex into a liquid by a pharmacist is

very convenient; and I don't have any trouble giving it to my child.

The pharmacist will use Stevia for a sweetner and a couple of drops for

flavoring; such as, banana, grape, or apple. Stevia is not real sugar

so it's okay for our children. I can actually drizzle the Valtrex on my

son's gluten free waffles and he'll eat it. I put it sometimes in

juice, but that is probably not the best way since juice has alot of

sugar. I have a friend that uses the banana flavor; and her daughter

will take it right from the dropper.

If you have any more questions or want the name of my pharmacy, please

call me at (949) 650-2464 or email me at DVMCarney@....

Vicki

Best Way Trucking Service wrote:

>

> From: " Best Way Trucking Service " <bestway@...>

>

> When is it typical to see a die off? Is it normal to see after 3 weeks of

> the Valtrex? I'm also just curious, How do you get the Valtrex in her? I

> put it in Tyler's milk but I have to cover it up with chocolate syrup. It

> is the only way he takes it. Maybe I'm seeing a change from the chocolate

> syrup.

>

> Diane

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just swallows the pills. She started taking pills long before she was

two because of her asthma. When she was little I put her pills in applesauce

or almost anything that would work! Kathy

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What does his lab work look like and how old is he? We are hoping to set up a

clinic and I am trying to get prepared! I suspect that some children

will be much harder to treat than others. I also suspect that the length of

treatment will vary greatly. I have some suspicions on why at this point.

What is your opinion? What should I be saying to parents to prepare them for

what might, initially be a long frustrating road? Would it help you if you

could talk to parents who have had an equally difficult time? What would help

you right now? Kathy

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I suspect that the die off period is variable and I am saying that because

while the majority may experience it within 7-10 days (and that makes

absolute sense) there are always going to be those that have a different

reaction. That is the benefit of going to a practitioner who has been in the

business for many years, they will have seen another idiosyncratic reaction!

Kathy

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You have made some great suggestions! I reduce the amount of sugar I use in

many things by using stevia. That is better for my daughter but also my

husband's waistline! If anyone is going to try it believe the label! A little

really does go a long way! Kathy

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