Re: Re: LDN explanation, insomnia

[Guest guest]

Makes sense. It is very similar for me as well.Delicious ideas to please the pickiest eaters. Watch the video on AOL Living.

[Guest guest]

I always take my dose about 11.30 pm, go to bed about midnight and half to one hour later I sleep more deeply than I used to before starting LDN. Sometimes I wake up for a few seconds one or more times between 3.30 - 5 am because I am very thirsty and I sleep again after I have a glass of water. Can anybody explain that? It never happened before LDN and I wonder what it means. By nature I need minimal amounts of water and try to drink more than I need during the day.

Best wishes

Katerina

[low dose naltrexone] Re: LDN explanation, insomnia

Last night I took my dose at 11:30 and went to sleep at midnight. My sleep was more deep then when I have taken it at 9:30 and went to sleep at midnight.>> Ok here goes: > Currently I've modified my strategy to take the LDN at the first twinges of sleepiness and with a small bit af food in the stomach to further delay absorption slightly. I suspect that insomnia may be due to the following mechanism, which is not as yet been demonstrated in any research that I'm aware of. I think initial increased nighttime production of endorphins/enceephlins may provide the initial opioid surge to nudge us off to sleep, and if one prevents that surge by taking the Naltrexone too early this won't occur. I don't know of what changes in receptors may occur over time that change this initial tendancy. Again, this is conjecture but makes a fair amount of biomechanical sense, and may explain why, if one is endorphin depleted due to chronic disease, that they tend towards insomnia sending one into a viscious cycle of persistant endorphin depletion.> > Let me know if any of what I posit is factual> > red pill> > > ---------------------------------> Be a better friend, newshound, and know-it-all with Mobile. Try it now.>

[Guest guest]

Trying to understand this theory. Red pill are you saying if you take LDN and

stay up it is not going to work. You have to go to sleep to make it work? I

guess I'm in trouble...

Crol

-------------- Original message ----------------------

From: red pill <thatredpill@...>

> Ok here goes:

> Currently I've modified my strategy to take the LDN at the first twinges of

> sleepiness and with a small bit af food in the stomach to further delay

> absorption slightly. I suspect that insomnia may be due to the following

> mechanism, which is not as yet been demonstrated in any research that I'm

aware

> of. I think initial increased nighttime production of endorphins/enceephlins

> may provide the initial opioid surge to nudge us off to sleep, and if one

> prevents that surge by taking the Naltrexone too early this won't occur. I

> don't know of what changes in receptors may occur over time that change this

> initial tendancy. Again, this is conjecture but makes a fair amount of

> biomechanical sense, and may explain why, if one is endorphin depleted due to

> chronic disease, that they tend towards insomnia sending one into a viscious

> cycle of persistant endorphin depletion.

>

> Let me know if any of what I posit is factual

>

> red pill

>

>

> ---------------------------------

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

Ok here goes: Currently I've modified my strategy to take the LDN at the first twinges of sleepiness and with a small bit af food in the stomach to further delay absorption slightly. I suspect that insomnia may be due to the following mechanism, which is not as yet been demonstrated in any research that I'm aware of. I think initial increased nighttime production of endorphins/enceephlins may provide the initial opioid surge to nudge us off to sleep, and if one prevents that surge by taking the Naltrexone too early this won't occur. I don't know of what changes in receptors may occur over time that change this initial tendancy. Again, this is conjecture but makes a fair amount of biomechanical sense, and may explain why, if one is endorphin depleted due to chronic disease, that they tend towards insomnia sending one into a viscious cycle of persistant endorphin depletion. Let me know if any

of what I posit is factual red pill

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

[Guest guest]

You take LDN after 9pm Standard Time, Before 3am

That's it, that's the protocol.

I worked mainly 12-8am for years, when I started LDN I took it between 1230 and 130, sometimes as late as 230. I slept from 7pm til 11:30pm.

http://ldninfo.org/further_q_and_a.htm 4th question

Re: [low dose naltrexone] Re: LDN explanation, insomnia

Trying to understand this theory. Red pill are you saying if you take LDN and stay up it is not going to work. You have to go to sleep to make it work? I guess I'm in trouble...Crol

[Guest guest]

Ok here goes: Currently I've modified my strategy to take the LDN at the first twinges of sleepiness and with a small bit af food in the stomach to further delay absorption slightly. I suspect that insomnia may be due to the following mechanism, which is not as yet been demonstrated in any research that I'm aware of. I think initial increased nighttime production of endorphins/enceephlins may provide the initial opioid surge to nudge us off to sleep, and if one prevents that surge by taking the Naltrexone too early this won't occur. I don't know of what changes in receptors may occur over time that change this initial tendancy. Again, this is conjecture but makes a fair amount of biomechanical sense, and may explain why, if one is endorphin depleted due to chronic disease, that they tend towards insomnia sending one into a viscious cycle of persistant endorphin depletion. Let me know if any of what I posit is factual

I have no idea if what you say is factual, but I must take the LDN at nine PM and then I sleep like a baby after ten pm.... go figure?

Celia

I have no idea

[Guest guest]

I think all of us have to find their own rythm due to taking LDN. As far as it is betw. 09.00 and 02.00.

My problem has never been insomnia, as far as insomnia means trouble in getting to sleep (at night) when we want (?),

my problem has always been waking up several times in the middle of the night, full of energy, and then having trouble to sleep for a while.....(30 minutes or more bf sleeping again)....

I found out that I couldn't take LDN just before I go to bed, lets say 11.30 pm - 12.00 pm,

but I have to take it 10.00. Never later than that. Have got enough and good sleep at night three weeks now. :-)

Ingrid

Re: [low dose naltrexone] Re: LDN explanation, insomniaTrying to understand this theory. Red pill are you saying if you take LDN and stay up it is not going to work. You have to go to sleep to make it work? I guess I'm in trouble...Crol-------------- Original message ----------------------From: red pill <thatredpill@...>> Ok here goes: > Currently I've modified my strategy to take the LDN at the first twinges of > sleepiness and with a small bit af food in the stomach to further delay > absorption

slightly. I suspect that insomnia may be due to the following > mechanism, which is not as yet been demonstrated in any research that I'm aware > of. I think initial increased nighttime production of endorphins/enceephlins > may provide the initial opioid surge to nudge us off to sleep, and if one > prevents that surge by taking the Naltrexone too early this won't occur. I > don't know of what changes in receptors may occur over time that change this > initial tendancy. Again, this is conjecture but makes a fair amount of > biomechanical sense, and may explain why, if one is endorphin depleted due to > chronic disease, that they tend towards insomnia sending one into a viscious > cycle of persistant endorphin depletion.> > Let me know if any of what I posit is factual> > red pill> >

> ---------------------------------Be a better friend, newshound, and know-it-all with Mobile. Try it now.

[Guest guest]

HI INGRID - that's what i plan on doing, too!! using the cream earlier in the night, instead of midnight!! hopefully, it will help me with sleep problems, too!! although, i never sleep straight thru the night anyway!!

marshirisDelicious ideas to please the pickiest eaters. Watch the video on AOL Living.