Re: Been doing some investigating on 2am-4am arousal/maybe endorphin connected

[Guest guest]

-,

I agree with you totally. However, I suspect some may have opposite

body rhythms. Now, whether this is natural or not, who knows??!!

I bet the vast majority do best on the night time dosing, but some may

have different body rhythms, like I said.

I would guess giving LDN a try during the day, if that is the only

time that is possible for you, would be better than not trying it at

all. Maybe a body rhythm can be changed.? Maybe a severe lack of

endorphins can begin to be corrected with day time dosing. After

sufficient time has passed to allow the body to get used to these

endorphins, a night time schedule could be implemented,,,maybe then it

would be easier and more successful.

I guess I am thinking out loud too...LOL..but I would say give it a

try, you have nothing to loose, and after things are going really

well, and you know you can feel a difference and feel you are stable,

try to switch to night time. I am sure you will find out real quick

whether it will work for you or not.

Saundra

-- In low dose naltrexone , " Bren " <b63powell@...> wrote:

>

>

> Been doing some investigating on 2am-4am arousal/maybe endorphin

> connected.

>

> If Dr. Bihari is correct that our largest endorphin prodution is from

> 2am to 4am it also may explain why many people awaken during this time

> frame in the night. I have been reading so much on parents who have

> children waking during this time frame, night terrors occuring during

> this time. Is peak endorphin production the cause of this. I am

> really beginning to believe that yes, our peak endorphin production

> hours are from 2am to 4am. I wish we had a doctor reading here to

> investigate this by laboratory tests on human beings.

>

> Anyone else thought about this?

>

> Just my brain in overdrive these days.

>

>

>

[Guest guest]

Dr. McCandless is unable to do this?

>

>

> Been doing some investigating on 2am-4am arousal/maybe endorphin

> connected.

>

> If Dr. Bihari is correct that our largest endorphin prodution is

from

> 2am to 4am it also may explain why many people awaken during this

time

> frame in the night. I have been reading so much on parents who

have

> children waking during this time frame, night terrors occuring

during

> this time. Is peak endorphin production the cause of this. I am

> really beginning to believe that yes, our peak endorphin production

> hours are from 2am to 4am. I wish we had a doctor reading here to

> investigate this by laboratory tests on human beings.

>

> Anyone else thought about this?

>

> Just my brain in overdrive these days.

>

>

>

[Guest guest]

The pituitary's role in TSH production is peak around the 2am time

frame so I suspect that all the other processes...FSH, MSH, and the

endorphins are also peaking around this time too.

Jann

[Guest guest]

> >

> > -,

> > I agree with you totally. However, I suspect some may have opposite

> > body rhythms. Now, whether this is natural or not, who knows??!!

> > I bet the vast majority do best on the night time dosing, but some

> may

> > have different body rhythms, like I said.

> > I would guess giving LDN a try during the day, if that is the only

> > time that is possible for you, would be better than not trying it

at

> > all. Maybe a body rhythm can be changed.? Maybe a severe lack of

> > endorphins can begin to be corrected with day time dosing. After

> > sufficient time has passed to allow the body to get used to these

> > endorphins, a night time schedule could be implemented,,,maybe

then

> it

> > would be easier and more successful.

> > I guess I am thinking out loud too...LOL..but I would say give it a

> > try, you have nothing to loose, and after things are going really

> > well, and you know you can feel a difference and feel you are

stable,

> > try to switch to night time. I am sure you will find out real quick

> > whether it will work for you or not.

> > Saundra

> ==========

Goodness, I should have re-read that. Let's fix first paragraph.

> Not sure if more than 3 of us with progressive MS tried to switch

from nightime LDN to daytime LDN and failed that test, 3 of us were

seeing our disease awaken again AFTER we switched from nightime LDN to

daytime LDN, one was a former patient of Dr. Bihari's. I was doing

great on nightime LDN but had a female issue caused by LDN. I was one

of those that swiched to daytime from nightime after being on

LDN at night a few years and within 5 days of taking LDN in daytime I

was headed back to almost needing my mobility scooter. I was having

female trouble caused by LDN and I thought a trial of daytime LDN use

might remedy my problem. My MS started to get worse again so I

switched back to nightime and found something else to remedy my female

problem.

Anyone else with chronic progressive, NOT relapsing/remitting but

chronic progressive Multiple Sclerosis who got a halt in disease

progression on nightime LDN dosing try changing from night time to

daytime LDN dosing? If so, what were your results? Better, bad, no

change?

>

The reason I'm more interested in chronic progressive MS'ers is Dr. M.

Gironi has found Beta Endorphins to be lower in chronic progressive MS

sufferers than those with relapsing/remitting MS.

>

>

>

[Guest guest]

>

> The pituitary's role in TSH production is peak around the 2am time.

Thanks, Jann, I was unaware of that. I now need to go dig around in

that area. But on another day, I'm exhausted from my day today.

[Guest guest]

Since I started LDN (11.30 pm) I wake up some time between 3-4 am almost every night, have a glass of water and fall asleep immediately after. This was not like me before and I think it has to do with endorphin levels.

Katerina

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