Member's post

[Guest guest]

There is a member on the LDN4cancer site who has issue with the LDN

dosing " Time " at night... She doesn't think the " night time " dosing

is not the only time but anytime during the day.

Below is her current email to the group. Maybe someone here can

contribute? I quoted 's previous posts to no avail.

" First, as I have privately, I would like to thank

you for starting this forum. I think it was and

is a very courageous thing to do and I admire

the spirit in which it was begun. You have made

available to all of us, a very good opportunity

to participate in this discussion and learn a great

deal about fighting cancer. And as for posting your

medical records, I applaud you for that and would

encourage you, if you haven't already done so,

to describe in detail your LDN protocol along

with all supplemental therapies you are using.

I would also urge you and everyone else here

find a way where we can collect our individual

medical records and LDN protocols in order to

justify a possible request to the NIH for clinical

trials. I would like to discuss with you privately

the possibility of posting my own records along

with yours for the purposes stated above and

for purposes of setting an example and of putting

my money where my mouth is, so to speak.

One of the reasons you are still alive is that Ian

Zagon discovered a mechanism triggered by naltrexone.

He didn't tell Bihari about it, Bihari read it in the

paper

Dr. Zagon wrote to report the discovery and contacted

Ian Zagon. True, Bihari took LDN himself but such a

solipsistic approach does not adequately replace

clinical

trials. Bihari seized on Dr. Zagon's research,

applying

the rat model directly to humans without further

research.

This was reckless and he was fortunate no paying

patient

suffered and died as a result. Still the AIDs study

reveals

that some lost their lives under his care. But these

were

AIDs patients and their deaths were not alarming. And

'extensive use' of LDN is hardly what you would call

its

use by three to five hundred people.

What you call " randomized....as the medical industry

like(s) to propagate " is known as scientific method.

This is very desirable. The alternative is a sort of

modern

'witch doctoring'. There is a large element of this

in our

using LDN without knowing for a scientific certainty

that

LDN will have positive effects within our individual

body

chemistries and on our particular cancers. We are all

willing to take whatever are the associated risks in

exchange for the potential benefits, but that does not

in

any way reduce the desirability of clinical trials.

The completion of such trials would make LDN therapy

immediately available to people who, like Tiaq, need

scientific evidence of LDN's efficacy.

But something like religious fervor has got be at the

source of this dosing dogma. How can you insist that

someone take LDN at night if they're having serious

sleep

disturbances or having severe pain which demands the

use of opiates? Research has come a long way since

Bihari

began treating people with LDN. It is very good that

many

people are helped by LDN, but at the same time

thousands

and thousands more are not being helped because

Bihari's

willy-nilly approach has given such a bad name to LDN

in

the minds of those professionals in the medical

community

who could otherwise prescribe LDN in so many settings.

And as I said, scientific knowledge is not static or

absolute

and so it would behoove everyone in the LDN community

to make themselves aware of why and how the drug

they're using is helping them or not, and not just

rely on

the repetitious drone of Bihari dogma.

I'm not suggesting that you change your dosing

schedule,

but I do think it is problematic that you insist

others follow

that ritual. And Dee, you have at least twice that I'm

aware

of, given that advice to people who were having

serious

problems with night time dosing. I think such advice

is

beyond the scope of this forum, and without knowledge

of a person's complete medical history, none of us is

equipped

to prescribe any protocol.

I agree both Bihari and Zagon have made contributions,

but I remind you again that Dr. Zagon discovered the

LDN

effect using rat models. And he and his team are

continuing

research in human subjects in the context of the Penn

State

School of Medicine where Dr. Zagon is a distinguished

professor

of medicine at the graduate level. And Bihari took

that research

twenty years ago and prematurely and applied it to

humans.

You took that leap of faith which you disparage,

apparently

unknowingly. So I urge you and everyone interested in

LDN

to take a look at this link which gives a brief

overview of what

Dr. Zagon and his team are doing.

http://www.hmc.psu.edu/neuroscienceresearch/admin/facultybiopages/zagon.htm

You will see that Dr. Zagon's research is applied to

human

needs. And on the point you make that his work is

limited to lab animals, I must vigorously disagree.

His

work proceeds in the way that scientific method

requires,

and again I suggest strongly that we as patients using

LDN familiarize ourselves with how and why it works as

it does. I also strongly urge anyone who is

interested in

making this treatment, this very compassionate

treatment,

available to more and more people, to contribute to

and

support the work, the research and the clinical trials

being

conducted by Ian Zagon and his colleagues. The work

is time consuming and costly, exacting and intricate.

We all owe a debt of gratitude to this man of

honorable

motivation and his inspired team. So please, no more

derision of him and his work. Let's give each his due

and not get caught up in egos and personalities, but

where there has been error let's acknowledge it and

move on with open and transparent discussion. "

Respectfully, Jackie

[Guest guest]

I have no wish to be drawn in to

the Zagon V Bihari debate. As far as I am concerned anyone and everyone who has

contributed to the progress of LDN deserves due credit.

However I believe that there is a blatant

inaccuracy in the statement which I have quoted below, which needs to be

corrected.

My understanding is that Dr Bihari was treating

drug addicts with naltrexone in accordance with the FDA approved protocol. Many

of these addicts went on to develop aids. Obviously drug addicts are in a high risk

group for contracting aids. However Dr Bihari realised that the FDA

approved dose of naltrexone was blocking the immune system, & he started to

experiment with lower doses, & this led to LDN as we now know it.

Read more at:

Dr. Kamau B. Kokayi Interviews Dr. Bihari September 23, 2003

WBAI in New York City

" Global Medicine Review”

http://www.gazorpa.com/interview.html

Tommy

Member's post

Posted by:

" deealejo " deealejo@...

deealejo

Sat May 10, 2008

4:34 pm (PDT)

There is a member on the LDN4cancer site who has issue with the LDN dosing

" Time " at night... She doesn't think the " night time "

dosing is not the only time but anytime during the day.

Below is her current email to the group. Maybe someone here can contribute?

“……………………..…..Bihari

seized on Dr. Zagon's research, applying the rat model directly to humans

without further

research. This was reckless and he was fortunate no paying patient suffered and

died as a result. Still the AIDs study

reveals that some lost their lives under his care. But these were AIDs patients

and their deaths were not alarming. And

'extensive use' of LDN is hardly what you would call its use by three to five

hundred people…………………………....

Respectfully, Jackie”