Health Hint; Zinc depletes Copper...(zinc also causes tummy upsets...)

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Motor neuron disease associated with copper deficiency. Weihl CC

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tsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus> , Lopate G

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Department of Neurology, Washington University School of Medicine,

Campus Box 8111, 660 South Euclid Avenue, St. Louis, Missouri 63110,

USA.

Copper deficiency in humans is a rare cause of myeloneuropathy that

usually presents with a spastic ataxic gait, hyperreflexia, and distal

sensory loss similar to that seen in patients with subacute combined

degeneration. We describe three copper-deficient patients, two of whom

were referred with a presumptive diagnosis of amyotrophic lateral

sclerosis, who had progressive asymmetric weakness or electrodiagnostic

findings of proximal and distal denervation suggestive of lower motor

neuron disease. Copper replacement resulted in stabilization or mild

improvement in weakness. The clinical spectrum of human copper

deficiency should include lower motor neuron disease in addition to a

syndrome of spastic ataxia.

PMID: 16929546 [PubMed - indexed for MEDLINE]

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