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Great Plains Laboratory Needs Study Participants!

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The Great Plains Laboratory is seeking qualified individuals to participate

in a reference range study. We are looking for children and adults, (ages

2-83) to help us update or normal ranges for neuro-peptides and organic

acids in the urine. We especially need " normal " (or typical) children to

qualify for this study due to the fact that many of our patients are

children on the Autistic spectrum. Our goal is to test as many as 100

children age 2-13, (80 boys and 20 girls) and 100 individuals age 14-83,

(50% males and 50% females). The data we collect will be kept strictly

confidential and will only be used for medical and scientific purposes that

will not identify you or your child in any way.

Below is the list of qualified spaces left for this study and they will fill

up quickly. If you have or are acquainted with children that are clearly

qualified as " typical " (see FAQ's below), please contact ASAP to

reserve your place in the study because it is FIRST COME FIRST SERVE.

5 spaces for men ages 13-82

2 spaces for girls ages 2-6

30 spaces for boys ages 2-6

30 spaces for boys ages 7-12

We are offering ONE FREE Organic Acids Test Certificate (a $240.00 value)

for each qualified specimen we obtain for the study. This test offers the

most complete and accurate evaluation of certain opportunistic pathogens and

can determine certain vitamin deficiencies, problems in energy metabolism,

oxidative stress, and many other factors not routinely tested. The free

Organic Acid Test is good for 6 months and can be used for any person you

choose.

To qualify, the participant must fulfill the criteria for " normal " (or

typical) as defined by the parameters in the attached document and give

permission to use your results in this study. The data provided in this

study will be used to refine diagnostic testing which helps aid nutritional

approaches to the treatment of disease. All identifying information will be

removed from the final results and posted to our website

(www.greatplainslaboratory.com <http://www.greatplainslaboratory.com/> ).

Your participation is greatly appreciated. The more data we can collect,

the more meaningful our results will be. Please carefully read the

information attached and call Bonovich at 913-341-8949 or email at

jbonovich@... to see if spots are still available. Availability is

limited so please to not hesitate to call.

Thank you,

Lori Knowles

General Manager

New Beginnings Nutritionals

Frequently Asked Questions

How to I determine if an individual qualifies for the " normal " range study?

If the individual does NOT have the following::

* Individual with any form of autism, PDD and Aspergers Syndrome

* Individual with known genetic diseases such as PKU, Down's

syndrome, etc.

* Individual with serious medical conditions such as diabetes,

cancer, Tourette's syndrome, an autoimmune disease (i.e.; Lupus, Arthritis,

MS), Lyme Disease, Chronic Fatigue, Fibromyalgia, Irritable Bowel Syndrome,

Chronic Constipation/Diarrhea or seizures

* Individual being treated for any mental health issues such as

depression, anxiety, bi-polar, etc.

* Individual with significant developmental problems such as markedly

reduced height or weight, delayed speech or significant delay in motor

skills such as walking or running

* Individual with an infectious disease such as flu or ear infection

at the time of the test

* Individual with severe allergies including symptoms such as

migraine headaches, runny nose for a substantial period of time, dark

circles under the eyes, eczema, or red ears much of the time

* Individual with hyperactivity or attention deficit, significant

behavior problems such as extreme shyness or aggressive behavior

* Individual with a significant learning disability such as dyslexia

What do I receive for helping with this study?

You will receive a certificate for a FREE Organic Acid Test (OAT) for the

person or child of your choice ($240.00) value for every qualified sample

provided. You can submit more than one sample and you will receive a FREE

Organic Acid Test certificate for every qualifying submission. If the FREE

OAT is used on an individual with Autism, you will have the opportunity to

participate in an additional research study.

How can an Organic Acid Test be useful?

The Great Plains Laboratory Organic Acid Test (OAT) offers the most complete

and accurate evaluation of intestinal microorganisms, such as yeast and

bacteria. Abnormal toxic metabolites of these microorganisms can cause or

worsen behavior disorders, cause hyperactivity, aggressiveness and affect

energy levels and immune functioning. Deficiencies of vitamins,

antioxidants, amino acid metabolites or fatty acid metabolites evaluated in

the OAT can also affect the physical and psychological condition, cause

fatigue and make the patient more vulnerable to infections and viruses.

This Organic Acid Test may help determine the underlying conditions that may

be causing symptoms of the following illnesses: Anxiety, gastrointestinal

disorders, diarrhea or constipation, Fibromyalgia, depression, learning

difficulties, attention deficit disorders, recurrent infections, Alzheimer's

disease, chronic fatigue, colitis, Crohn's disease, Down's syndrome,

multiple sclerosis, endometriosis, AIDS, autism and other developmental

disorders. Treatments are recommended that may result in significant

improvement of symptoms.

Does the " normal " individual have to be in my family?

No. You can submit individuals from your extended family, friends or

neighbors and receive a FREE OAT certificate to use on any person you would

like. We would appreciate you sharing this information to other families in

the Kansas City area who can also benefit from the free Organic Acid Test.

Just remember, parents/caregivers must correctly read these instructions,

call to verify and reserve any open spots, follow all instructions and bring

the completed Questionnaire to The Great Plains Laboratory along with the

urine sample in order to qualify for a FREE test certificate.

Bonovich is the contact person for this study and can be reached at

913-341-8949 or jbonovich@....

Will any information be required for the person who is receiving the FREE

Organic Acid Test?

Yes, but only if the person receiving the free test is on the Autistic

Spectrum, which includes Individual with AD(H)D. We are also collecting

important data on these Individual and would like to use their test data to

add to another important research study. (Please see attached for more

information).We will ask you to fill out an accompanying form along with

permission to use the child's data for research purposes.

How do I receive the test kits?

Contact Bonovich at The Great Plains Laboratory (913-341-8949 or

lbonovich@...) and tell her the age and sex of the " normal " individual

that you want to participate in the study. If we are still accepting

individuals in the given age range, you will need to provide your mailing

address and phone number. For an individual in diapers, please request

pediatric urine collection bags to be included. We will mail the test kits

directly to your home at our expense. A study questionnaire will be

enclosed which will need to be completed and returned with each urine

sample. It is very important that you ONLY submit samples from individuals

for the normal range study that truly qualify and do not have any of the

issues listed on the previous page.

Are there any restrictions that have to be followed prior to collecting the

urine sample?

Yes. It is important that the individual in the study strictly avoid any

forms of apples, pears, grapes, raisins, cranberries, and their juices for a

full 24 hours preceding the urine collection. Soy proteins must be avoided

one full week prior to the study, (soy bean oil and soy lecithin are okay).

How do I collect and return the samples?

You will receive complete instructions on sample collection with each test

kit and also instructions on the food items that need to be avoided before

collecting the urine. It is important to collect the very first morning

urine which is the most concentrated urine of the day. If you are using

pediatric collection bags, an overnight collection is fine. Please read the

enclosed shipping instructions and return the specimen in the enclosed

pre-paid FedEx bag.

When and how will I receive the results?

The Organic Acid and Peptide Test results may take up 2-3 weeks receiving

the specimens.

Results will be mailed to you at the address provided.

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