THYROID AND CARDIOVASCULAR DISEASE (CVD)

[Guest guest]

DATE: January 16, 2002, Volume 15, Number 06

THIS WEEK'S STORIES

- MARCHING IN LOCKSTEP FASHION: THE THYROID AND THE HEART

- TESTING REVEALS EARLY " INVISIBLE " SIGNS OF THYROID DYSFUNCTION

- ESTROGEN METABOLISM EXPERT HIGHLIGHTED BY IFM PUBLICATION

<A HREF= " http:// " >http://www.gsdl.com/assessments/thyroid/</A>

Faulty Thyroid Metabolism Linked to Chronic Heart Failure

<A HREF= " http://www.gsdl.com/news/connections/vol13/conn20010808.html#story2 " >

http://www.gsdl.com/news/connections/vol13/conn20010808.html#story2</A>

Thyroid Dysfunction Linked to Elevated Cardiac Risk

<A HREF= " http://www.gsdl.com/news/connections/vol12/conn20010411.html#story1 " >

http://www.gsdl.com/news/connections/vol12/conn20010411.html#story1</A>

Sources: Napoli R, Biondi B, Guardasole V, Matarazzo M, Pardo F,

Angelini V, Fazio S, Sacca L. Impact of hyperthyroidism and its

correction on vascular reactivity in humans. Circulation

2001;104:3076-3080.

Petretta M, Bonaduce D, Spinelli L, Vicario MLE, Nuzzo V, Marciano F,

Camuso P, De Sanctis V, Lupoli G. Cardiovascular haemodynamics and

cardiac autonomic control in patients with subclinical and over

hyperthyroidism. Eur J Endocrinol 2001;145:691-696.

Thyroid Hormone Imbalances More Common Than Suspected

<A HREF= " http://www.gsdl.com/news/connections/vol11/conn20010228.html " >

http://www.gsdl.com/news/connections/vol11/conn20010228.html</A>

The Importance Of Being Earnest About Thyroid Autoimmunity

<A HREF= " http://www.gsdl.com/news/connections/vol14/conn20011121.html#story2 " >

http://www.gsdl.com/news/connections/vol14/conn20011121.html#story2</A>

Source: Stockigt JR. Case finding and screening strategies for

thyroid dysfunction. Clinica Chimica Acta 2002;315:111-124.

This Week's Lab Tidbit

- DR. THOMAS L. KLUG CHOSEN RESEARCHER OF THE MONTH

December proved to be a busy month for Dr. L. Klug, a primary

researcher in the area of cancer prevention and the president of

ImmunaCare Corporation, which developed the estrogen metabolism test

used with our Women's Hormonal Health Assessment. He addressed over

250 anti-aging practitioners at their winter meeting in Las Vegas,

and he recorded an interview with S. Bland, Ph.D., board

chairman of the Institute for Functional Medicine and editor of the

monthly audiotape newsletter Functional Medicine Update.

Dr. Bland took this special opportunity to bring subscribers up to

date on breaking developments in measurement of estrogen metabolism

and the new treatment alternatives made possible by advanced

assessments. According to Dr. Bland, this research suggests that

estrogen metabolites may have as great as if not greater influence on

an aging woman's physiology than the source hormones themselves.

Moreover, it is now becoming more widely understood that nutrition

and lifestyle changes can modify patterns of metabolism to improve a

woman's health outlook.

Although research linking estrogen metabolism dates back to the

1960s, only recently have research and development efforts by Dr.

Klug and his team made it possible to measure the downstream

metabolites 2-hydroxyestrone and 16alpha-hydroxyestrone accurately,

cost-effectively, and conveniently. ImmunaCare's most recent advance

is to develop the methodology for measuring these markers in a single

serum sample.

Concluding the interview, Dr. Klug underscored the potential of our

emerging understanding of estrogen metabolism. " This is probably as

important, " he explained, " as the breakthroughs that followed the

recognition of the different types of cholesterol and their effects

on heath. "

Dr. Klug's December lecture can be download in PDF format at

<A HREF= " http://www.gsdl.com/education/presentations/ " >

http://www.gsdl.com/education/presentations/</A> More information about

the Women's Hormonal Health Assessment is available online at

<A HREF= " http://www.gsdl.com/assessments/womenshealth/ " >

http://www.gsdl.com/assessments/womenshealth/</A>

Learn more about the work under way at the Institute for Functional

Medicine at <A HREF= " http://www.functionalmedicine.org " >

www.functionalmedicine.org</A>

Source: Bland JS. Researcher of the month: Klug, PhD.

Functional Medicine Update. 2001;21(12).