Re: Genes Role Small in Rheumatoid Arthritis

[Guest guest]

WHAT DOES THIS HAVE TO DO WITH SICK BUILDINGS AND TOXIC MOLD....PLEASE QUIT POSTING THIS STUFF THAT DOESN'T HAVE ANYTHING TO DO WITH OUR "CRUSADE". I AM NOT SAYING THAT THIS STUFF IS NOT IMPORTANT, BECAUSE I KNOW IT IS, BUT THIS IS SO REDICULOUS. IF I AM OFF BASE AND EVERYONE IN THIS SITE WANTS TO SEE THIS INFORMATION, THEN PLEASE TELL ME SO, AND I WILL QUIT COMPLAINING, AND I APOLOGIZE IF I HAVE OFFENDED ANYONE. ----- Original Message ----- From: Barbara Herskovitz Sent: Tuesday, February 05, 2002 4:32 AM Sick Buildings Information & Support Subject: [] Genes Role Small in Rheumatoid Arthritis Genes May Play Small Role in Rheumatoid Arthritis Fri Feb 1, 1:26 PM ET By Mulvihill NEW YORK (Reuters Health) - A small study involving twins suggests that a person's genes play only a minor role in whether or not they will develop rheumatoid arthritis--an autoimmune disease in which the body's tissues are mistakenly attacked by its own immune system. The potentially disabling disease, which affects 2.1 million Americans, causes chronic inflammation and pain of the joints. Even though scientists have been actively investigating rheumatoid arthritis, the cause of the disease is still unknown, according to the study's lead author, Dr. Anders J. Svendsen of Odense University Hospital in Denmark. "Infectious agents such as viruses, bacteria and fungi have long been suspected as causative agents, but none has been found to be responsible for the development of the disease," Svendsen told Reuters Health in an interview. "Many scientists believe that there exists an appreciable genetic component in the causation of the disease, but no single genetic factor has been proven as the cause of the disease," he added. To investigate, Svendsen and colleagues studied 13 identical and 36 fraternal (non-identical) twin pairs in which at least one twin had rheumatoid arthritis. In two of the fraternal twin pairs both siblings were affected, but in none of the identical twin pairs were both siblings affected, the researchers report in the February 2nd issue of British Medical Journal. "So even though (identical) twins have exactly the same genes, only one of the twins developed the disease," he explained. "Thus, our study shows that environmental effects seem to be of pivotal significance in the causation of rheumatoid arthritis, and contrasts the results from previous twin studies on rheumatoid arthritis which have pointed toward a role for the genes," Svendsen added. This study cannot disprove a genetic component in susceptibility to rheumatoid arthritis, Dr. Alan J. Silman of Manchester University Medical School, writes in an accompanying commentary. "However, their results emphasise that the genetic effects are weak compared with environmental ones in explaining differences in occurrence of the disease," Silman adds. SOURCE: British Medical Journal 2002;234:264-267. FAIR USE NOTICE:This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more information go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond 'fair use', you must obtain permission from the copyright owner.

[Guest guest]

,

Get a grip! If you don't want to read it hit delete. I do not want to see any info censored. We do not know all the potential connections to IAQ. The "crusade" can be very far reaching than what is on your horizon.

BTW, I do think your off base. Let the moderator be the filter. This IS America, if you don't want to read it hit delete.

Just my thoughts!

mark

On Tue, 5 Feb 2002 19:38:26 -0600 " Dayberry" <sdayberry@...> writes:

WHAT DOES THIS HAVE TO DO WITH SICK BUILDINGS AND TOXIC MOLD....PLEASE QUIT POSTING THIS STUFF THAT DOESN'T HAVE ANYTHING TO DO WITH OUR "CRUSADE". I AM NOT SAYING THAT THIS STUFF IS NOT IMPORTANT, BECAUSE I KNOW IT IS, BUT THIS IS SO REDICULOUS. IF I AM OFF BASE AND EVERYONE IN THIS SITE WANTS TO SEE THIS INFORMATION, THEN PLEASE TELL ME SO, AND I WILL QUIT COMPLAINING, AND I APOLOGIZE IF I HAVE OFFENDED ANYONE.

----- Original Message -----

From: Barbara Herskovitz

Sent: Tuesday, February 05, 2002 4:32 AM

Sick Buildings Information & Support

Subject: [] Genes Role Small in Rheumatoid Arthritis

Genes May Play Small Role in Rheumatoid Arthritis Fri Feb 1, 1:26 PM ET By Mulvihill NEW YORK (Reuters Health) - A small study involving twins suggests that a person's genes play only a minor role in whether or not they will develop rheumatoid arthritis--an autoimmune disease in which the body's tissues are mistakenly attacked by its own immune system.

The potentially disabling disease, which affects 2.1 million Americans, causes chronic inflammation and pain of the joints. Even though scientists have been actively investigating rheumatoid arthritis, the cause of the disease is still unknown, according to the study's lead author, Dr. Anders J. Svendsen of Odense University Hospital in Denmark. "Infectious agents such as viruses, bacteria and fungi have long been suspected as causative agents, but none has been found to be responsible for the development of the disease," Svendsen told Reuters Health in an interview. "Many scientists believe that there exists an appreciable genetic component in the causation of the disease, but no single genetic factor has been proven as the cause of the disease," he added. To investigate, Svendsen and colleagues studied 13 identical and 36 fraternal (non-identical) twin pairs in which at least one twin had rheumatoid arthritis. In two of the fraternal twin pairs both siblings were affected, but in none of the identical twin pairs were both siblings affected, the researchers report in the February 2nd issue of British Medical Journal. "So even though (identical) twins have exactly the same genes, only one of the twins developed the disease," he explained. "Thus, our study shows that environmental effects seem to be of pivotal significance in the causation of rheumatoid arthritis, and contrasts the results from previous twin studies on rheumatoid arthritis which have pointed toward a role for the genes," Svendsen added. This study cannot disprove a genetic component in susceptibility to rheumatoid arthritis, Dr. Alan J. Silman of Manchester University Medical School, writes in an accompanying commentary. "However, their results emphasise that the genetic effects are weak compared with environmental ones in explaining differences in occurrence of the disease," Silman adds. SOURCE: British Medical Journal 2002;234:264-267. FAIR USE NOTICE:This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more information go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond 'fair use', you must obtain permission from the copyright owner.

[Guest guest]

I agree with your comments, for if one is highly sensitive to sick building mold, could their immune system be weakened by heavy metal poisoning?, YES.

C. W.

----- Original Message -----

From: Mark Rakow

Sent: Wednesday, February 06, 2002 7:58 AM

Subject: Re: [] Genes Role Small in Rheumatoid Arthritis

,

Get a grip! If you don't want to read it hit delete. I do not want to see any info censored. We do not know all the potential connections to IAQ. The "crusade" can be very far reaching than what is on your horizon.

BTW, I do think your off base. Let the moderator be the filter. This IS America, if you don't want to read it hit delete.

Just my thoughts!

mark

On Tue, 5 Feb 2002 19:38:26 -0600 " Dayberry" <sdayberry@...> writes:

WHAT DOES THIS HAVE TO DO WITH SICK BUILDINGS AND TOXIC MOLD....PLEASE QUIT POSTING THIS STUFF THAT DOESN'T HAVE ANYTHING TO DO WITH OUR "CRUSADE". I AM NOT SAYING THAT THIS STUFF IS NOT IMPORTANT, BECAUSE I KNOW IT IS, BUT THIS IS SO REDICULOUS. IF I AM OFF BASE AND EVERYONE IN THIS SITE WANTS TO SEE THIS INFORMATION, THEN PLEASE TELL ME SO, AND I WILL QUIT COMPLAINING, AND I APOLOGIZE IF I HAVE OFFENDED ANYONE.

----- Original Message -----

From: Barbara Herskovitz

Sent: Tuesday, February 05, 2002 4:32 AM

Sick Buildings Information & Support

Subject: [] Genes Role Small in Rheumatoid Arthritis

Genes May Play Small Role in Rheumatoid Arthritis Fri Feb 1, 1:26 PM ET By Mulvihill NEW YORK (Reuters Health) - A small study involving twins suggests that a person's genes play only a minor role in whether or not they will develop rheumatoid arthritis--an autoimmune disease in which the body's tissues are mistakenly attacked by its own immune system.

The potentially disabling disease, which affects 2.1 million Americans, causes chronic inflammation and pain of the joints. Even though scientists have been actively investigating rheumatoid arthritis, the cause of the disease is still unknown, according to the study's lead author, Dr. Anders J. Svendsen of Odense University Hospital in Denmark. "Infectious agents such as viruses, bacteria and fungi have long been suspected as causative agents, but none has been found to be responsible for the development of the disease," Svendsen told Reuters Health in an interview. "Many scientists believe that there exists an appreciable genetic component in the causation of the disease, but no single genetic factor has been proven as the cause of the disease," he added. To investigate, Svendsen and colleagues studied 13 identical and 36 fraternal (non-identical) twin pairs in which at least one twin had rheumatoid arthritis. In two of the fraternal twin pairs both siblings were affected, but in none of the identical twin pairs were both siblings affected, the researchers report in the February 2nd issue of British Medical Journal. "So even though (identical) twins have exactly the same genes, only one of the twins developed the disease," he explained. "Thus, our study shows that environmental effects seem to be of pivotal significance in the causation of rheumatoid arthritis, and contrasts the results from previous twin studies on rheumatoid arthritis which have pointed toward a role for the genes," Svendsen added. This study cannot disprove a genetic component in susceptibility to rheumatoid arthritis, Dr. Alan J. Silman of Manchester University Medical School, writes in an accompanying commentary. "However, their results emphasise that the genetic effects are weak compared with environmental ones in explaining differences in occurrence of the disease," Silman adds. SOURCE: British Medical Journal 2002;234:264-267.