Grapefruit seed extract

[Guest guest]

NutriBiotic 'The Original GSE Liquid Concentrate " .

________________________________

From: low dose naltrexone on behalf of pghaworth

Sent: Tue 4/28/2009 1:15 PM

low dose naltrexone

Subject: [low dose naltrexone] Grapefruit Seed Extract

I was recommended to take Grapefruit Seed Extract by Dr. Sullivan. Can anyone

give me the name of a tried and true brand? Thanks for your help.

[Guest guest]

Careful with grapefruits (not sure about the seeds). Grapefruit interferes with an enzyme in the intestine and this does not allow the enzyme to breakdown any medication you are taking resulting in overdose. It can be dangerous. HaifaFrom: pghaworth <pghaworth@...>Subject: [low dose naltrexone] Grapefruit Seed Extractlow dose naltrexone Date: Tuesday, April 28, 2009, 11:15 AM

I was recommended to take Grapefruit Seed Extract by Dr. Sullivan. Can anyone give me the name of a tried and true brand? Thanks for your help.

[Guest guest]

Thank you . I bought this one. Sorry to be so long in replying but I am

very ill with the FM right now.

>

> NutriBiotic 'The Original GSE Liquid Concentrate " .

>

>

>

> ________________________________

>

> From: low dose naltrexone on behalf of pghaworth

> Sent: Tue 4/28/2009 1:15 PM

> low dose naltrexone

> Subject: [low dose naltrexone] Grapefruit Seed Extract

>

>

>

>

>

> I was recommended to take Grapefruit Seed Extract by Dr. Sullivan. Can anyone

give me the name of a tried and true brand? Thanks for your help.

>

[Guest guest]

Thank you for your reply. Since the GSE was prescribed by my LDN doctor and I am

on no other meds I feel very secure taking it. If there was an issue with the

LDN he wouldn't have told me to take it.

>

> Careful with grapefruits (not sure about the seeds). Grapefruit interferes

with an enzyme in the intestine and this does not allow the enzyme to breakdown

any medication you are taking resulting in overdose. It can be dangerous.

>

> Haifa

>

[Guest guest]

I haven't researched the components of Grapefruit Seed Extract, but the

following study may be relative, so it's worth noting:

The results of the study mentioned in the article below suggest it may not

be a good idea for anyone to take their medication with fruit juice -

better to space the two apart - either take juice long before, or long

after medication has had an opportunity to be metabolised.

' ... Scientists and consumers have known for years that grapefruit juice

can increase the absorption of certain drugs - with the potential for

turning normal doses into toxic overdoses. Now, the researcher who first

identified this interaction is reporting that grapefruit and other common

fruit juices, including orange and apple, can do the opposite effect by

substantially decreasing the absorption of other drugs, potentially wiping

out their beneficial effects. ... '

G. , Ph.D., Professor of clinical pharmacology, University of

Western Ontario in London, Ontario

August 2008

I've included the article further below in case it's of interest.

Kind regards,

Cris

Fruit Juice boosts & negates medications

New reasons to avoid grapefruit and other juices when taking certain drugs

Tuesday, August 19, 2008, PHILADELPHIA

Scientists and consumers have known for years that grapefruit juice can

increase the absorption of certain drugs - with the potential for turning

normal doses into toxic overdoses. Now, the researcher who first identified

this interaction is reporting that grapefruit and other common fruit

juices, including orange and apple, can do the opposite effect by

substantially decreasing the absorption of other drugs, potentially wiping

out their beneficial effects.

The study provides a new reason to avoid drinking grapefruit juice and

these other juices when taking certain drugs, including some that are

prescribed for fighting life-threatening conditions such as heart disease,

cancer, organ-transplant rejection, and infection, the researcher says.

These findings - representing the first controlled human studies of this

type of drug-lowering interaction - were described today at the 236th

National Meeting of the American Chemical Society.

" Recently, we discovered that grapefruit and these other fruit juices

substantially decrease the oral absorption of certain drugs undergoing

intestinal uptake transport, " says study leader G. , Ph.D., a

professor of clinical pharmacology with the University of Western Ontario

in London, Ontario. " The concern is loss of benefit of medications

essential for the treatment of serious medical conditions. "

and colleagues announced almost 20 years ago the unexpected finding

that grapefruit juice can dramatically boost the body's levels of the

high-blood-pressure drug felodipine, causing potentially dangerous effects

from excessive drug concentrations in the blood. Since then, other

researchers have identified nearly 50 medications that carry the risk of

grapefruit-induced drug-overdose interactions. As a result of the so-called

" Grapefruit Juice Effect, " some prescription drugs now carry warning labels

against taking grapefruit juice or fresh grapefruit during drug

consumption.

In the most recent research, 's group had healthy volunteers take

fexofenadine, an antihistamine used to fight allergies. The volunteers

consumed the drug with either a single glass of grapefruit juice, water

containing only naringin (substance in grapefruit juice that gives the

juice its bitter taste), or water. When fexofenadine was taken with

grapefruit juice, only half of the drug was absorbed compared to taking the

drug with water alone, says. Loosing half the amount of drugs taken

into the body can be critical for certain drugs, he points out.

They also showed that the active ingredient of grapefruit juice, naringin,

appears to block a key drug uptake transporter, called OATP1A2, involved in

shuttling drugs from the small intestine to the bloodstream. Blocking this

transporter reduces drug absorption and neutralizes their potential

benefits, the researchers say. By contrast, drugs whose levels are boosted

in the presence of grapefruit juice appear to block an important drug

metabolizing enzyme, called CYP3A4, that normally breaks down drugs.

" This is just the tip of the iceberg, " says. " I'm sure we'll find

more and more drugs that are affected this way. "

To date, grapefruit, orange and apple juices have been shown to lower the

absorption of etoposide, an anticancer agent; certain beta blockers

(atenolol, celiprolol, talinolol) used to treat high blood pressure and

prevent heart attacks; cyclosporine, a drug taken to prevent rejection of

transplanted organs; and certain antibiotics (ciprofloxacin, levofloxacin,

itraconazole). But more drugs are likely to be added to the list as

physicians become more aware of this drug-lowering interaction,

says.

Orange and apple juices also appear to contain naringin-like substances

that inhibit OATP1A2, says. The chemical in oranges appears to be

hesperidin, but the chemical in apples has not yet been identified, the

researchers notes.

advises patients to consult with their doctor or pharmacist before

taking any medications with grapefruit juice or other fruits and juices.

Unless it is known to be a problem, he recommends taking most medications

only with water. This research was funded by grants from the Canadian

Institutes of Health Research and the United States Public Health Service.

The American Chemical Society - the world's largest scientific society - is

a nonprofit organization chartered by the U.S. Congress and a global leader

in providing access to chemistry-related research through its multiple

databases, peer-reviewed journals and scientific conferences. Its main

offices are in Washington, D.C., and Columbus, Ohio.

For full information about the Philadelphia meeting, including access to

abstracts of more than [TC] scientific papers and hundreds of non-technical

summaries, visit http://www.acspresscenter.org.

The paper on this research, TOXI 030, was presented on Tuesday, August 19,

during the symposium, Drug Safety.

G. , Ph.D., is a professor of clinical pharmacology at the

University of Western Ontario in London, Ontario.

3a. Grapefruit Seed Extract

Posted by: " pghaworth " pghaworth@... pghaworth

Date: Thu May 7, 2009 8:32 am ((PDT))

I have diagnosed FM. My LDN prescribing doctor told me I needed to take

Grapefruit Seed Extract, per label instructions, for a yeast problem while

taking the LDN. I am 6 days out with the GSE and 5 days out with the LDN. I

have some questions please.

1. I am taking 15 drops, 1 time a day with the GSE. Is this enough or too

much? Label said 5-15 drops, 1-3 times a day.

2. How long do I take the GSE and how will I know when I'm " cured " of the

yeast.

3. Any other things I can do to speed the elimination of the yeast so the

LDN will help?

I have eliminated sugar, dairy, wheat products, etc. Money is an issue so

if it's expensive it's off the table. Thanks for your help.

3c. Re: Grapefruit Seed Extract

Posted by: " pghaworth " pghaworth@... pghaworth

Date: Thu May 7, 2009 8:53 am ((PDT))

Thank you for your reply. Since the GSE was prescribed by my LDN doctor and

I am on no other meds I feel very secure taking it. If there was an issue

with the LDN he wouldn't have told me to take it.

Careful with grapefruits (not sure about the seeds). Grapefruit interferes

with an enzyme in the intestine and this does not allow the enzyme to

breakdown any medication you are taking resulting in overdose. It can be

dangerous.

Haifa

[Guest guest]

Cris

Grapefruit and Grapefruit Seed Extract (GSE) are two very different things. GSE has anitmicrobial action.

mjh

www.ldn-help.com <--- get LDN brochure, find a doc, see our faces, hear Bradley, watch videos...

===========

Remember Mom this Mother's Day! Find a florist near you now.

[Guest guest]

> Hi Dana,

> What is the highest dosage of GSE(liquid) could give to my 22 kilograms child?

How would I know I have given the right dose alreaday?

I am hesitant to write how much liquid GSE I have given my son, or myself for

that matter. Suffice to say it was a LOT of GSE. Adding biotin allowed me to

reduce the GSE, but it was still a LOT.

Too much GSE caused major diarrhea here, so that was my clue that it was too

much. Otherwise, i gave as much GSE/Biotin as my son [and myself] needed to

eliminate the yeast problem.

Dana

[Guest guest]

Hi Dana,How long did you use GSE? Are there any known side effects after long

use? Does it kill useful bacteria in the gut? I like how it works for systemic

yest but I am looking for some alternative (ooo or garlic oil may be...) as we

are only at round 3 of ALA chelation and it is a long way ahead...Thanks a lot

for sharing your experience!Thank you Mel for your reply...Marina

10a. Re: grapefruit seed extract

    Posted by: " danasview "  danasview@... danasview

    Date: Wed Nov 11, 2009 7:04 am ((PST))

> Hi Dana,

> What is the highest dosage of GSE(liquid) could give to my 22 kilograms

child?  How would I know I have given the right dose alreaday?

I am hesitant to write how much liquid GSE I have given my son, or myself for

that matter.  Suffice to say it was a LOT of GSE.  Adding biotin allowed me to

reduce the GSE, but it was still a LOT.

Too much GSE caused major diarrhea here, so that was my clue that it was too

much.  Otherwise, i gave as much GSE/Biotin as my son [and myself] needed to

eliminate the yeast problem.

Dana

[Guest guest]

> Hi Dana,How long did you use GSE?

Probably 6 years.

>>Are there any known side effects after long use?

Same as from any use. It can slow down phase I liver function, and it can cause

bad bacteria if you give it when the yeast is gone.

>>Does it kill useful bacteria in the gut?

Yes

>>I like how it works for systemic yest but I am looking for some alternative

(ooo or garlic oil may be...) as we are only at round 3 of ALA chelation and it

is a long way ahead...

OoO will kill off good bacteria also.

In my experience, nothing beat the combination of biotin and GSE for the rapid

elimination of yeast overgrowth.

Dana

[Guest guest]

Hi, Sorry for jumping in here, but am having trouble figuring out ds's yeasty

behaviours...2-3 weeks ago, I gave ds 6 drops GSE twice a day over 2 days..he

then became very lethargic and 'dopey', all his yeasty behaviour left and for a

while I though I had gotten rid of the yeast, as his mushy stool had gone and

became sort of greyish looking, soft, but formed and 'sinks to the bottom' of

the bowl..I have no idea whether this has to do with liver function or not...Now

he is back to his yeasty behaviour, but worse..lots of hysterical laughter and

no attention, running up the hallway and running his hands over everything he

walks past...anyway, do you think he now has a bacterial problem(maybe I went

too far with the GSE)...Should I give something like OLE to see what happens

concerning his behaviour?..And I have read somewhere that ACV needs to be the

right acidity(I've been giving 'Melrose'-5.6% acidity) and am wondering whether

it's making him acidic

instead of alkaline.  How well does something like Coconut oil and yeast

specific enzymes really work(I've been giving CandiZyme capsules mixed with

water and syringed but don't know whether it would work as well(he won't take

capsules). 

Donna.

Mum to C-5. ASD

             J-9.  NT

________________________________

From: danasview <danasview@...>

Sent: Fri, 13 November, 2009 12:54:50 AM

Subject: [ ] Re: grapefruit seed extract

 

> Hi Dana,How long did you use GSE?

Probably 6 years.

>>Are there any known side effects after long use?

Same as from any use. It can slow down phase I liver function, and it can cause

bad bacteria if you give it when the yeast is gone.

>>Does it kill useful bacteria in the gut?

Yes

>>I like how it works for systemic yest but I am looking for some alternative

(ooo or garlic oil may be...) as we are only at round 3 of ALA chelation and it

is a long way ahead...

OoO will kill off good bacteria also.

In my experience, nothing beat the combination of biotin and GSE for the rapid

elimination of yeast overgrowth.

Dana

________________________________________________________________________________\

__

Win 1 of 4 Sony home entertainment packs thanks to 7.

Enter now: http://au.docs./homepageset/

[Guest guest]

Hi Dana and others,

I tried putting liquid GSE into an empty capsule so my son could take it, as the

bitterness is hard to mask. I have only used up to 2 drops. However each time

he has tried it (not many) he complains of a stomach ache. Do you think it's

because it's not diluted before it enters his digestive tract or is this a side

effect you've seen?

Thanks!

PJ

[Guest guest]

This has happened to us every time we tried to use GSE on an empty stomach. My

son complained of burning in his stomach. So when we do give GSE, we do it with

food.

Satia

>

> Hi Dana and others,

>

> I tried putting liquid GSE into an empty capsule so my son could take it, as

the bitterness is hard to mask. I have only used up to 2 drops. However each

time he has tried it (not many) he complains of a stomach ache. Do you think

it's because it's not diluted before it enters his digestive tract or is this a

side effect you've seen?

>

> Thanks!

>

> PJ

>

[Guest guest]

>>Now he is back to his yeasty behaviour, but worse..lots of hysterical laughter

and no attention, running up the hallway and running his hands over everything

he walks past...anyway, do you think he now has a bacterial problem(maybe I went

too far with the GSE)...

At my house, this would be yeast coming back. Try giving the GSE with biotin.

This combination was very effective at my house. Plus, the biotin helped with

long-term yeast control.

Dana

[Guest guest]

> Hi Dana and others,

> I tried putting liquid GSE into an empty capsule so my son could take it, as

the bitterness is hard to mask. I have only used up to 2 drops. However each

time he has tried it (not many) he complains of a stomach ache. Do you think

it's because it's not diluted before it enters his digestive tract or is this a

side effect you've seen?

This happens if I give it on an empty stomach. Give it with food, see if that

helps.

Dana

[Guest guest]

We use the capsule form with no problems. We open the capsule and mix it in

juice or milk.

TJ

________________________________

From: pjthreeboys <patricia@...>

Sent: Fri, November 13, 2009 3:13:55 AM

Subject: [ ] Re: grapefruit seed extract

 

Hi Dana and others,

I tried putting liquid GSE into an empty capsule so my son could take it, as the

bitterness is hard to mask. I have only used up to 2 drops. However each time he

has tried it (not many) he complains of a stomach ache. Do you think it's

because it's not diluted before it enters his digestive tract or is this a side

effect you've seen?

Thanks!

PJ

[Guest guest]

Thank you, Dana!

[Guest guest]

Thanks Dana...I have been giving his GSE in the morning and then again around 4

hours before his nightly probiotics(which contain his Biotin)...I will now give

his GSE and then straight after give his Biotin(can only mix this in water and

syringe---Will this method be ok?).

Donna.

________________________________

From: danasview <danasview@...>

Sent: Sat, 14 November, 2009 1:38:00 AM

Subject: [ ] Re: grapefruit seed extract

 

>>Now he is back to his yeasty behaviour, but worse..lots of hysterical laughter

and no attention, running up the hallway and running his hands over everything

he walks past...anyway, do you think he now has a bacterial problem(maybe I went

too far with the GSE)...

At my house, this would be yeast coming back. Try giving the GSE with biotin.

This combination was very effective at my house. Plus, the biotin helped with

long-term yeast control.

Dana

________________________________________________________________________________\

__

Win 1 of 4 Sony home entertainment packs thanks to 7.

Enter now: http://au.docs./homepageset/

[Guest guest]

Just wanted to mention - you could be seeing a phenol reaction too.  You're

giving a hefty dose of GSE and it's highly phenolic.  Phenol and yeast

behaviors look similar.

________________________________

From: Donna Bowerman <donna12345au@...>

Sent: Sat, November 14, 2009 5:09:16 AM

Subject: Re: [ ] Re: grapefruit seed extract

 

Thanks Dana...I have been giving his GSE in the morning and then again around 4

hours before his nightly probiotics(which contain his Biotin)...I will now give

his GSE and then straight after give his Biotin(can only mix this in water and

syringe---Will this method be ok?).

Donna.

____________ _________ _________ __

From: danasview <danasview (DOT) com>

Sent: Sat, 14 November, 2009 1:38:00 AM

Subject: [ ] Re: grapefruit seed extract

 

>>Now he is back to his yeasty behaviour, but worse..lots of hysterical laughter

and no attention, running up the hallway and running his hands over everything

he walks past...anyway, do you think he now has a bacterial problem(maybe I went

too far with the GSE)...

At my house, this would be yeast coming back. Try giving the GSE with biotin.

This combination was very effective at my house. Plus, the biotin helped with

long-term yeast control.

Dana

____________ _________ _________ _________ _________ _________ _

Win 1 of 4 Sony home entertainment packs thanks to 7.

Enter now: http://au.docs. / homepageset/

[Guest guest]

> Thanks Dana...I have been giving his GSE in the morning and then again around

4 hours before his nightly probiotics(which contain his Biotin)...I will now

give his GSE and then straight after give his Biotin(can only mix this in water

and syringe---Will this method be ok?).

I have given GSE and biotin together for quite a few years. It should be fine.

Dana

[Guest guest]

Hi,

1) Can grapefruit seed extract (GSE) be given together with probiotics ? Or we

do need to space out the timing ?

2) Can GSE be given together with enzymes (such as DigestGold, Glutenease,

Candidase, Virastop) ? Or we need to space out the timing ?

3) Should GSE be given on empty stomach or with food ?

Regards,

Anne

[Guest guest]

I just order Kirkman Grapefruit Seed Extract to help my son with some yeast

issues.

I would like to know how are you given grapefruit seed extract to help  fight

yeast?

Do you give before or after a meal? It says in the label to be careful if you

take prescription medication my son take Prozac to help him would that be

problem.I will ask his pediatrician about this  too.

Thanks!!

A.Simon,  

" I know God promises not to give me more than I can handle.

 I just wish he didn't trust me so much. " -Mother

[Guest guest]

You give it whenever. Just never with probiotics, it should be 4 or more hours

away from them.

It's not a problem with prozac.

The ped won't know anything about using grapefruit seed for yeast.

They tell you to avoid citrus with certain things like thyroid meds and

something else I can't recall but not with Prozac.

Start slow on the dose. Increase slow so his die off is tolerable.

Consider adrenal fatigue if he's on Prozac or low thyroid function. Often those

drugs are prescribed when the real problem is their adrenals/thyroids.

Jan

>

> I just order Kirkman Grapefruit Seed Extract to help my son with some yeast

issues.

> I would like to know how are you given grapefruit seed extract to help  fight

yeast?

> Do you give before or after a meal? It says in the label to be careful if you

take prescription medication my son take Prozac to help him would that be

problem.I will ask his pediatrician about this  too.

> Thanks!!

>

>

>

> A.Simon,  

> " I know God promises not to give me more than I can handle.

>  I just wish he didn't trust me so much. " -Mother

>

>

>

>

>

>

>

[Guest guest]

In a message dated 09/01/2010 18:42:41 GMT Standard Time,

asimon100@... writes:

I just order Kirkman Grapefruit Seed Extract to help my son with some

yeast issues.

I would like to know how are you given grapefruit seed extract to help

fight yeast?

Do you give before or after a meal? It says in the label to be careful if

you take prescription medication my son take Prozac to help him would that

be problem.I will ask his pediatrician about this too.

>>I think SSRI's are one of the contraidications for GSE which slows down

phase 1 of liver detox and may cause a build up of the drug in the system.

Best to check with Kirkman

HTH

Mandi in UK

[Guest guest]

Grapefruit in general is high in phenols.

GSE is known to be high in phenols.

dgfindley wrote:

>

> Hi all, wondering if anyone knows if GSE is bad for our kids that are

> sensative to phenols?

>

> the nutribiotic products says the following which made me wonder:

>

> a natural quaternary compound synthesized from the seed and pulp of

> certified organically grown grapefruit. The grapefruit bioflavonoids

> (polyphenolics) are converted into an extremely potent compound that

> has been proven highly effective in numerous applications.

>

> deborah

>

>

[Guest guest]

> Hi all, wondering if anyone knows if GSE is bad for our kids that are

sensative to phenols?

It is high phenol. When my son had phenol issues, I had to give GSE with

No-Fenol enzyme.

Dana