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This is an interesting discussion. I also have no joint destruction

visible on the x-rays, but are on mtx. When I asked my doctor why, she said

it was to prevent other joint to become infected. So it is supposed to slow

down (stop?) the process I guess. But the stupid thing about that is that

you ever know if it works, since the process is not stopped (in my case),

but maybe slowed down. So when are you ever supposed to get off of this

medication.

Does anybody know more about this?

ELiane

At 05:04 PM 7/21/99 EDT, you wrote:

>From: BRANCHSHAW@...

>

>Subj: Re: [ ] NSAIDS vs. DMARDS

>Date: 7/21/99 1:38:15 PM CST

>From: CTNATIVE@...

>Reply-to: onelist

> onelist

>

>>From: CTNATIVE@...

>>

>>Dear Jim,

>>My laymans understanding of the reasoning for going on DMARDS is that they

>>stop the joint destruction. NSAIDS do not - they merely help with the pain

>>and inflammation.

>

>

>Dear ,

>

>What's odd in my case is that over the last four years I've had MRI's on:

>1. My left knee;

>2. Both hands and wrists; and

>3. On my right shoulder.

>In each case it was determined that I had no visible joint destruction

>despite the pain and inflammation. Since I've exhausted the NSAID pool as

>far as pain and inflammation is concerned, are DMARDS the next typical step

>for pain relief even without present joint destruction?

>

>Thanks again,

>Jim

>

>

>---------------------------

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That is a good question. Unlike you my back, neck, hands and feet all show

destruction, among several other body parts.

How about the tendons and ligaments - are they showing up on the test - or

only bone?

The pain is a big issue, but since there is no joint destruction going on, I

would question the diagnosis with my MD before going on DMARDS. You sure are

sharp!

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You can stop the methotrexate anytime to

see for yourself if a flare occurs. However, there is always the risk that

it will not work the next time you start it.

This is a big risk, since it is a really good choice for drugs for PA.

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