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Sent: Friday, January 11, 2002 5:40 AM

Subject: Important - Studies Will Take Sept. 11's Measure in Health Effects

> January 11, 2002

>

> Studies Will Take Sept. 11's Measure in Health Effects

> By KIRK JOHNSON

> Public health researchers in New York, struggling to determine the real

> dimensions of the health threat at the World Trade Center site, are

> beginning an ambitious series of long-term studies to identify and then

> track a wide range of people who lived through the nightmare of dust,

smoke

> and stress when the towers fell.

>

> Two Manhattan hospitals, for instance, are collecting blood samples from

> pregnant women who say they were in the vicinity of the trade center on

the morning of Sept. 11 or in the days afterward. Mount Sinai School of

Medicine will send out 3,000 letters to obstetricians in the region as early

as

next week, also seeking pregnant women who were near ground zero for a related

study that will look at the possible effects of maternal anxiety as well

as toxic substances in the air.

Beginning next Monday, physicians and investigators from Queens College

will start searching for nonunion day laborers, many of them now dispersed

into the work force, who helped clean up dust-saturated buildings around the

trade center in the weeks just after the attacks. The New York Academy of

Medicine is beginning an even more ambitious task: building a registry of

every person — from the firefighters to members of the New York City Transit

tunnel crews — who worked, even for a day, at ground zero.

> The researchers say that while these studies are, in certain respects, the

> sort of work that invariably follows major disasters and accidents, they

> also say that the variety of the inquiries reflects a disturbing but

> ever-growing realization among health experts: four months after the

> attacks, very little can be said with scientific certainty about the

health

> risks that recovery workers or bystanders faced in the disaster and the

> cleanup.

>

> That uncertainty, which some health and environmental experts now say was

> perhaps not adequately reflected by public officials in the days and weeks

> after the attacks, underscores how unique the World Trade Center disaster

> was as a public health emergency.

>

> The blast of dust and smoke — and the toxic substances, fibers and ash

that

> blew through New York in the days afterward — is without precedent in

> medical literature, which means that there are no studies to fall back on

> for guidance on whether to be alarmed or reassured.

>

> The air-monitoring system that was set up after the attacks — indeed, the

> whole science of air monitoring — is based chiefly on long- term exposures

> associated with ordinary air pollution or workplace hazards. This means

that

> the effects of short, intense bursts of pollution — the sort experienced

by

> many thousands of people on Sept. 11 — are far less known.

>

> " There are gaps in our knowledge base, " said Dr. Frederica P. Perera, a

> professor of public health at Columbia, who is leading one of the prenatal

> projects.

>

> Professor Perera said that based on the evidence already reported, she

does

> not expect to find widespread health consequences in her prenatal study.

The

> air-quality measurements for things like asbestos, PCB's and dioxins,

taken

> in the neighborhoods around the World Trade Center, have consistently

shown

> little cause for worry about long-term health.

>

> But as a scientist, she cannot offer any definitive reassurances when an

> anxious resident or downtown office worker calls. " Because of the

> uncertainty, and the paucity of the data, it's important to lay to rest

the

> anxieties, " she said. " And we'd like to be able to provide reassurance

based

> on data. "

>

> Some $10.5 million was made available by the federal government alone this

> week to finance medical and health studies and worker environmental

training

> related to Sept. 11.

>

> Studies like these are intensely complicated, a difficulty compounded in

New

> York by the demographics of an area where residents, tourists and office

> workers — many of them commuters — are mixed together. No one has any idea

> how many pregnant women, for example, were downtown on Sept. 11. The

> Columbia study is seeking 300 of them — some more exposed to the ash and

> dust, some less — while Mount Sinai is hoping for another 300, with some

> overlap likely between the two.

>

> Cleanup workers, many of them immigrants who do not belong to labor

unions,

> have gone on to other jobs and may be impossible to find. One cleanup

> company that had 1,800 workers two weeks after the attacks now has 50,

> according to Dr. Markowitz, director of the Center for the Biology

of

> Natural Systems, an environmental and occupational health research

institute

> at Queens College, which is leading the search for those workers.

>

> Dr. Markowitz said his mobile examination vehicle, to be parked near City

> Hall, will have a physician, a breathing-test technician and an

interviewer,

> all of them fluent in Spanish, the language spoken by most of the cleanup

> crews. He said that part of his motivation in starting the study is the

> issue of economic disadvantage.

>

> " These guys are about the least likely group to get any medical

attention, "

> he said. " They either don't have access to health care, or will go to a

> neighborhood doctor who doesn't have a clue about toxins. "

>

> Even defining what " exposed " means has required rigorous new methodology.

> The Mount Sinai study, for example, has identified three zones around

ground

> zero, each of which — based on existing air monitoring — will figure in

the

> analysis.

>

> Meanwhile, researchers at the University of Medicine and Dentistry of New

> Jersey and at the Lamont-Doherty Earth Observatory at Columbia are working

> on pinpointing where the smoke plume went in the days immediately after

the

> attack. In this way, a zone of exposure in, say, Brooklyn Heights, which

was

> downwind just after the attacks, might be better compared to one in

TriBeCa

> in Manhattan.

>

> Other approaches are more fine- tuned. The Mount Sinai study is focusing

on

> women who were in Lower Manhattan on Sept. 11 itself, and within that

group

> is only really seeking women who were south of Chambers Street, a few

blocks

> from the trade center. The Columbia study, by contrast, is seeking women

who

> were downtown on the day of the attacks or in the days afterward, but it

> draws a line three miles around ground zero, beyond which a woman is

> considered " unexposed. "

>

> Some of the researchers say that the accumulated work, when it is

complete,

> will also provide a demographic, sociological bonus: the first full human

> portrait of New York on the morning it was transformed — who was where,

what

> they saw and felt, what they breathed.

>

> For at least the prenatal studies, there is the loud ticking of the

> biological clock. The women being sought must have been pregnant on Sept.

> 11, which leaves only five months more or so for them to be found.

>

> " This is not going to be easy, " said Gertrud S. Berkowitz, a professor in

> the Department of Community and Preventive Medicine at the Mount Sinai

> School of Medicine.

>

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