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Hello there,

Just a quick note to introduce ourselves. Our son, , was diagnosed with

pre-B ALL last week. We are still awaiting the results of the cytogenetics. We

are fortunate to live in an area with an excellent childrens hospital (Cook

Childrens in Fort Worth). Our Day 8 bone marrow aspiration is scheduled for

this Thursday, 9/17. We should find out the results of the cytogenetics that

day as well.

He has Down Syndrome and his ALL was caught with a screening CBC. His RBC and

WBC counts were normal, but his platelets were low (50K). According to the

initial biopsy his marrow was 90% affected (whatever that means). His initial

blast count was 3700, and his blast count at day 4 (or 5?) was 1100. His

chemistry labs were good enough that they allowed us to go home until his Day 8

procedure.

For induction we are currently signed up for a COG research study, AALL033. We

will definitely need to examine the options available to us for Consolidation.

We are nervous about choosing the most correct arm of the study.

We look forward to conversing with you folks over the next several years!

Craig and Jeanne

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