Guest guest Posted April 17, 2002 Report Share Posted April 17, 2002 To All: I asked Doug to give his 2 cents on some questions I had seen recently on the group. Below are his thoughts. Hope they can help. This was his reply to me. I don't know that he posts to the group these days.Beverly Weikert BEVERLY/ALL: There are five types of antibody testing: IgA, IgD, IgE, IgM, IgG. IgA protects the mucus membranes in the respiratory and GI tracts against invasion by microorganisms and activates the complement system. It includes antitoxins, antibacterial agglutinins, antinuclear antibodies and allergic reactions. IgA exists in its secretory form in colostrum, saliva, tears, and in GI and bronchial secretions. IgD is present in serum and umbilical cord blood. Its function is unknown. However, increased values are reported in chronic infections, connective tissue disorders, certain lever (joint-related) diseases, and IgD myeloma. Decreased values occur in hereditary and acquired immune deficiency syndromes. IgE is present in serum and interstitial fluid. It has antibody activity for hypersensitivity reactions. Increased values occur in atopic skin diseases (eczema), parasitic infestations, hay fever, asthma, anaphylalactic shock, and IgE myeloma. IgG has antibody activity against viruses, some bacteria, fungi, and toxins. It occurs as a secondary response after IgM and is the only immunoglobulin that crosses the placenta. (Normal indication is for long-term/high levels of multiple mold/yeast species exposures.) IgG also has indicator activity of subclass proteins as IgG1, IgG2, IgG3, and IgG4 which fall within various normal ranges. Ranges that are out of the norm are usually indicators of associated with primary immunodeficiencies, and can indicate mold antibody exposures relative to certain infections. IgM is the first antibody to appear after antigenic stimulation. It produces antibody against rheumatoid factors and graham negative (mostly bacterium) organisms, forms the ABO blood group, and activates the complement system. "Complement system" one of 11 complex, enzymatic serum proteins. In an antigen-antibody reaction, complement causes lysis (destruction or dissolution of a cell or molecule), and is also involved in other physiologic reactions, including anaphylaxis and phagocytosis. This extracted by Mosby's Medical Dictionary 4th Edition, Clinical Laboratory Tests, 2nd Edition, Springhouse Books Hope this helps explain. God Bless you and your health. Doug Haney, Environmental Health Research/Writer (Author: "Toxic Mold! Toxic Enemy!" and companion article "The Deadly Side of Fungal Exposure") E-mail: Healthrights@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 17, 2002 Report Share Posted April 17, 2002 Beverly, Thanks so much for posting this information for all and Thanks to Doug too. You are a wealth of imformation and glad to have you as our Public Relations Supervisor. NTMC --- Beverly Weikert <weikert004@...> wrote: > > To All: I asked Doug to give his 2 cents on some > questions I had seen recently on the group. Below > are his thoughts. Hope they can help. This was his > reply to me. I don't know that he posts to the > group these days. > > Beverly Weikert > > > > BEVERLY/ALL: There are five types of antibody > testing: IgA, IgD, IgE, IgM, IgG.IgA protects the > mucus membranes in the respiratory and GI tracts > against invasion by microorganisms and activates the > complement system. It includes antitoxins, > antibacterial agglutinins, antinuclear antibodies > and allergic reactions. IgA exists in its secretory > form in colostrum, saliva, tears, and in GI and > bronchial secretions.IgD is present in serum and > umbilical cord blood. Its function is unknown. > However, increased values are reported in chronic > infections, connective tissue disorders, certain > lever (joint-related) diseases, and IgD myeloma. > Decreased values occur in hereditary and acquired > immune deficiency syndromes.IgE is present in serum > and interstitial fluid. It has antibody activity > for hypersensitivity reactions. Increased values > occur in atopic skin diseases (eczema), parasitic > infestations, hay fever, asthma, anaphylalactic > shock, and IgE myeloma.IgG has antibody activity > against viruses, some bacteria, fungi, and toxins. > It occurs as a secondary response after IgM and is > the only immunoglobulin that crosses the placenta. > (Normal indication is for long-term/high levels of > multiple mold/yeast species exposures.) IgG also > has indicator activity of subclass proteins as IgG1, > IgG2, IgG3, and IgG4 which fall within various > normal ranges. Ranges that are out of the norm are > usually indicators of associated with primary > immunodeficiencies, and can indicate mold antibody > exposures relative to certain infections.IgM is the > first antibody to appear after antigenic > stimulation. It produces antibody against > rheumatoid factors and graham negative (mostly > bacterium) organisms, forms the ABO blood group, and > activates the complement system. " Complement system " > one of 11 complex, enzymatic serum proteins. In an > antigen-antibody reaction, complement causes lysis > (destruction or dissolution of a cell or molecule), > and is also involved in other physiologic reactions, > including anaphylaxis and phagocytosis.This > extracted by Mosby's Medical Dictionary 4th Edition, > Clinical Laboratory Tests, 2nd Edition, Springhouse > BooksHope this helps explain. God Bless you and > your health. Doug Haney, Environmental Health > Research/Writer (Author: " Toxic Mold! Toxic Enemy! " > and companion article " The Deadly Side of Fungal > Exposure " ) E-mail: Healthrights@... > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
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