MULTIPLE OP Pesticide Residues house and vehicle dust

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Quite a mixture of cholinesterase inhibitors being inhaled daily wouldn't you

agree...........

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_u

ids=11878617 & dopt=Abstract

1: J AOAC Int 2002 Jan-Feb;85(1):36-43

Size exclusion chromatographic cleanup for GC/MS determination of

organophosphorus pesticide residues in household and vehicle dust.

Moate TF, Furia M, Curl C, Muniz JF, Yu J, Fenske RA.

University of Washington, Environmental Health Laboratory, Seattle

98195-7234, USA. tmoate@...

Size exclusion chromatography (SEC) was used as a cleanup method for the

analysis of organophosphorus pesticides in household and vehicle dusts. The

pesticides investigated were:

1.diazinon

2.methyl parathion

3. chlorpyrifos

4. malathion

5. phosmet

6. azinphosmethyl

These compounds are of interest due to their use in agricultural tree fruit

production and/or urban pest control. Pesticides were determined via gas

chromatography/mass spectrometry with selected-ion monitoring and cool

on-column injection. The lower limit of method validation was 0.20 microg/g.

Method limits of detection in dust ranged from 0.012-0.055 microg/g. Dust

samples were collected with vacuums from the homes and vehicles of people

living and working in a rural agricultural region in the central part of

Washington State. The analytes were extracted from the dust by sonication in

acetone. The extracts were solvent-exchanged to cyclohexane, frozen, thawed,

and centrifuged prior to SEC injection. Following SEC, the eluent was split

into 2 fractions, concentrated, and injected on-column into the gas

chromatograph. This method represents the first complete publication

describing the SEC cleanup of organophosphorus pesticides in dusts.

Recoveries of pesticides in dusts ranged from 63.5-110.8 +/- 4.9-19.6% over a

fortification range of 0.20-10.00 microg/g. This optimized, automated, and

reproducible SEC method does not require further treatment or cleanup for

trace determination of these organophosphorus pesticides.

PMID: 11878617 [PubMed - in process]