Guest guest Posted May 6, 2000 Report Share Posted May 6, 2000 <A HREF= " http://www.genentech.com/products/herceptin/insert.html#warnings " >Ge nentech, Inc.: HERCEPTIN® (Trastuzumab)</A> " Carcinogenesis: HERCEPTIN has not been tested for its carcinogenic potential. " Know why not? Because you don't want to know it's carcinogenic potential. Do you feel that the FDA should do these tests? Do you feel that it is my responsibility to do these tests if I am to effectively evaluate this drug? Why do you expect others to accept these test results? " ...However, HER2 protein expression is high in many embryonic tissues including cardiac and neural tissues; in mutant mice lacking HER2, embryos died in early gestation... An increased incidence of anemia and leukopenia was observed in the treatment group receiving HERCEPTIN and chemotherapy, especially in the HERCEPTIN and AC subgroup, compared with the treatment group receiving chemotherapy alone. " Side-effects revealed in the study: " Pain, asthenia, fever, chills, headache, abdominal pain, back pain, infection, flu syndrome, accidental injury, allergic reaction, tachycardia, congestive heart failure, nausea, diarrhea, vomiting, anorexia, anemia, leukopenia, peripheral edema, edema, bone pain, arthralgia, insomnia, dizziness, paresthesia, depression, peripheral neuritis, neuropathy, cough increased, dyspnea, rhinitis, pharyngitis, sinusitis, rash, herpes simplex, acne, urinary tract infection...... " " WARNINGS Cardiotoxicity Signs and symptoms of cardiac dysfunction, such as dyspnea, increased cough, paroxysmal nocturnal dyspnea, peripheral edema, S3 gallop, or reduced ejection fraction, have been observed in patients treated with HERCEPTIN® (Trastuzumab). Congestive heart failure associated with HERCEPTIN therapy may be severe and has been associated with disabling cardiac failure, death, and mural thrombosis leading to stroke... " " There have been no formal drug interaction studies performed with HERCEPTIN in humans. " This is what it is made of: " Chinese Hamster Ovary cell proteins " " Other serious adverse events The following other serious adverse events occurred in at least one of the 958 patients treated with HERCEPTIN: Body as a Whole: cellulitis, anaphylactoid reaction, ascites, hydrocephalus, radiation injury, deafness, amblyopia Cardiovascular: vascular thrombosis, pericardial effusion, heart arrest, hypotension, syncope, hemorrhage, shock arrhythmia Digestive: hepatic failure, gastroenteritis, hematemesis, ileus, intestinal obstruction, colitis, esophageal ulcer, stomatitis, pancreatitis, hepatitis Endocrine: hypothyroidism Hematological: pancytopenia, acute leukemia, coagulation disorder, lymphangitis Metabolic: hypercalcemia, hypomagnesemia, hyponatremia, hypoglycemia, growth retardation, weight loss Musculoskeletal: pathological fractures, bone necrosis, myopathy Nervous: convulsion, ataxia, confusion, manic reaction Respiratory: apnea, pneumothorax, asthma, hypoxia, laryngitis Skin: herpes zoster, skin ulceration Urogenital: hydronephrosis, kidney failure, cervical cancer, hematuria, hemorrhagic cystitis, pyelonephritis " This just in: <A HREF= " http://www.genentech.com/products/herceptin/herceptin-safety.pdf " >http:/ /www.genentech.com/products/herceptin/herceptin-safety.pdf</A> Number of negative side-effects experienced in my family of six using the herbal cleanses recommended in Hulda's books: ZERO (0). Foggs Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.