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This is freaky because I quit smoking to get my implants!

----- Original Message -----

From: " Kathi " <pureheart@...>

Sent: Saturday, September 28, 2002 10:22 AM

Subject: PATCHING UP

> PATCHING UP

>

> Health Sciences Institute e-Alert

>

> September 28, 2002

>

> Dear Reader,

>

> Brad successfully kicked a long-time cigarette smoking habit

> in June of 1990. As with most everyone who quits smoking, he

> was looking forward to improved health in return for his hard

> won victory. Instead, just five weeks later, he was diagnosed

> with multiple sclerosis.

>

> Right from the beginning, Brad had a hunch that the sudden

> appearance of the MS symptoms was somehow connected to his

> break with cigarettes. But when he opened the subject with

> his doctor and other healthcare professionals, his hunch was

> always dismissed as illogical. I mean, how could there be ANY

> downside with kicking the habit, right?

>

> Then in 1998, Brad picked up a copy of the Wall Street

> Journal and read an article about R.J. Reynolds Tobacco

> Company scientists who were studying the effects of nicotine

> on central nervous system (CNS) diseases such as Parkinson's

> disease, Alzheimer's disease, and MS.

>

> Seems they wouldn't have thought Brad's hunch was so

> illogical.

>

> --------------------------------------------------------------

> Central nervous mysteries

> --------------------------------------------------------------

>

> When Brad read the Wall Street Journal article in '98, he

> didn't need to consult any doctors or researchers. He began

> using an over-the-counter nicotine patch immediately. The

> patch helped improve the mobility in his hands and upper

> body, but after a couple of years became less effective and

> he stopped using it. He now feels strongly that if he had

> started using the patch when he was first diagnosed, he would

> have been able to have more control over the symptoms. But he

> doubts that the infusion of nicotine could have helped to

> significantly change the course of the disease.

>

> Nicotine therapy. Those are two words I never expected to see

> side by side. But there are a number of research projects

> currently underway that, if successful, could one day bring

> nicotine into the mainstream as a therapy to help control

> various CNS disease symptoms.

>

> I've noticed, however, that MS is mentioned in discussions of

> nicotine therapy infrequently. References to Parkinson's

> disease, Alzheimer's disease, Tourette's syndrome, attention-

> deficit hyperactivity disorder, and depression are the most

> common health issues likely to be successfully treated with

> nicotine. Brad believes that the complexity of MS may be the

> reason it's often left off that list. With Parkinson's

> disease, for instance, researchers have a clearer idea about

> the mechanism of the disease - where it originates in the

> brain, and how it responds to treatments. Comparatively, MS

> is an enigma - far more difficult to understand and treat.

>

> --------------------------------------------------------------

> Into the maze

> --------------------------------------------------------------

>

> So at this point, what is known about nicotine and its effect

> on disorders of the central nervous system?

>

> Start with acetylcholine, a biochemical neurotransmitter that

> creates nerve impulses in neurons. For the nervous system and

> muscles to function properly, acetylcholine has to find

> special receptors in the neurons. One of those receptors is

> called a nicotinic receptor, and it responds to both

> acetylcholine and nicotine. When nicotine is introduced into

> the system, the number of nicotinic receptors increases.

> Alzheimer's patients, for instance, are believed to suffer

> from a loss of nicotrinic receptors. This impairs nerve

> impulses, resulting in memory lapses and problems with other

> brain functions.

>

> More than two decades ago, research at town University

> showed that nicotine can also protect neurons against damage

> and death. The problem is that nicotine affects a wide

> variety of neurotransmitter systems. So while it may be doing

> good things in some areas, it also increases blood pressure

> and heart rate. This is one reason why quite a bit of

> nicotine research is focused on the development of nicotine

> formulas designed to be selective in their effects on the

> different varieties of nicotinic receptors.

>

> Which is much easier said than done. It's as if researchers

> were electricians, sorting through tens of thousands of

> individual circuits, looking for the one that performs a very

> specific task, and then trying to enhance that single circuit

> without affecting any of the others. But as daunting as that

> research might be, it continues in earnest, because if a

> synthetic nicotine that targets a single type of receptor can

> be developed, it can also be patented. That's why a number of

> major pharmaceutical companies are currently devoting huge

> resources toward the development of a nicotine drug.

>

> Something tells me this will not be the last e-Alert on this

> topic.

>

> --------------------------------------------------------------

> No smoking

> --------------------------------------------------------------

>

> If Brad had not successfully quit smoking on that June day in

> 1990, he would still have developed multiple sclerosis. He

> might have delayed the onset, but eventually it would have

> overcome the effect of the nicotine. Which brings us to two

> important points emphasized by the handful of researchers who

> have been studying nicotine for more than 20 years: 1)

> Nicotine may help treat CNS diseases, but it cannot cure

> them; and 2) This research should not in any way be taken as

> an endorsement of tobacco smoking. Without question, the

> negative effects of smoking far outweigh any positive effects

> that nicotine might have.

>

> ...and another thing

>

> Well, sometimes it happens.

>

> The September issue of the HSI Members Alert featured an

> article titled, " Omega-3 fatty acids: Panacea or poison for

> prostate patients? " written by Myers, M.D. The text

> refers to the " risks of glucosamine. " Instead, that sentence

> SHOULD have read, " risks of chondroitin sulfate. " There is

> absolutely no evidence that glucosamine contributes to the

> risk or growth of prostate cancer.

>

> Supplements containing chondroitin sulfate and glucosamine,

> two essential parts of cartilage, have been shown to slow and

> even reverse osteoarthritis, a degenerative joint disease.

> But while chondroitin sulfate may offer hope for arthritis

> patients, Dr. Myers has found convincing evidence that it can

> trigger prostate cancer growth and cause the cancer to spread

> to other sites.

>

> We apologize to our members and to Dr. Myers for any

> confusion created by this error.

>

> Dr. Myers is the Editor-in-Chief of " Prostate Forum " and the

> founder of the American Institute for Disease of the Prostate

> in Charlottesville, VA. For more information about his clinic

> and publications, call 434-974-1303, or log onto

> www.prostateforum.com.

>

> To Your Good Health,

>

>

> Health Sciences Institute

>

> Sources:

> " Researchers Hope to turn Lemon into Lemonade " Tabitha M.

> Powledge, BioMedNet News, 8/21/02

> " Nicotine Therapy Helps Parkinson's " Damian Carrington, BBC

> News, 2/21/00

> " A Good Side to Nicotine? New Treatments for

> Neurodegenerative Disorders may Emerge " Harvey Black, The

> Scientist, 2000

> " All About Multiple Sclerosis " mult-sclerosis.org

>

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