Guest guest Posted June 19, 2008 Report Share Posted June 19, 2008 I take and advise my anti-aging patients to take 300mg of ® ALA daily; for my cancer patients I recommmend 600mg (which is what was used in the study comparable to the IV) for three weeks and then take several weeks' break and then resume. I corresponded with Dr. Berkson (who is delightful and helpful) to get details of the IV protocol for ALA that he uses with oral LDN and he mentioned he has even more data coming out soon about this protocol. That someone has survived advanced pancreatic cancer for 4 years and seems to be in good health is like a miracle to me. Dr. JM --- low dose naltrexone wrote: --------------------------------- Low Dose Naltrexone Low Dose Naltrexone Messages In This Digest (25 Messages) 1a. Rx of Pancreatic Cancer with LDN and ALA From: JAQUELYN MCCANDLESS 1b. Re: Rx of Pancreatic Cancer with LDN and ALA From: Mirian Arcila 1c. Need advice on Prednisone weaning and if I should hold the LDN for t From: Walter Hoffmann 1d. Re: Rx of Pancreatic Cancer with LDN and ALA From: Etta Reece 2a. Re: Need advice on Prednisone weaning and if I should hol... From: marshiris@... 2b. Re: Need advice on Prednisone weaning and if I should hol... From: Walter Hoffmann 2c. Re: Need advice on Prednisone weaning and if I should hol... From: mdsport85@... 2d. Re: Need advice on Prednisone weaning and if I should hol... From: marshiris@... 3a. Re: Pancreatic cancer From: Etta Reece 3b. Re: Pancreatic cancer From: Etta Reece 4a. infor guys please From: MarcMorh@... 4b. Re: infor guys please From: Art 4c. Re: infor guys please From: Joni Fernino 5. Russert death raises questions From: mdsport85@... 6a. ps.. also need more infor also i live in florida From: MarcMorh@... 6b. Re: ps.. also need more infor also i live in florida From: Joni Fernino 7a. how long does ldn take to work? From: emailit2004 7b. Re: how long does ldn take to work? From: livinwithcrohns 7c. Re: how long does ldn take to work? From: slenzrph@... 7d. Re: how long does ldn take to work? From: Art 8a. ALPHA LIPOIC ACID From: marshiris@... 8b. Re: ALPHA LIPOIC ACID From: Art 9a. LDN and MS From: lentams 10. ldn for ms, doctors in San Diego? From: k.bender10 11. Anyone taking over 5mg From: annaisa24 View All Topics | Create New Topic Messages 1a. Rx of Pancreatic Cancer with LDN and ALA Posted by: " JAQUELYN MCCANDLESS " JMcCandless@... jaquelynmccandless Wed Jun 18, 2008 2:01 am (PDT) For those who may not have access to IV ALA or a doctor to administer it, this article talks about use of oral form that is as effective as the IV form. ALPHA-LIPOIC ACID ® Topic: Plasma Pharmacokinetics of R-Lipoic Acid Keywords: PHARMACOKINETICS - Alpha-Lipoic Acid, R-Lipoic Acid, Racemic, Rac-LA, RLA, Sodium Salt, Potassium Salt, Na, K Reference: " The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects, " Carlson DA, AR, et al, Altern Med Rev, 2007; 12(4): 343-51. (Address: GeroNova Research, Inc., 4677 Meade St, Richmond, California 94804, USA. E-mail: david@... ). Summary: In this study, the pharmacokinetics of R-lipoic acid in humans were investigated. In one experiment, 12 subjects were orally administered 600 mg RLA (as NaRLA based on the RLA content) dissolved in 200 mL purified water 3-4 hours after a light meal. This was not found to have any adverse effects on plasma RLA levels. In a second experiment, 1 subject was given 3 doses of RLA (600 mg each), at 0, 15, and 30 minutes. This resulted in a Cmax of 21.9 mcg/mL, AUC of 1,049 mcg/min/mL, and extended the Tmax to 45 minutes. Interestingly, the authors state, " An unexpected finding of this study was that, at plasma concentrations as high as 30 mcg/mL…negligible free RLA was detected. " The authors conclude, " As anticipated from the preliminary study, NaRLA is less prone to polymerization, completely soluble in water, and displays significantly higher Cmax and AUC values and decreased time to maximum concentration (Tmax) and T1 & #47;2 values than RLA or rac-LA. In order to significantly extend Cmax and AUC, it is possible to administer three 600-mg RLA doses (as NaRLA) at 15-minute intervals to achieve plasma concentrations similar to those from a slow (20-minute) infusion of LA. This is the first study to report negligible unbound RLA even at the highest achievable plasma concentrations. " Also, see Life Extension's new Super ® ALA; I am recommending this along with LDN for a patient with metastatic cancer in Turkey whose doctor will not consider Dr. Berkson's protocol and who is unwilling to go the chemotherapy route. Dr. JM Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (4) 1b. Re: Rx of Pancreatic Cancer with LDN and ALA Posted by: " Mirian Arcila " mirianarcila@... Wed Jun 18, 2008 4:43 am (PDT) Thank you so much . You brought answer to my prayers. Mirian low dose naltrexone@...: JMcCandless@...: Wed, 18 Jun 2008 02:01:44 -0700Subject: [low dose naltrexone] Rx of Pancreatic Cancer with LDN and ALA For those who may not have access to IV ALA or adoctor to administer it, this article talks about useof oral form that is as effective as the IV form.ALPHA-LIPOIC ACID ®Topic: Plasma Pharmacokinetics of R-Lipoic Acid Keywords: PHARMACOKINETICS - Alpha-Lipoic Acid,R-Lipoic Acid, Racemic, Rac-LA, RLA, Sodium Salt,Potassium Salt, Na, K Reference: " The plasma pharmacokinetics ofR-(+)-lipoic acid administered as sodium R-(+)-lipoateto healthy human subjects, " Carlson DA, AR, etal, Altern Med Rev, 2007; 12(4): 343-51. (Address:GeroNova Research, Inc., 4677 Meade St, Richmond,California 94804, USA. E-mail: david@... ). Summary: In this study, the pharmacokinetics ofR-lipoic acid in humans were investigated. In oneexperiment, 12 subjects were orally administered 600mg RLA (as NaRLA based on the RLA content) dissolvedin 200 mL purified water 3-4 hours after a light meal.This was not found to have any adverse effects onplasma RLA levels. In a second experiment, 1 subjectwas given 3 doses of RLA (600 mg each), at 0, 15, and30 minutes. This resulted in a Cmax of 21.9 mcg/mL,AUC of 1,049 mcg/min/mL, and extended the Tmax to 45minutes. Interestingly, the authors state, " Anunexpected finding of this study was that, at plasmaconcentrations as high as 30 mcg/mL…negligible freeRLA was detected. " The authors conclude, " Asanticipated from the preliminary study, NaRLA is lessprone to polymerization, completely soluble in water,and displays significantly higher Cmax and AUC valuesand decreased time to maximum concentration (Tmax) andT1 & #47;2 values than RLA or rac-LA. In order tosignificantly extend Cmax and AUC, it is possible toadminister three 600-mg RLA doses (as NaRLA) at15-minute intervals to achieve plasma concentrationssimilar to those from a slow (20-minute) infusion ofLA. This is the first study to report negligibleunbound RLA even at the highest achievable plasmaconcentrations. " Also, see Life Extension's new Super ® ALA; I amrecommending this along with LDN for a patient withmetastatic cancer in Turkey whose doctor will notconsider Dr. Berkson's protocol and who is unwillingto go the chemotherapy route. Dr. JM Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (4) 1c. Need advice on Prednisone weaning and if I should hold the LDN for t Posted by: " Walter Hoffmann " redspot321@... redspot321 Wed Jun 18, 2008 4:45 am (PDT) Im currently on 7.5mg of pred Everyday. I take 5 in the morning and 2.5 at bedtime. Question- Should my next step be 2.5 in the am AND 2.5 in the pm or just 5mg in the am once a day? I only have 5mg tabs. Also, Im scheduled for food allergy testing. Should I not take the LDN the night before so my immune ststem is not boosted and responds to the allergen and the test results are not skewed, Thanks! Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (4) 1d. Re: Rx of Pancreatic Cancer with LDN and ALA Posted by: " Etta Reece " degolfers22@... degolfers22 Wed Jun 18, 2008 1:06 pm (PDT) What dosage do you recommend of the Super ® ALA? Should we stick with Life Expension's brand? Etta [low dose naltrexone] Re: Pancreatic cancer Etta, I'm sorry to hear about your brother. This web site (Thanks to Dudley) will tell you about the use of LDN and Alpha-lipoic acid. The person went into remission and back to work. TinyURL.com/ 2pwqy3 Betty Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (16) 4a. infor guys please Posted by: " MarcMorh@... " MarcMorh@... Wed Jun 18, 2008 9:16 am (PDT) if u get on the probiotics to clear up yeast .. what do u use to help keep u regular as the probiotics are now tending to constipate m e .a year ago i only tried ldn for a few weeks as it seemed to make my eyes dryer,, herpes worse but inflamation pain better .. i have severe chemical senditivity and as the weather has gotten hotter i seem to stinketh .. wether its chemicals or candida i dont know ..i also have ms symptoms,, pretty severe .. i had called dr ayer a year ago got a script for one month .. would like to try it again ..but cant afford start up fee .. any suggestions and..can u suggest different fillers and other suggestions on anything .. thanks donna ************** Gas prices getting you down? Search AOL Autos for fuel-efficient used cars. (http://autos.aol.com/used?ncid=aolaut00050000000007) Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 4b. Re: infor guys please Posted by: " Art " rtee54@... rtee54 Wed Jun 18, 2008 10:24 am (PDT) I believe a severe yeast problem can also cause constipation. Art -- > > is 300 mgs. a day enough for alpha?? i take 3 - 100 mg. tabs a day. should > this be increased?? > > _marshiris@..._ (mailto:marshiris@...) > > crohn's diesease - 17 years > LDN - 1 YEAR > > > > **************Gas prices getting you down? Search AOL Autos for > fuel-efficient used cars. (http://autos.aol.com/used? ncid=aolaut00050000000007) > Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 9a. LDN and MS Posted by: " lentams " lentams@... lentams Wed Jun 18, 2008 12:24 pm (PDT) Hello, I have a MS for 4 years. I would like to know how long it takes before results are seen? Thank you, Svetlana Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (15) 10. ldn for ms, doctors in San Diego? Posted by: " k.bender10 " k.bender10@... k.bender10 Wed Jun 18, 2008 2:51 pm (PDT) My wife has ms and is interested in ldn as a treatment. We've just moved to San Diego area and are trying to find a doctor who prescribes ldn for ms. Any suggestions? 760 707 2997 Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) 11. Anyone taking over 5mg Posted by: " annaisa24 " annaisa24@... annaisa24 Wed Jun 18, 2008 2:59 pm (PDT) I have been taking LDN for Ehlers Danlos and Fibromyalgia for about 4-5 months now. I started at 4.5 mg did see some improvement even though it took several months. I had seen some people say they were taking 5 mg so I decided to try it out. That helped the pain much more than at 4.5 mg. I am tempted to try 5.5 mg but I have not heard of anyone taking this dose and dont want to cause any harm. I have always seemed to have very high tolerences for medicine and dont know if this also applies to LDN for me? Thanks for any thoughts you may have. Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) Recent Activity 47 New Members Visit Your Group Health Healthy Aging Improve your quality of life. Meditation and Lovingkindness A Group to share and learn. Finance It's Now Personal Guides, news, advice & more. Need to Reply? Click one of the " Reply " links to respond to a specific message in the Daily Digest. Create New Topic | Visit Your Group on the Web Messages MARKETPLACE --------------------------------- users, check out this limited time offer from Blockbuster! Rent DVDs free for a month! Change settings via the Web ( ID required) Change settings via email: Switch delivery to Individual | Switch format to Traditional Visit Your Group | Groups Terms of Use | Unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2008 Report Share Posted June 19, 2008 Oh my God! That is so exciting to hear. I truly believe that we can beat this pancreatic cancer. Thank you so much for this information and most of all for the good news!!Etta [low dose naltrexone] Re: Pancreatic cancer Etta, I'm sorry to hear about your brother. This web site (Thanks to Dudley) will tell you about the use of LDN and Alpha-lipoic acid. The person went into remission and back to work. TinyURL.com/ 2pwqy3 Betty Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (16) 4a. infor guys please Posted by: "MarcMorhaol (DOT) com" MarcMorhaol (DOT) com Wed Jun 18, 2008 9:16 am (PDT) if u get on the probiotics to clear up yeast .. what do u use to help keep u regular as the probiotics are now tending to constipate m e .a year ago i only tried ldn for a few weeks as it seemed to make my eyes dryer,, herpes worse but inflamation pain better .. i have severe chemical senditivity and as the weather has gotten hotter i seem to stinketh .. wether its chemicals or candida i dont know ..i also have ms symptoms,, pretty severe .. i had called dr ayer a year ago got a script for one month .. would like to try it again ..but cant afford start up fee .. any suggestions and..can u suggest different fillers and other suggestions on anything .. thanks donna ************ ** Gas prices getting you down? Search AOL Autos for fuel-efficient used cars. (http://autos. aol.com/used? ncid=aolaut00050 000000007) Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 4b. Re: infor guys please Posted by: "Art" rtee54 (DOT) com rtee54 Wed Jun 18, 2008 10:24 am (PDT) I believe a severe yeast problem can also cause constipation. Art -- > > is 300 mgs. a day enough for alpha?? i take 3 - 100 mg. tabs a day. should > this be increased?? > > _marshiris@. .._ (mailto:marshiris@ ...) > > crohn's diesease - 17 years > LDN - 1 YEAR > > > > ************ **Gas prices getting you down? Search AOL Autos for > fuel-efficient used cars. (http://autos. aol.com/used? ncid=aolaut00050000 000007) > Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 9a. LDN and MS Posted by: "lentams" lentams (DOT) com lentams Wed Jun 18, 2008 12:24 pm (PDT) Hello, I have a MS for 4 years. I would like to know how long it takes before results are seen? Thank you, Svetlana Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (15) 10. ldn for ms, doctors in San Diego? Posted by: "k.bender10" k.bender10 (DOT) com k.bender10 Wed Jun 18, 2008 2:51 pm (PDT) My wife has ms and is interested in ldn as a treatment. We've just moved to San Diego area and are trying to find a doctor who prescribes ldn for ms. Any suggestions? 760 707 2997 Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) 11. Anyone taking over 5mg Posted by: "annaisa24" annaisa24 (DOT) . com annaisa24 Wed Jun 18, 2008 2:59 pm (PDT) I have been taking LDN for Ehlers Danlos and Fibromyalgia for about 4-5 months now. I started at 4.5 mg did see some improvement even though it took several months. I had seen some people say they were taking 5 mg so I decided to try it out. That helped the pain much more than at 4.5 mg. I am tempted to try 5..5 mg but I have not heard of anyone taking this dose and dont want to cause any harm. I have always seemed to have very high tolerences for medicine and dont know if this also applies to LDN for me? Thanks for any thoughts you may have. Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) Recent Activity 47 New Members Visit Your Group Health Healthy Aging Improve your quality of life. Meditation and Lovingkindness A Group to share and learn. Finance It's Now Personal Guides, news, advice & more. Need to Reply? Click one of the "Reply" links to respond to a specific message in the Daily Digest. Create New Topic | Visit Your Group on the Web Messages MARKETPLACE ------------ --------- --------- --- users, check out this limited time offer from Blockbuster! Rent DVDs free for a month! Change settings via the Web ( ID required) Change settings via email: Switch delivery to Individual | Switch format to Traditional Visit Your Group | Groups Terms of Use | Unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2008 Report Share Posted June 19, 2008 Oh my God! That is so exciting to hear. I truly believe that we can beat this pancreatic cancer. Thank you so much for this information and most of all for the good news!!Etta [low dose naltrexone] Re: Pancreatic cancer Etta, I'm sorry to hear about your brother. This web site (Thanks to Dudley) will tell you about the use of LDN and Alpha-lipoic acid. The person went into remission and back to work. TinyURL.com/ 2pwqy3 Betty Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (16) 4a. infor guys please Posted by: "MarcMorhaol (DOT) com" MarcMorhaol (DOT) com Wed Jun 18, 2008 9:16 am (PDT) if u get on the probiotics to clear up yeast .. what do u use to help keep u regular as the probiotics are now tending to constipate m e .a year ago i only tried ldn for a few weeks as it seemed to make my eyes dryer,, herpes worse but inflamation pain better .. i have severe chemical senditivity and as the weather has gotten hotter i seem to stinketh .. wether its chemicals or candida i dont know ..i also have ms symptoms,, pretty severe .. i had called dr ayer a year ago got a script for one month .. would like to try it again ..but cant afford start up fee .. any suggestions and..can u suggest different fillers and other suggestions on anything .. thanks donna ************ ** Gas prices getting you down? Search AOL Autos for fuel-efficient used cars. (http://autos. aol.com/used? ncid=aolaut00050 000000007) Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 4b. Re: infor guys please Posted by: "Art" rtee54 (DOT) com rtee54 Wed Jun 18, 2008 10:24 am (PDT) I believe a severe yeast problem can also cause constipation. Art -- > > is 300 mgs. a day enough for alpha?? i take 3 - 100 mg. tabs a day. should > this be increased?? > > _marshiris@. .._ (mailto:marshiris@ ...) > > crohn's diesease - 17 years > LDN - 1 YEAR > > > > ************ **Gas prices getting you down? Search AOL Autos for > fuel-efficient used cars. (http://autos. aol.com/used? ncid=aolaut00050000 000007) > Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (3) 9a. LDN and MS Posted by: "lentams" lentams (DOT) com lentams Wed Jun 18, 2008 12:24 pm (PDT) Hello, I have a MS for 4 years. I would like to know how long it takes before results are seen? Thank you, Svetlana Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (15) 10. ldn for ms, doctors in San Diego? Posted by: "k.bender10" k.bender10 (DOT) com k.bender10 Wed Jun 18, 2008 2:51 pm (PDT) My wife has ms and is interested in ldn as a treatment. We've just moved to San Diego area and are trying to find a doctor who prescribes ldn for ms. Any suggestions? 760 707 2997 Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) 11. Anyone taking over 5mg Posted by: "annaisa24" annaisa24 (DOT) com annaisa24 Wed Jun 18, 2008 2:59 pm (PDT) I have been taking LDN for Ehlers Danlos and Fibromyalgia for about 4-5 months now. I started at 4.5 mg did see some improvement even though it took several months. I had seen some people say they were taking 5 mg so I decided to try it out. That helped the pain much more than at 4.5 mg. I am tempted to try 5.5 mg but I have not heard of anyone taking this dose and dont want to cause any harm. I have always seemed to have very high tolerences for medicine and dont know if this also applies to LDN for me? Thanks for any thoughts you may have. Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (1) Recent Activity 47 New Members Visit Your Group Health Healthy Aging Improve your quality of life. Meditation and Lovingkindness A Group to share and learn. Finance It's Now Personal Guides, news, advice & more. Need to Reply? Click one of the "Reply" links to respond to a specific message in the Daily Digest. Create New Topic | Visit Your Group on the Web Messages MARKETPLACE ------------ --------- --------- --- users, check out this limited time offer from Blockbuster! Rent DVDs free for a month! Change settings via the Web ( ID required) Change settings via email: Switch delivery to Individual | Switch format to Traditional Visit Your Group | Groups Terms of Use | Unsubscribe Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2008 Report Share Posted June 19, 2008 I wonder if Swayze's doctors at Standford are aware of these amazing results for pancreatic cancer. ??? I saw news that he was responding well to his treatment, but of course they didn't say what his treatment was. Jann Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 19, 2008 Report Share Posted June 19, 2008 Conerning Swayze - It would also be interesting to know how large his tumor was, if it was one or multiple, or the location. I think all these factors determine the longevity outcomes of pancreatic CA. Once again, like many other cancers, the faster you get to treatment the better shot you have. Unfortunately, as we have seen over and over, pancreatic CA is pretty far along before symptoms show up. There are a few lesions that are resectable, and occasionally a whipple procedure is in order to insure all the tumor is resected. That can be a lifesaver but rare. I think we have not heard all the details of the Swayze condition, and am reluctant to be predictive of the outcome. But it goes to show us that even a healthy athletic guy can fall victim. I cannot stress enough that we should be hopeful but realistic about pancreatic cancer. The combination of ALA and LDN would be MY first choice in therapies, since all the other traditional methods really do not have a high incidence of success at all. I suspect radiation can help reduce the tumor size, but of course wonder if this would interfere with the actions of ALA or LDN at the cellular level. Besides, radiation has it's own nasty side effects and I would have to really think it over....Just my two cents.. Bob Cjannz2 <jbreslin@...> wrote: I wonder if Swayze's doctors at Standford are aware of theseamazing results for pancreatic cancer. ???I saw news that he was responding well to his treatment, but of coursethey didn't say what his treatment was.Jann Quote Link to comment Share on other sites More sharing options...
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