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how long does ldn take to work?

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I would like to know how long it takes before results are seen?

Do you need to take it a certain number of days before you know if

its going to work?

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I guess it depends what you're taking it for. Seems those with Crohn's

Disease see positive results fairly quickly. I have MS and am happy

disease progression has slowed/halted. Not everyone's experiences

symptom relief, this is considered a bonus.

Art

--

>

> I would like to know how long it takes before results are seen?

> Do you need to take it a certain number of days before you know if

> its going to work?

>

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Hi ,

There are a small percentage of people that have gotten out of the wheel

chair. Bill , Jim Garvin, and others as well. It is not something

to hope for, but there is always the small possibility. No one knows until

they try it and give it some time. Bill was in the chair and breathing

oxygen 24/7 and how he is landscaping for a living. He did not feel

anything for a little while and then he gradually got better and better.

Jim was using canes to get around when in the house. He needed the wheel

chair for any longer trecks. His first morning he did not need either one

again.

My best

Aletha

[low dose naltrexone] Re: how long does ldn take to work?

>- You may not experience " results " except no progression or, slowing

> down of symptoms. I have not seen or heard of anyone getting out of

> a wheelchair but, I guess it can happen. I'm happy with the

> stopping, slowing down of MS. Have you read the LDN website? It

> would answer most of your questions.

>

>

>

>

> -- In low dose naltrexone , " Art " <rtee54@...> wrote:

>>

>> I guess it depends what you're taking it for. Seems those with

> Crohn's

>> Disease see positive results fairly quickly. I have MS and am

> happy

>> disease progression has slowed/halted. Not everyone's experiences

>> symptom relief, this is considered a bonus.

>>

>> Art

>> --

>>

>>

>> >

>> > I would like to know how long it takes before results are seen?

>> > Do you need to take it a certain number of days before you know

> if

>> > its going to work?

>> >

>>

>

>

>

> ------------------------------------

>

>

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GARY - that's my concensus, exactly!! one statement does not negate the other, that dr. skip said!! LDN WORKS WHETHER OR NOT YOU LOSE SLEEP!!

marshiris@...

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RACHEL - i'd like that question answered, also!! what crohnie was CURED & no longer needed LDN any more??

marshiris@...

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Depends on what condition you have and your individual body. Remember also that

the aim of LDN is only to slow or stop progression, so any actual improvement is

a bonus! Therefore depending on your condition and current rate of progression

you may not notice anything for ages until you (hopefully) realise your

progression has slowed.

Some people with Crohn's only need to take it for a few months till they are

cured and don't need it again.

PS Like anything, it doesn't necessarily work for everyone!

In low dose naltrexone , " emailit2004 "

<emailit2004@...> wrote:

> I would like to know how long it takes before results are seen?

> Do you need to take it a certain number of days before you know if

> its going to work?

>

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Is there really anybody with Crohn's who has been CURED and didn't

need LDN again?

>

> > I would like to know how long it takes before results are seen?

> > Do you need to take it a certain number of days before you know

if

> > its going to work?

> >

>

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,

I can't speak for Skip but from my reading of posts from everybody on

here for over four and a half years I don't believe you can postulate

the converse. I believe all he is saying is that if you do experience

sleep disturbances it is an indication that your body is absorbing the

naltrexone. However, only a relatively small percentage of people have

initial sleep disturbances and LDN still works for many who don't.

JEFFREY ADAMS wrote:

> Skip just posted an interesting comment -- if I understand him

> correctly, if you are getting sleep disturbances, it is highly

> suggestive that you are absorbing LDN and will more likely see

> therapeutic benefit. So, conversely, if you do not experience sleep

> disturbances, this view infers that you are not properly absorbing LDN

> and it is not working for you.

>

> My story is a mixed bag, so not sure what to make of it. I have been

> on LDN for 4 1/2 months for MS (diagnosed 1978). I did not experience

> sleep disturbances, but have had some positive benefits with my vision

> and bladder, and my resting heart rate has decreased (which is a sign

> that my body is under less stress). However, my walking has not seen

> much improvement, since I continue to have significant leg stiffness/

> spasticity, and it is hard to determine if it is a side effect of LDN

> or if it is my baseline spasticity worsening somewhat. I will add

> that, after 30 years with MS the walking is the most difficult part of

> my disease, and I am still able to walk without a cane most of the

> time (albeit with less stability and speed than I'd like thanks to the

> tremendous stiffness).

>

> What would Skip and other experienced readers say about my situation?

> Are there others who have seen therapeutic benefit without the sleep

> disturbances in the beginning? Is there still a possibility that I

> may see some lessening of the spasticity? I have been hearing " wait

> 6-9 months before you conclude that LDN is not helping " , and that the

> leg stiffness will decrease over time.

>

> Clearly, I am hoping for the best, and will hang in there. But Skip's

> comment has made me wonder if I am absorbing LDN as I should be. And

> if I am not, how can I improve absorption?

>

> (I am already on a gluten free, sugar free, " Best Bet " diet, and have

> been for a long time, swim and bike regularly, stretch, etc.)

>

> Thanks in advance!

>

>

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i'll say thisi really liked those sleep disturbances.but I'll say this- i think its important that you keep a short daily diary of how your feelings because many things can be subtle and happen over the span of months. All ldn is suppose to do is stop the progression everything else is gravy.and again having said that if you have ms you aborption issues and if you don't deal with those no you wont get what your are suppose to. and i'll even go a step further to say that the stiffness may more to do with your gut than the ldn and your diet is great you just may need a little more to help everything along.does that make sense?cyndi Cyndi Lenzpsychrn@...clenz@...http://www.tdgr2productions.comwww.skipspharmacy.com On Jun 19, 2008, at 10:26 AM, C wrote:,I can't speak for Skip but from my reading of posts from everybody on here for over four and a half years I don't believe you can postulate the converse. I believe all he is saying is that if you do experience sleep disturbances it is an indication that your body is absorbing the naltrexone. However, only a relatively small percentage of people have initial sleep disturbances and LDN still works for many who don't.JEFFREY ADAMS wrote:> Skip just posted an interesting comment -- if I understand him > correctly, if you are getting sleep disturbances, it is highly > suggestive that you are absorbing LDN and will more likely see > therapeutic benefit. So, conversely, if you do not experience sleep > disturbances, this view infers that you are not properly absorbing LDN > and it is not working for you. > > My story is a mixed bag, so not sure what to make of it. I have been > on LDN for 4 1/2 months for MS (diagnosed 1978). I did not experience > sleep disturbances, but have had some positive benefits with my vision > and bladder, and my resting heart rate has decreased (which is a sign > that my body is under less stress). However, my walking has not seen > much improvement, since I continue to have significant leg stiffness/ > spasticity, and it is hard to determine if it is a side effect of LDN > or if it is my baseline spasticity worsening somewhat. I will add > that, after 30 years with MS the walking is the most difficult part of > my disease, and I am still able to walk without a cane most of the > time (albeit with less stability and speed than I'd like thanks to the > tremendous stiffness). > > What would Skip and other experienced readers say about my situation? > Are there others who have seen therapeutic benefit without the sleep > disturbances in the beginning? Is there still a possibility that I > may see some lessening of the spasticity? I have been hearing "wait > 6-9 months before you conclude that LDN is not helping", and that the > leg stiffness will decrease over time. > > Clearly, I am hoping for the best, and will hang in there. But Skip's > comment has made me wonder if I am absorbing LDN as I should be. And > if I am not, how can I improve absorption? > > (I am already on a gluten free, sugar free, "Best Bet" diet, and have > been for a long time, swim and bike regularly, stretch, etc.)> > Thanks in advance! > >

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I was one who managed to get out of a mobility scooter but it was not

LDN alone that did that. I took advantage of LDN halting my chronic

progressive MS disease progression and went to the YMCA pool 6 days a

week and did no less than 2 hours of my own made up strengthening

water execises for 1 solid year. I then backed off to 3 days a week.

That was 5 years ago and I'm still ambulatory, with pain and

spasticity but if I want to walk on my own then I learn to put up with

that. I am limited in how long I can stand and walk so planning ahead

of time for an outting without mobility assistance is a must.

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CRYSTAL - keep those positive, miracle-type testimonies coming!!! these are the kinds of "injections" we need!!!! we can print these out and take then to our doctors!!

marshiris@...

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I think those that have the worst of the sleep disturbances are those

that make the least endorphins on their own. I know if I miss a couple

doses, I am right back to the original sleep problems when I again

re-start LDN.

Also, I started walking 3 days ago, getting mild cardio effects.

Previously, I had went to a gym for 4 months, at least 4 times a week,

for 2 hours at a time. It felt good to work out, but it was a mental

relief, never a physical one. Now that I started walking again, I

feel, for the first time, the " runner's high " people speak of. The

overall GREAT physical feeling one gets as your heartrate increases. I

have NEVER felt this before when exercising. Again, this lends to my

belief my body was seriously lacking endorphins for years.

Saundra

> > Skip just posted an interesting comment -- if I understand him

> > correctly, if you are getting sleep disturbances, it is highly

> > suggestive that you are absorbing LDN and will more likely see

> > therapeutic benefit. So, conversely, if you do not experience sleep

> > disturbances, this view infers that you are not properly absorbing

LDN

> > and it is not working for you.

> >

> > My story is a mixed bag, so not sure what to make of it. I have been

> > on LDN for 4 1/2 months for MS (diagnosed 1978). I did not

experience

> > sleep disturbances, but have had some positive benefits with my

vision

> > and bladder, and my resting heart rate has decreased (which is a sign

> > that my body is under less stress). However, my walking has not seen

> > much improvement, since I continue to have significant leg stiffness/

> > spasticity, and it is hard to determine if it is a side effect of LDN

> > or if it is my baseline spasticity worsening somewhat. I will add

> > that, after 30 years with MS the walking is the most difficult

part of

> > my disease, and I am still able to walk without a cane most of the

> > time (albeit with less stability and speed than I'd like thanks to

the

> > tremendous stiffness).

> >

> > What would Skip and other experienced readers say about my

situation?

> > Are there others who have seen therapeutic benefit without the sleep

> > disturbances in the beginning? Is there still a possibility that I

> > may see some lessening of the spasticity? I have been hearing " wait

> > 6-9 months before you conclude that LDN is not helping " , and that the

> > leg stiffness will decrease over time.

> >

> > Clearly, I am hoping for the best, and will hang in there. But

Skip's

> > comment has made me wonder if I am absorbing LDN as I should be. And

> > if I am not, how can I improve absorption?

> >

> > (I am already on a gluten free, sugar free, " Best Bet " diet, and have

> > been for a long time, swim and bike regularly, stretch, etc.)

> >

> > Thanks in advance!

> >

> >

>

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Apologies - seems my memory is playing tricks on me. I am 99.99%

confident I have seen posts from at least one person stating that they

were clear of Crohn's symptoms after a few months and were able to stop

taking LDN with no return of symptoms (though given the minute cost and

other benefits of LDN why would you bother stopping it?). I did a

quick(ish) search and couldn't find any messages saying specifically

that (although I still think they're out there!) but did find message

#23071 in which someone reported the following after a phone conference

with Dr Bihari.

" Crohns disease--LDN has dramatically affected 2 dozen cases--all have

responded within 2-3 weeks with a complete clearing of Crohns symptoms

with no return as long as they stay on LDN. Some have been stable for

as long as 5-6 years. "

rachelraneri wrote:

> Is there really anybody with Crohn's who has been CURED and didn't

> need LDN again?

>

>

>

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I was diagnosed with SPMS and Transverse Myelitis November 2004 and the first 8 months used Betaseron and in those first 8 months I went from using a walker, wheelchair to a Hoveround power chair then I started taking LDN September 3rd, 2005 and now I don't have to use anything to help me walk or get around. I walk around without having to use anything. I have been on LDN now for 2 yrs and 9 months.

Hugs & Blessings,

Crystal

LDN_Users Group Owner

Diagnosed November 2004 with Secondary Progressive MS, Transverse Myelitis and an Advocate for LDN!! 2 years & 9 months on LDN with Skip's Pharmacy.....

Crystal's MS,TM & LDN Website

Crystal's LDN Gift Shop

Crystal's LDN Support Group

Skip's Compounding Pharmacy

LDN Website

[low dose naltrexone] Re: how long does ldn take to work?>- You may not experience "results" except no progression or, slowing> down of symptoms. I have not seen or heard of anyone getting out of> a wheelchair but, I guess it can happen. I'm happy with the> stopping, slowing down of MS. Have you read the LDN website? It> would answer most of your questions. >>>>> -- In low dose naltrexone , "Art" <rtee54@...> wrote:>>>> I guess it depends what you're taking it for. Seems those with> Crohn's>> Disease see positive results fairly quickly. I have MS and am> happy>> disease progression has slowed/halted. Not everyone's experiences>> symptom relief, this is considered a bonus.>>>> Art>> -->>>> >> >>> > I would like to know how long it takes before results are seen?>> > Do you need to take it a certain number of days before you know> if>>

> its going to work?>> >>>>>>> ------------------------------------>>

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Hello Crystals. LDN WORKS for you!!! Very good!!!

I have MS too and I have the same problems like you had ( difficult to walk- stifness and spastisity of my legs). I take ldn just in 1.5 weeks.I take 4.5 but i strated to have switching in my legs. From tomorrow I will start to take 3.0mg.How many mg do you take 4.5 or 3.0 mg?

Thank you,

Svetlana>>>> I guess it depends what you're taking it for. Seems those with> Crohn's>> Disease see positive results fairly quickly. I have MS and am> happy>> disease progression has slowed/halted. Not everyone's experiences>> symptom relief, this is considered a bonus.>>>> Art>> -->>>> >> >>> > I would like to know how long it takes before results are seen?>> > Do you need to take it a certain number of days before you know> if>> > its going to work?>> >>>>>>> ------------ ---------

--------- ------>>

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Thanks to the group for comments regarding sleep disturbances, LDN absorption, etc.

To clarify, I am on copaxone injections daily (for about 10 years), take 10 mg. of baclofen 4 times a day for stiffness (should take more but it makes me too drowsy), started LDN at 1.5 mg, moved after a week to 3.0 mg, then moved up again to 4.5 mg after a week. Leg cramping started so I moved back to 3.0 mg for 1 1/12 months, and then thought I should try 4.5 mg again (since it is recognized as the optimal dose for most people) so have been there with out side effects for about 1 1/2 months. I'm getting mixed signals regarding whether I should have stayed at 3.0 mg or not given my spasticity -- I know the website recommends 3.0 but others have encouraged my to up the dose to 4.5 mg.

I am a small person at 5"3" and 110 pounds, but I hear from many that the best adult dose is 4.5 mg, regardless of size. There are a few reporting differently, so who knows.

The leg stiffness seems a little worse since beginning LDN -- but other symptoms are better so all in feel like LDN is working for me. I'd LOVE to reduce the spasticity, as that would make my life so much easier, and will try some of the suggestions offered by Art (I do take a calsium/ magnesium supplement but should try ALA). Like Art, I have years of disease (30 years since diagnosis) so there is only so much I can expect! Just halting the disease would be wonderful.

Thanks again, group!

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JEFFEREY ADAMS - i don't get the idea that the converse of what dr. skip said is a fact!! i think he's just trying to get across that WHATEVER is showing up as a change when you start using LDN - we can assume that it is having SOME KIND of effect on our bodies!! some of us show NONE at all; but find that LDN was working all along, when we get tests run!!

marshiris@...

crohn's disease - 17 years

LDN - 1 YEARGas prices getting you down? Search AOL Autos for fuel-efficient used cars.

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I had sleep disturbances the first 4 months on LDN. On the other hand; this could as well come from the disease itself. Since I have Crohns disease I will have a lack of B 12 amongst other vitamines / minerals, - which often leads to tiredness. So I am not sure if LDN is to blame.

A friend of mine did not get sleep disturbances, but LDN helped her getting rid of her disease activity from the first day (as it did for me), she had a terrible and constant headache due to inflammation in veins of the head (arteritis temporalis), and she has been pain free since she started using LDN. She also got increased energy level as well. Ingrid

[low dose naltrexone] Re: how long does ldn take to work?

Skip just posted an interesting comment -- if I understand him correctly, if you are getting sleep disturbances, it is highly suggestive that you are absorbing LDN and will more likely see therapeutic benefit. So, conversely, if you do not experience sleep disturbances, this view infers that you are not properly absorbing LDN and it is not working for you.

My story is a mixed bag, so not sure what to make of it. I have been on LDN for 4 1/2 months for MS (diagnosed 1978). I did not experience sleep disturbances, but have had some positive benefits with my vision and bladder, and my resting heart rate has decreased (which is a sign that my body is under less stress). However, my walking has not seen much improvement, since I continue to have significant leg stiffness/ spasticity, and it is hard to determine if it is a side effect of LDN or if it is my baseline spasticity worsening somewhat. I will add that, after 30 years with MS the walking is the most difficult part of my disease, and I am still able to walk without a cane most of the time (albeit with less stability and speed than I'd like thanks to the tremendous stiffness).

What would Skip and other experienced readers say about my situation? Are there others who have seen therapeutic benefit without the sleep disturbances in the beginning? Is there still a possibility that I may see some lessening of the spasticity? I have been hearing "wait 6-9 months before you conclude that LDN is not helping", and that the leg stiffness will decrease over time.

Clearly, I am hoping for the best, and will hang in there. But Skip's comment has made me wonder if I am absorbing LDN as I should be. And if I am not, how can I improve absorption?

(I am already on a gluten free, sugar free, "Best Bet" diet, and have been for a long time, swim and bike regularly, stretch, etc.)

Thanks in advance!

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Hello,

What doses of LDN do you take?

Thank you,

Svetlana

From: Gunn Dybfest <gunn.ingrid@...>Subject: Re: [low dose naltrexone] Re: how long does ldn take to work?low dose naltrexone Date: Monday, June 23, 2008, 2:08 PM

I had sleep disturbances the first 4 months on LDN. On the other hand; this could as well come from the disease itself. Since I have Crohns disease I will have a lack of B 12 amongst other vitamines / minerals, - which often leads to tiredness. So I am not sure if LDN is to blame.

A friend of mine did not get sleep disturbances, but LDN helped her getting rid of her disease activity from the first day (as it did for me), she had a terrible and constant headache due to inflammation in veins of the head (arteritis temporalis), and she has been pain free since she started using LDN. She also got increased energy level as well. Ingrid

[low dose naltrexone] Re: how long does ldn take to work?

Skip just posted an interesting comment -- if I understand him correctly, if you are getting sleep disturbances, it is highly suggestive that you are absorbing LDN and will more likely see therapeutic benefit. So, conversely, if you do not experience sleep disturbances, this view infers that you are not properly absorbing LDN and it is not working for you.

My story is a mixed bag, so not sure what to make of it. I have been on LDN for 4 1/2 months for MS (diagnosed 1978). I did not experience sleep disturbances, but have had some positive benefits with my vision and bladder, and my resting heart rate has decreased (which is a sign that my body is under less stress). However, my walking has not seen much improvement, since I continue to have significant leg stiffness/ spasticity, and it is hard to determine if it is a side effect of LDN or if it is my baseline spasticity worsening somewhat. I will add that, after 30 years with MS the walking is the most difficult part of my disease, and I am still able to walk without a cane most of the time (albeit with less stability and speed than I'd like thanks to the tremendous stiffness).

What would Skip and other experienced readers say about my situation? Are there others who have seen therapeutic benefit without the sleep disturbances in the beginning? Is there still a possibility that I may see some lessening of the spasticity? I have been hearing "wait 6-9 months before you conclude that LDN is not helping", and that the leg stiffness will decrease over time.

Clearly, I am hoping for the best, and will hang in there. But Skip's comment has made me wonder if I am absorbing LDN as I should be. And if I am not, how can I improve absorption?

(I am already on a gluten free, sugar free, "Best Bet" diet, and have been for a long time, swim and bike regularly, stretch, etc.)

Thanks in advance!

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Yes, as long as they continue to stay on LDN, though! :-)

Ingrid

Re: [low dose naltrexone] Re: how long does ldn take to work?Apologies - seems my memory is playing tricks on me. I am 99.99% confident I have seen posts from at least one person stating that they were clear of Crohn's symptoms after a few months and were able to stop taking LDN with no return of symptoms (though given the minute cost and other benefits of LDN why would you bother stopping it?). I did a quick(ish) search and couldn't find any messages saying specifically that (although I still think they're out there!) but did find message #23071 in which someone reported the following after a phone conference with Dr Bihari. "Crohns disease--LDN has

dramatically affected 2 dozen cases--all have responded within 2-3 weeks with a complete clearing of Crohns symptoms with no return as long as they stay on LDN. Some have been stable for as long as 5-6 years."rachelraneri wrote:> Is there really anybody with Crohn's who has been CURED and didn't > need LDN again?> >> ------------------------------------

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Valerian works very well.

Art

--

>

> Hello,

> I started on LDN  last Friday , although it took me about six

months to get someone to prescribe it for me. My intern finally did ,

since I have got to try to get off the Prednisone being on it for

such a long time. I have Crohn's and have went all the way to

Washington University to obstain LDN but was turned down there also.

So I was in shock when my own doctor who considers me a hard head

agreed to give me a 5mg dose of Naltrexone.

> I have been reading about this from new releases the last 6

months and only found this group this last weekend. 

> My results have been fantastic.  I have dropped down the Prednisone

several mil. and have been sleeping good. Lots of energy, even took

a  1/2 mile hike this last weekend. The pain has lessened and I have

stopped  my anti depressants.

> I am seeing immediate results and feel like I will get alot

better. I have been on Humira, Immuran, Cipro, Flagyl, Pentasa and

others. I have been hospitalized 4 times in the last year and a half.

I have had breast cancer and had a bileral massectomy also.Nothing

has worked for the Crohns since my stress levels have remained high..

I have been adament with my doctors that I didn't want to suppress my

immune system but boost it so I was immediately interested in LDN.

Seems like I have found the drug for me.  Hope this gives others

encouragement to try. I realize that not everyone will have the same

results.  Hope is so important when you are facing a really difficult

illness. Thanks for all your help, Becky

> P.S Since I am an herbalist, if I do have problems with sleep, I

will try the valerian which I have good results with and the MSM for

any hair loss.

>  

>

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Hi Becky,

this is terrific! The same thing happened to me, too, I felt better the first day after starting LDN. I have been trying to adjust my dosage a bit the last 4 months due to a flare I had in february, I used 4.5 mg, I increased it in february up to 6.0 mg, and I have now used 4.5 mg for some weeks. This was not enough for me, I got pain and something that told me that a flare could return, this made me increase my dose to 5.0 mg. Now I am much better. Still not sure if 6.0 mg could be the best dosage for me, have to use some weeks on each to be sure.

Don't reduce your prednisone too fast. Take your time, do it slow and you will get a payback. I understand why it could be fine to close the relationship with prednisone, it's not a harmless med, but try to taper off of it by using long time. Just to avoid a flare before LDN works 100 %. Good luck.

Ingrid

[low dose naltrexone] Re: how long does ldn take to work?

Skip just posted an interesting comment -- if I understand him correctly, if you are getting sleep disturbances, it is highly suggestive that you are absorbing LDN and will more likely see therapeutic benefit. So, conversely, if you do not experience sleep disturbances, this view infers that you are not properly absorbing LDN and it is not working for you.

My story is a mixed bag, so not sure what to make of it. I have been on LDN for 4 1/2 months for MS (diagnosed 1978). I did not experience sleep disturbances, but have had some positive benefits with my vision and bladder, and my resting heart rate has decreased (which is a sign that my body is under less stress). However, my walking has not seen much improvement, since I continue to have significant leg stiffness/ spasticity, and it is hard to determine if it is a side effect of LDN or if it is my baseline spasticity worsening somewhat. I will add that, after 30 years with MS the walking is the most difficult part of my disease, and I am still able to walk without a cane most of the time (albeit with less stability and speed than I'd like thanks to the tremendous stiffness).

What would Skip and other experienced readers say about my situation? Are there others who have seen therapeutic benefit without the sleep disturbances in the beginning? Is there still a possibility that I may see some lessening of the spasticity? I have been hearing "wait 6-9 months before you conclude that LDN is not helping", and that the leg stiffness will decrease over time.

Clearly, I am hoping for the best, and will hang in there. But Skip's comment has made me wonder if I am absorbing LDN as I should be. And if I am not, how can I improve absorption?

(I am already on a gluten free, sugar free, "Best Bet" diet, and have been for a long time, swim and bike regularly, stretch, etc.)

Thanks in advance!

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