Question about low evening endorphins... dosage question.

[Guest guest]

Hello. I have a dosage question for my son, 14, with Crohn's. I spoke

to Dr. Skip the other day and he probably told me the answer, but that

was before this issue came up and now I'm not sure what to do. Dr. Skip

or anyone, please advise. My son is taking 2 mg LDN and coming off of a

really bad Crohn's flare due to allergies. He is taking 20mg

Prednisone and tapering. It was not an option to wait for 10mg dosage

of steriods, and we do not think that is the issue. He's doing very

well on LDN, has a huge appetite and feels really good all day. He has

gotten up at around 4am the last 2-3 mornings to have something to

eat.. maybe because his body is pushing to catch up nutrition now that

he's feeling better (this would not be unusual), or maybe because of

LDN.?? Then he sleeps a while longer and wakes up full of pleasant

conversation and wants breakfast. However, in the evenings, he's cranky

and irritable, kind of seeming tired and distressed like there's some

kind of struggle- it's not a behavorial issue, but something to do with

his body chemistry. Does this sound like low endorphins? I wonder if

this means his evening endorphins are too low and what that means for

LDN dosage.. should we increase or decrease?

[Guest guest]

to keep the endorphines working longer,you should consider taking DL-

phenylalanine

>

> Hello. I have a dosage question for my son, 14, with Crohn's. I

spoke

> to Dr. Skip the other day and he probably told me the answer, but

that

> was before this issue came up and now I'm not sure what to do. Dr.

Skip

> or anyone, please advise. My son is taking 2 mg LDN and coming off

of a

> really bad Crohn's flare due to allergies. He is taking 20mg

> Prednisone and tapering. It was not an option to wait for 10mg

dosage

> of steriods, and we do not think that is the issue. He's doing

very

> well on LDN, has a huge appetite and feels really good all day. He

has

> gotten up at around 4am the last 2-3 mornings to have something to

> eat.. maybe because his body is pushing to catch up nutrition now

that

> he's feeling better (this would not be unusual), or maybe because

of

> LDN.?? Then he sleeps a while longer and wakes up full of pleasant

> conversation and wants breakfast. However, in the evenings, he's

cranky

> and irritable, kind of seeming tired and distressed like there's

some

> kind of struggle- it's not a behavorial issue, but something to do

with

> his body chemistry. Does this sound like low endorphins? I wonder

if

> this means his evening endorphins are too low and what that means

for

> LDN dosage.. should we increase or decrease?

>

[Guest guest]

Hello Sherrie,

We have been through similar scenarios. If I have to look for reasons behind your observations, based on our experience, the improved appetite could be attributed to 20Mg of prednisone. Prednisone is also well-known to cause crankiness. You are doing a good thing in getting on with LDN before Prednisone is tapered further. LDN should facilitate the tapering of prednisone, as we experienced. Also, we had better results increasing the LDN from 3.5 to 4.5mg. But the same dosage may not hold good for everyone. So in your case, trying 4mg for a few days instead of 2mg is possibly a good idea. I am sure you would be able to tell in a few days if it is helping or not.

Good luck.

-----Original Message-----From: low dose naltrexone [mailto:low dose naltrexone ]On Behalf Of sherrywphippsSent: Thursday, June 05, 2008 11:11 PMlow dose naltrexone Subject: [low dose naltrexone] Question about low evening endorphins... dosage question.

Hello. I have a dosage question for my son, 14, with Crohn's. I spoke to Dr. Skip the other day and he probably told me the answer, but that was before this issue came up and now I'm not sure what to do. Dr. Skip or anyone, please advise. My son is taking 2 mg LDN and coming off of a really bad Crohn's flare due to allergies. He is taking 20mg Prednisone and tapering. It was not an option to wait for 10mg dosage of steriods, and we do not think that is the issue. He's doing very well on LDN, has a huge appetite and feels really good all day. He has gotten up at around 4am the last 2-3 mornings to have something to eat.. maybe because his body is pushing to catch up nutrition now that he's feeling better (this would not be unusual), or maybe because of LDN.?? Then he sleeps a while longer and wakes up full of pleasant conversation and wants breakfast. However, in the evenings, he's cranky and irritable, kind of seeming tired and distressed like there's some kind of struggle- it's not a behavorial issue, but something to do with his body chemistry. Does this sound like low endorphins? I wonder if this means his evening endorphins are too low and what that means for LDN dosage.. should we increase or decrease?

[Guest guest]

>

> Hello Sherrie,

>

> We have been through similar scenarios. If I have to look for

reasons behind

> your observations, based on our experience, the improved appetite

could be

> attributed to 20Mg of prednisone. Prednisone is also well-known to

cause

> crankiness. You are doing a good thing in getting on with LDN before

> Prednisone is tapered further. LDN should facilitate the tapering of

> prednisone, as we experienced. Also, we had better results

increasing the

> LDN from 3.5 to 4.5mg. But the same dosage may not hold good for

everyone.

> So in your case, trying 4mg for a few days instead of 2mg is

possibly a good

> idea. I am sure you would be able to tell in a few days if it is

helping or

> not.

>

> Good luck.

>

> [low dose naltrexone] Question about low evening

endorphins...

> dosage question.

>

>

> Hello. I have a dosage question for my son, 14, with Crohn's. I

spoke

> to Dr. Skip the other day and he probably told me the answer, but

that

> was before this issue came up and now I'm not sure what to do.

Dr. Skip

> or anyone, please advise. My son is taking 2 mg LDN and coming

off of a

> really bad Crohn's flare due to allergies. He is taking 20mg

> Prednisone and tapering. It was not an option to wait for 10mg

dosage

> of steriods, and we do not think that is the issue. He's doing

very

> well on LDN, has a huge appetite and feels really good all day.

He has

> gotten up at around 4am the last 2-3 mornings to have something to

> eat.. maybe because his body is pushing to catch up nutrition now

that

> he's feeling better (this would not be unusual), or maybe because

of

> LDN.?? Then he sleeps a while longer and wakes up full of pleasant

> conversation and wants breakfast. However, in the evenings, he's

cranky

> and irritable, kind of seeming tired and distressed like there's

some

> kind of struggle- it's not a behavorial issue, but something to

do with

> his body chemistry. Does this sound like low endorphins? I wonder

if

> this means his evening endorphins are too low and what that means

for

> LDN dosage.. should we increase or decrease?

>

DLPA is a very cheap amino acid (order it from puritans pride)--it

helps by protecting the endorphins from being broken down too fast.

also supposed to help with pain and energy.