Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 Since I started my son on the inositol, it seems that he is a bit crabbier lately. It could also be because the routine has changed due to school being out, but I wondered if anyone else has experienced this. I started him very slowly--only 1/4 capsule (total capsule mg is 500). thanks! Laurie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 Some people don't react well to inositol. Andy has said it can be from temporal lobe problems.. Amen (the SPECT brain scan authority) says temporal lobes are very easily damaged by shocks to the head, even ones unaccompanied by loss of consciousness, e.g. hitting a soccor ball with the head. Personally, inositol makes my head feel clogged up (not sure if its anything to do with my temporal lobes, though I did have a head injury a few years ago). See here for Andy's posts on inositol and temporal lobe(s): http://onibasu.com/cgi-bin/search.cgi?query=inositol+lobe*+%2Bfrom%3Aandycutler & \ submit=Search%21 & max=20 & sort=score & idxname=am Jay > > Since I started my son on the inositol, it seems that he is a bit > crabbier lately. It could also be because the routine has changed due > to school being out, but I wondered if anyone else has experienced > this. I started him very slowly--only 1/4 capsule (total capsule mg is > 500). thanks! > > Laurie > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 Being that you've noted a poor response to inositol, and I do as well, you might consider trying nutrients that Willam Walsh has found of utility for overmethylated subjects as his experience has been that while undermethylators do well with it, overmethylators often respond poorly. The nutrients typically helpful in cases of overmethylation include folic acid, choline, DMAE, and copper. Of course, copper supplementaion should be questioned in mercury toxic individuals. > > > > Since I started my son on the inositol, it seems that he is a bit > > crabbier lately. It could also be because the routine has changed due > > to school being out, but I wondered if anyone else has experienced > > this. I started him very slowly--only 1/4 capsule (total capsule mg is > > 500). thanks! > > > > Laurie > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 It could also be just an intolerance. FWIW my son is very much an undermethylator, yet does poorly on inositol. He gets unhappy, spacey, a little stimmy, and then he starts getting loose stools. He exhibits his usual IgG reaction to inositol, basically. As soon as we stopped it everything cleared up and he went back to " normal. " On the other hand I do fantastic on inositol! It helps my PCOS, and magically lowered my cholesterol 30 points in the span of 2 months of high daily dosing (5 g). Wow! > > > > > > Since I started my son on the inositol, it seems that he is a bit > > > crabbier lately. It could also be because the routine has > changed due > > > to school being out, but I wondered if anyone else has > experienced > > > this. I started him very slowly--only 1/4 capsule (total capsule > mg is > > > 500). thanks! > > > > > > Laurie > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 Very good point! I, too, exibit more traits of under than overmethylation, despite my consistently poor response to inositol. Though, since W.Walsh has noted this pattern, and he's had the opportunity to observe impressive numbers of individuals, a trial with one or more overmethylation supportive nutrients is rational. It makes me happy to hear of your excellent response to inositol supplementation. Best regards, > > > > > > > > Since I started my son on the inositol, it seems that he is a bit > > > > crabbier lately. It could also be because the routine has > > changed due > > > > to school being out, but I wondered if anyone else has > > experienced > > > > this. I started him very slowly--only 1/4 capsule (total capsule > > mg is > > > > 500). thanks! > > > > > > > > Laurie > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 I am having a hard time deciding if my son is an over or undermethylator. He has almost all of the symptoms of an under methylator (seasonal allergies,strong will, ocd, slenderness), yet according to bloodwork ('05), his histadine levels were normal. Now in the urine, they were really low--does that make any sense? Also, in the urine, the 1-methylhistadine and the 3-methylhistadine were also low. He does very well with melatonin to help him sleep at night. I think that is related somehow. Anyone that can help, I would greatly appreciate it. I am afraid to try the TMG that I bought. thanks, Laurie > > > > I have to say that I did awful on inositol, but have fared FANTASTICALLY on > L-Tryptophan. It got a bad rap, due to a bad manufacturer a while ago, but > it seems safe enough for me now (Source Naturals brand). I have struggled > with anxiety and mood disorders for my whole life and this L- tryptophan along > with niacinamide and B6 has done wonders. > > HTH > > In a message dated 6/14/2008 6:30:53 P.M. Eastern Daylight Time, > pegapud@... writes: > > It could also be just an intolerance. FWIW my son is very much an > undermethylator, yet does poorly on inositol. He gets unhappy, > spacey, a little stimmy, and then he starts getting loose stools. He > exhibits his usual IgG reaction to inositol, basically. As soon as we > stopped it everything cleared up and he went back to " normal. " On the > other hand I do fantastic on inositol! It helps my PCOS, and > magically lowered my cholesterol 30 points in the span of 2 months of > high daily dosing (5 g). Wow! > > > > > > > > Robyn Gillis > > Support Autism Research > _www.ronanjames.etsy.com_ (http://www.ronanjames.etsy.com/) > > _www.ronanjames.wordpress.com_ (http://www.ronanjames.wordpress.com/) > > > > > **************Vote for your city's best dining and nightlife. City's Best > 2008. (http://citysbest.aol.com?ncid=aolacg00050000000102) > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 > > > > > > Since I started my son on the inositol, it seems that he is a bit > > > crabbier lately. It could also be because the routine has > changed due > > > to school being out, but I wondered if anyone else has > experienced > > > this. I started him very slowly--only 1/4 capsule (total capsule > mg is > > > 500). thanks! > > > > > > Laurie > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2008 Report Share Posted June 14, 2008 I can sympathize with your situation. While histamine production is influenced by histidine levels, we cannot actually know if someone is high, low, or normal in the histamine department based on histidine levels (or that of it's methylated derivatives). The symptoms that you've noted in your son justify an ABAB trial utilizing TMG. Don't be afraid in your efforts to heal him. I would administer it along the lines of 3-7 days on, 3-7 days off, followed by another 3-7 days on and 3-7 days off - whichever number of days you decide upon, the number of on/off days should be held consistent. By, or before, the end of the trial, given that the dosage is adeqaute, you will see a pattern. You will then know that much more about your son's metabolism and his needs, including if TMG therapy is appropriate. Good luck, > > > > > > > > I have to say that I did awful on inositol, but have fared > FANTASTICALLY on > > L-Tryptophan. It got a bad rap, due to a bad manufacturer a while > ago, but > > it seems safe enough for me now (Source Naturals brand). I have > struggled > > with anxiety and mood disorders for my whole life and this L- > tryptophan along > > with niacinamide and B6 has done wonders. > > > > HTH > > > > In a message dated 6/14/2008 6:30:53 P.M. Eastern Daylight Time, > > pegapud@ writes: > > > > It could also be just an intolerance. FWIW my son is very much an > > undermethylator, yet does poorly on inositol. He gets unhappy, > > spacey, a little stimmy, and then he starts getting loose stools. > He > > exhibits his usual IgG reaction to inositol, basically. As soon as > we > > stopped it everything cleared up and he went back to " normal. " On > the > > other hand I do fantastic on inositol! It helps my PCOS, and > > magically lowered my cholesterol 30 points in the span of 2 months > of > > high daily dosing (5 g). Wow! > > > > > > > > > > > > > > > > Robyn Gillis > > > > Support Autism Research > > _www.ronanjames.etsy.com_ (http://www.ronanjames.etsy.com/) > > > > _www.ronanjames.wordpress.com_ > (http://www.ronanjames.wordpress.com/) > > > > > > > > > > **************Vote for your city's best dining and nightlife. > City's Best > > 2008. (http://citysbest.aol.com?ncid=aolacg00050000000102) > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 15, 2008 Report Share Posted June 15, 2008 Thank you and others for your responses. My son resonded well to a trial of Benadryl a few years ago during the spring allergy season. That led me to believe that he had too much histamine. At the time, his behavior improved while on the Benadryl. We really haven't had to use it since then. I'm not sure what that means. I did purchase some TMG, so I willtry that. I am going to give the inositol a couple more days before I give up. His language seems to have improved a bit since starting it. The crabbiness seems better today. Laurie > > > > I am having a hard time deciding if my son is an over or > > undermethylator. He has almost all of the symptoms of an under > > methylator (seasonal allergies,strong will, ocd, slenderness), yet > > according to bloodwork ('05), his histadine levels were normal. > Now > > in the urine, they were really low--does that make any sense? > Also, > > in the urine, the 1-methylhistadine and the 3-methylhistadine were > > also low. He does very well with melatonin to help him sleep at > > night. I think that is related somehow. Anyone that can help, I > > would greatly appreciate it. I am afraid to try the TMG that I > > bought. > > thanks, > > Laurie > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 15, 2008 Report Share Posted June 15, 2008 Andy, I hold all that you share in the highest of esteem, but I wonder how Walsh came to the conclusion that copper is sometimes valuable (in mercury toxics). Have you discussed this with him? Your insight is always appreciated. Laurie, improved language is tough to ignore. If you are considering giving up on inositol, you might consider ABABing it instead. When you go on, then off, then on again and off again, you make it difficult for confounding variables to blurr your observations. It should go without saying that everything, other than the compound being experimented with, should remain as unchanged as possible (e.g., other supplements/meds, routines, etc.) Good luck, > > > > > > > > > > Since I started my son on the inositol, it seems that he is a bit > > > > > crabbier lately. It could also be because the routine has > > > changed due > > > > > to school being out, but I wondered if anyone else has > > > experienced > > > > > this. I started him very slowly--only 1/4 capsule (total capsule > > > mg is > > > > > 500). thanks! > > > > > > > > > > Laurie > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > ======================================================= > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 17, 2008 Report Share Posted June 17, 2008 , I decided to keep him on the inositol and ride it out. He has gotten better with the crabbiness also. Thanks! > > > > > > > > > > > > Since I started my son on the inositol, it seems that he is > a bit > > > > > > crabbier lately. It could also be because the routine has > > > > changed due > > > > > > to school being out, but I wondered if anyone else has > > > > experienced > > > > > > this. I started him very slowly--only 1/4 capsule (total > capsule > > > > mg is > > > > > > 500). thanks! > > > > > > > > > > > > Laurie > > > > > > > > > > > > > > > > > > > > > > > > > > > ------------------------------------ > > > > > > ======================================================= > > > Quote Link to comment Share on other sites More sharing options...
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