OT - Rx Enbrel reverses Alzheimer's in minutes

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http://www.thisislondon.co.uk/news/article-23431610-details/Drug%20%27can%20reve\

rse%20Alzheimer%27s%20symptoms%20in%20minutes%27/article.do

excerpt...

" A drug used for arthritis can reverse the symptoms of Alzheimer's " in

minutes " .

It appears to tackle one of the main features of the disease - inflammation

in the brain.

The drug, called Enbrel, is injected into the spine where it blocks a

chemical responsible for damaging the brain and other organs.

A pilot study carried out by U.S. researchers found one patient had his

symptoms reversed " in minutes " . "

.......

When used by arthritis sufferers, the drug is self-administered by injection

and researchers had to develop a way of injecting it into the spine to affect

the brain cells.

Sue , a researcher at the University of Arkansas for Medical

Sciences, said: 'It is unprecedented to see cognitive and behavioural

improvement in a

patient with established dementia within minutes of therapeutic intervention.

'This gives all of us in Alzheimer research a tremendous new clue

about new avenues of research.' Enbrel is not approved for treating

Alzheimer's in the U.S. or the UK and is regarded as highly experimental, said

Dr

.

'Even though this report predominantly discusses a single patient it is of

significant scientific interest because of the potential insight it may give

into the processes involved in the brain dysfunction of Alzheimer's,' she added.

Lead author of the study Tobinick, of the University of California

and Director of the Institute for Neurological Research, said the drug had 'a

very rapid effect that's never been reported in a human being

before'.....Alzheimer's Society charity, said: 'The pursuit of a miracle cure

for Alzheimer's

continues to drive research into a variety of potential treatment targets.

These include a possible link between inflammatory reactions in the brain

and Alzheimer's.'

Children exposed to lead in old paint, n pipes and toys could be at

risk of Alzheimer's later in life, scientists said yesterday.

A study shows that even small amounts of the metal in the first few years

can build up plaques around the brain.

Scientists at the University of Rhode Island told the New Scientist that

they fed infant formula milk laced with low doses of lead to baby monkeys, then

followed their progress for 23 years. A post mortem of the brains revealed

plaques - harmful deposits of protein found in Alzheimer's patients.

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