Guest guest Posted July 15, 2008 Report Share Posted July 15, 2008 Ok, I haven't been able to really find exactly what the diurnal cycle is, I will continue to look after my doctor's appointment this morning. What it seems to be is simply when certain hormones, endorphins and such, are produced in regards to " normal " waking and sleeping hours...hours of daylight and hours of darkness. (I could be completely wrong, so please investigate yourself) What I did find is what seems to be many different " types " of diurnal cycles. IT seems cortisol has a diurnal cycle.(normal cortisol levels should be highest upon waking in AM...steadily drop throughout the day, and be lowest at midnight when one should be asleep) IF this is so, it would definitely stand to reason that those of us with autoimmune thyroid disease, may very well function on a different cycle. Since more often than not, one with thyroid disease also suffers from adrenal fatigue,and suboptimal cortisol levels. I have found that many, if not most, of us also have a flipped rhythm..ie..highest levels of cortisol at midnight, lowest upon waking in the morning...exact opposite of how it should be. (possibly because the body finds it easiest to produce the lacking hormones, and cortisol while the body is at rest) I would think this would affect other cycles within the body as well. There is a pituitary/thyroid/adrenal axis. They all work in conjuction of one another. In my experience, most doctors don't think this axis is important in treating thyroid function. I do understand Cortisol is a touchy hormone, that fluctuates throughout the day. Tests aren't as accurate as doctors' would like. However, if the Cortisol rhythm is flipped (as mine is) it would stand to reason that the whole sleep/wake cycle is off. (definitely is in my case) As are other diurnal cycles...the body must work in harmony...like a finely tuned machine...a zero tolerance motor if you will...well, maybe not quite that exact...lol)and possibly this diurnal cycle may vary from subject to subject. Quite possibly why some with thyroid/adrenal issues have found success in daytime LDN dosing....or at least more success than one with a normal body rhythm might find with daytime dosing. Just me thinking out loud....I could be completely off here. Anybody knowledgeable on this?? Saundra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2008 Report Share Posted July 15, 2008 what was the original question...those on a different circadian clock may obtain the same benefits taking ldn in the a.m.? i have a good book at home about circadian rhythms, it does talk about when in the rhythm that all hormones are produced, i do not recall it mentioning endorphins, but it might discuss them. i have numerous sleep disorders which all might be caused by my circadian disorder called delayed sleep phase syndrome, so i have numerous books about sleep and hormones, one hormone book i have not read yet, duh, cause i fall asleep all the time, i am surprised i get any reading done. i've been hypothyrod all my life, and yes, when one gland is not functioning properly, the rest in the feedback loop don't either, why, because they all talk to each other thru manufacturing of hormones and stimulating hormones, or the lack of each. good sleep hygiene helps, phototherapy helps...some, for the rest of us, these circadian disorders are persistent and permanent and not only usually worsen themselves, but contribute to causing other medical issues, cancer, diabetes, heart disease being the BIG 3. marg > > Ok, I haven't been able to really find exactly what the diurnal cycle > is, I will continue to look after my doctor's appointment this > morning. What it seems to be is simply when certain hormones, > endorphins and such, are produced in regards to " normal " waking and > sleeping hours...hours of daylight and hours of darkness. (I could be > completely wrong, so please investigate yourself) > What I did find is what seems to be many different " types " of diurnal > cycles. IT seems cortisol has a diurnal cycle.(normal cortisol levels > should be highest upon waking in AM...steadily drop throughout the > day, and be lowest at midnight when one should be asleep) IF this is > so, it would definitely stand to reason that those of us with > autoimmune thyroid disease, may very well function on a different > cycle. Since more often than not, one with thyroid disease also > suffers from adrenal fatigue,and suboptimal cortisol levels. I have > found that many, if not most, of us also have a flipped > rhythm..ie..highest levels of cortisol at midnight, lowest upon waking > in the morning...exact opposite of how it should be. (possibly because > the body finds it easiest to produce the lacking hormones, and > cortisol while the body is at rest) I would think this would affect > other cycles within the body as well. There is a > pituitary/thyroid/adrenal axis. They all work in conjuction of one > another. In my experience, most doctors don't think this axis is > important in treating thyroid function. I do understand Cortisol is a > touchy hormone, that fluctuates throughout the day. Tests aren't as > accurate as doctors' would like. However, if the Cortisol rhythm is > flipped (as mine is) it would stand to reason that the whole > sleep/wake cycle is off. (definitely is in my case) As are other > diurnal cycles...the body must work in harmony...like a finely tuned > machine...a zero tolerance motor if you will...well, maybe not quite > that exact...lol)and possibly this diurnal cycle may vary from subject > to subject. Quite possibly why some with thyroid/adrenal issues have > found success in daytime LDN dosing....or at least more success than > one with a normal body rhythm might find with daytime dosing. > Just me thinking out loud....I could be completely off here. Anybody > knowledgeable on this?? > Saundra > Quote Link to comment Share on other sites More sharing options...
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