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Ok, I haven't been able to really find exactly what the diurnal cycle

is, I will continue to look after my doctor's appointment this

morning. What it seems to be is simply when certain hormones,

endorphins and such, are produced in regards to " normal " waking and

sleeping hours...hours of daylight and hours of darkness. (I could be

completely wrong, so please investigate yourself)

What I did find is what seems to be many different " types " of diurnal

cycles. IT seems cortisol has a diurnal cycle.(normal cortisol levels

should be highest upon waking in AM...steadily drop throughout the

day, and be lowest at midnight when one should be asleep) IF this is

so, it would definitely stand to reason that those of us with

autoimmune thyroid disease, may very well function on a different

cycle. Since more often than not, one with thyroid disease also

suffers from adrenal fatigue,and suboptimal cortisol levels. I have

found that many, if not most, of us also have a flipped

rhythm..ie..highest levels of cortisol at midnight, lowest upon waking

in the morning...exact opposite of how it should be. (possibly because

the body finds it easiest to produce the lacking hormones, and

cortisol while the body is at rest) I would think this would affect

other cycles within the body as well. There is a

pituitary/thyroid/adrenal axis. They all work in conjuction of one

another. In my experience, most doctors don't think this axis is

important in treating thyroid function. I do understand Cortisol is a

touchy hormone, that fluctuates throughout the day. Tests aren't as

accurate as doctors' would like. However, if the Cortisol rhythm is

flipped (as mine is) it would stand to reason that the whole

sleep/wake cycle is off. (definitely is in my case) As are other

diurnal cycles...the body must work in harmony...like a finely tuned

machine...a zero tolerance motor if you will...well, maybe not quite

that exact...lol)and possibly this diurnal cycle may vary from subject

to subject. Quite possibly why some with thyroid/adrenal issues have

found success in daytime LDN dosing....or at least more success than

one with a normal body rhythm might find with daytime dosing.

Just me thinking out loud....I could be completely off here. Anybody

knowledgeable on this??

Saundra

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what was the original question...those on a different circadian clock

may obtain the same benefits taking ldn in the a.m.?

i have a good book at home about circadian rhythms, it does talk

about when in the rhythm that all hormones are produced, i do not

recall it mentioning endorphins, but it might discuss them.

i have numerous sleep disorders which all might be caused by my

circadian disorder called delayed sleep phase syndrome, so i have

numerous books about sleep and hormones, one hormone book i have not

read yet, duh, cause i fall asleep all the time, i am surprised i get

any reading done.

i've been hypothyrod all my life, and yes, when one gland is not

functioning properly, the rest in the feedback loop don't either,

why, because they all talk to each other thru manufacturing of

hormones and stimulating hormones, or the lack of each.

good sleep hygiene helps, phototherapy helps...some, for the rest of

us, these circadian disorders are persistent and permanent and not

only usually worsen themselves, but contribute to causing other

medical issues, cancer, diabetes, heart disease being the BIG 3.

marg

>

> Ok, I haven't been able to really find exactly what the diurnal

cycle

> is, I will continue to look after my doctor's appointment this

> morning. What it seems to be is simply when certain hormones,

> endorphins and such, are produced in regards to " normal " waking and

> sleeping hours...hours of daylight and hours of darkness. (I could

be

> completely wrong, so please investigate yourself)

> What I did find is what seems to be many different " types " of

diurnal

> cycles. IT seems cortisol has a diurnal cycle.(normal cortisol

levels

> should be highest upon waking in AM...steadily drop throughout the

> day, and be lowest at midnight when one should be asleep) IF this is

> so, it would definitely stand to reason that those of us with

> autoimmune thyroid disease, may very well function on a different

> cycle. Since more often than not, one with thyroid disease also

> suffers from adrenal fatigue,and suboptimal cortisol levels. I have

> found that many, if not most, of us also have a flipped

> rhythm..ie..highest levels of cortisol at midnight, lowest upon

waking

> in the morning...exact opposite of how it should be. (possibly

because

> the body finds it easiest to produce the lacking hormones, and

> cortisol while the body is at rest) I would think this would affect

> other cycles within the body as well. There is a

> pituitary/thyroid/adrenal axis. They all work in conjuction of one

> another. In my experience, most doctors don't think this axis is

> important in treating thyroid function. I do understand Cortisol is

a

> touchy hormone, that fluctuates throughout the day. Tests aren't as

> accurate as doctors' would like. However, if the Cortisol rhythm is

> flipped (as mine is) it would stand to reason that the whole

> sleep/wake cycle is off. (definitely is in my case) As are other

> diurnal cycles...the body must work in harmony...like a finely tuned

> machine...a zero tolerance motor if you will...well, maybe not quite

> that exact...lol)and possibly this diurnal cycle may vary from

subject

> to subject. Quite possibly why some with thyroid/adrenal issues have

> found success in daytime LDN dosing....or at least more success than

> one with a normal body rhythm might find with daytime dosing.

> Just me thinking out loud....I could be completely off here.

Anybody

> knowledgeable on this??

> Saundra

>

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