Guest guest Posted September 1, 1999 Report Share Posted September 1, 1999 hello, bleeding gums? Well as a stundent(at Marmara University Faculty of Medicine), I should not do medical recommendations; but If I were an MD I would probably ask for the following tests. tt,pt,ptt,thrombocyte count That's why don't you consult your doc.? (brushing teeths regularly ?) original article:hyperthyroidism/?start=26 92 > Hi Everyone, > Sheri emailed me and asked me if I had any suggestions for her bleeding > gums. She has hyperT and has been taking just about everything on the > supplement list, but her gums continue to bleed. > I had to scratch my head for awhile and finally looked up bleeding gums > in some health books. I'd forgotten that everyone recommends bioflavonoids, > rutin, and quercetin for this condition. > Vitamin C and copper are also beneficial because bleeding gums are a result > of poor collagen, but Sheri has been taking both of these. > A few months ago I had studied the flavonoids and found some intriguing > but inconclusive information. I decided to look into them again and found > some very interesting information. > Flavonoids, as defined in the medical dictionary, are " any of a group of > compounds containing a characteristic aromatic trimeric heterocyclic nucleus, > usually occurring in glycosidic form and widely distributed in plants, often > as a pigment. A subgroup with biological activity in mammals is termed the > bioflavonoids. " Basically they are compounds in plants which usually have a > color and they have biological activity. Some researchers feel that they > have hormone activities. > Several researchers have found that some flavonoids have thyroid > suppressive properties and they specifically inhibit deiodinase, the enzyme > which converts T4 to T3. Quoting one study, " Flavonoids are potent non-toxic > ITH (iodothyronine) deiodinase inhibitors in microsomal membranes, and intact > rat hepatocytes. Flavonoids are specific high affinity competitors for > L-T4-binding to human TBPA, weaker antagonists in the rT3-5'deiodinase > reaction, and very poor inhibitors of T3 binding to the nuclear T3 receptor. > Optimized flavonoid antagonists exhibit an ITH bio-isosteric structure and > conformation. " > One flavonoid has been found which has very strong effects and is termed > EMD21388. In one experiment on rats, " EMD 21388 decreased plasma thyroid > hormone concentrations, but thyrotropin levels (TSH) in plasma and pituitary > did not change. Plasma clearance rates for T4 and T3 increased. Thyroidal T4 > secretion was diminished, but T3 secretion was elevated. Extrathyroidal T3 > production by 5'-deiodination was lower. T4 concentrations were markedly > lower in all tissues investigated. Total tissue T3 was lower in brown adipose > tissue, brain, cerebellum, and pituitary, tissues that express the type II > 5'-deiodinase isozyme due to decreased local T3 production. Most tissues > showed increased tissue/plasma ratios for T4 and T3. These results indicate > that this flavonoid diminished T4 and increased T3 secretion by the thyroid, > probably in analogy with other natural flavonoids, by interference with one > or several steps between iodide uptake, organification, and hormone > synthesis. " > Another study states, " Flavonoids are widely distributed in plant-derived > foods and possess a variety of biological activities including antithyroid > effects in experimental animals and humans. A structure-activity study of 13 > commonly consumed flavonoids was conducted to evaluate inhibition of thyroid > peroxidase (TPO), the enzyme that catalyzes thyroid hormone biosynthesis. > Most flavonoids tested were potent inhibitors of TPO, with IC50 values > ranging from 0.6 to 41 microM. Inhibition by the more potent compounds, > fisetin, kaempferol, naringenin, and quercetin, which contain a resorcinol > moiety, was consistent with mechanism-based inactivation of TPO as previously > observed for resorcinol and derivatives. " > Two other studies showed that the grain, millet, has flavonoids which > have very strong antithyroid effects. The researchers were concerned that > the high consumption of millet in areas of Africa where iodine is very sparse > was a major contributor to goiter in those areas. Analysis of millet showed > that the active compounds may be glycosylflavones. The study states: " At a > concentration of 60 mumol/L, glucosylvitexin, the major C-glycosylflavone > present in millet, had effects comparable to those of 1 mumol/L MMI. " MMI is > methimazole, the antithyroidal we know as Tapazole. > I found this particularly interesting because when I was recovering from > hyperT, I had just switched my breakfast grain from rice to millet. I was > getting progressively sicker eating rice, but once I started eating millet I > began to get better. I also just started taking copper, biotin and other > nutrients that I'm sure were important, so there is no way to tell how > important the millet was in my recovery. Later I switched from millet to > oatmeal and continued to improve. I have taken bioflavonoid supplements and > rutin in the past for short periods, but have taken quercetin for a long time > now. > Flavonoids are important parts of the raw fruits and vegetables that we > eat and would seem to be indispensible parts of our diet. The highly visible > colors that flavonoids impart to foods may be important in attracting the > attention of animals. > Given the fact that flavonoids are important for collagen formation and > seem to be involved in copper metabolism, I think it's important to make sure > that either the diet is rich in raw foods and flavonoids, or bioflavonoids > are supplemented. Now that I'm aware of this connection, I'll pay more > attention to it as I research. If you're hyper, you might want to try millet > for breakfast. You should purchase hulled millet and cook in the ratio of > one cup of millet and FOUR cups of water (that will feed about 4 people). I > eat it with lots of butter, a little salt, and a little honey. Looking back > in my diary I can see that on many days I felt much better by the end of the > day if I had millet for breakfast. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 1, 1999 Report Share Posted September 1, 1999 Bleeding gums may or may not have anything to do with hyperthyroidism. Years ago I noticed whenever my brother came to see me from Florida and brought bushels of fresh oranges that my gums would start bleeding. Whenever I stopped eating them, my gums stopped bleeding. My dentist did not believe me, but later I read in Prevention Magazine that oranges cause some persons gums to bleed. Not long ago, I was not feeling well so I began drinking more fruit and vegetable juices, including orange juice. My gums began bleeding again. Gloria From: dremre1977@... <dremre1977@...> hyperthyroidismegroups <hyperthyroidismegroups> Date: Wednesday, September 01, 1999 9:20 AM Subject: Re: Flavonoids > hello, > bleeding gums? Well as a stundent(at Marmara University Faculty of >Medicine), I should not do medical recommendations; but If I were an >MD I would probably ask for the following tests. > tt,pt,ptt,thrombocyte count > That's why don't you consult your doc.? > (brushing teeths regularly ?) >original article:hyperthyroidism/?start=26 >92 >> Hi Everyone, >> Sheri emailed me and asked me if I had any suggestions for her >bleeding >> gums. She has hyperT and has been taking just about everything on >the >> supplement list, but her gums continue to bleed. >> I had to scratch my head for awhile and finally looked up >bleeding gums >> in some health books. I'd forgotten that everyone recommends >bioflavonoids, >> rutin, and quercetin for this condition. >> Vitamin C and copper are also beneficial because bleeding gums are a >result >> of poor collagen, but Sheri has been taking both of these. >> A few months ago I had studied the flavonoids and found some >intriguing >> but inconclusive information. I decided to look into them again and >found >> some very interesting information. >> Flavonoids, as defined in the medical dictionary, are " any of a >group of >> compounds containing a characteristic aromatic trimeric heterocyclic >nucleus, >> usually occurring in glycosidic form and widely distributed in >plants, often >> as a pigment. A subgroup with biological activity in mammals is >termed the >> bioflavonoids. " Basically they are compounds in plants which usually >have a >> color and they have biological activity. Some researchers feel that >they >> have hormone activities. >> Several researchers have found that some flavonoids have thyroid >> suppressive properties and they specifically inhibit deiodinase, the >enzyme >> which converts T4 to T3. Quoting one study, " Flavonoids are potent >non-toxic >> ITH (iodothyronine) deiodinase inhibitors in microsomal membranes, >and intact >> rat hepatocytes. Flavonoids are specific high affinity competitors >for >> L-T4-binding to human TBPA, weaker antagonists in the >rT3-5'deiodinase >> reaction, and very poor inhibitors of T3 binding to the nuclear T3 >receptor. >> Optimized flavonoid antagonists exhibit an ITH bio-isosteric >structure and >> conformation. " >> One flavonoid has been found which has very strong effects and is >termed >> EMD21388. In one experiment on rats, " EMD 21388 decreased plasma >thyroid >> hormone concentrations, but thyrotropin levels (TSH) in plasma and >pituitary >> did not change. Plasma clearance rates for T4 and T3 increased. >Thyroidal T4 >> secretion was diminished, but T3 secretion was elevated. >Extrathyroidal T3 >> production by 5'-deiodination was lower. T4 concentrations were >markedly >> lower in all tissues investigated. Total tissue T3 was lower in brown >adipose >> tissue, brain, cerebellum, and pituitary, tissues that express the >type II >> 5'-deiodinase isozyme due to decreased local T3 production. Most >tissues >> showed increased tissue/plasma ratios for T4 and T3. These results >indicate >> that this flavonoid diminished T4 and increased T3 secretion by the >thyroid, >> probably in analogy with other natural flavonoids, by interference >with one >> or several steps between iodide uptake, organification, and hormone >> synthesis. " >> Another study states, " Flavonoids are widely distributed in >plant-derived >> foods and possess a variety of biological activities including >antithyroid >> effects in experimental animals and humans. A structure-activity >study of 13 >> commonly consumed flavonoids was conducted to evaluate inhibition of >thyroid >> peroxidase (TPO), the enzyme that catalyzes thyroid hormone >biosynthesis. >> Most flavonoids tested were potent inhibitors of TPO, with IC50 >values >> ranging from 0.6 to 41 microM. Inhibition by the more potent >compounds, >> fisetin, kaempferol, naringenin, and quercetin, which contain a >resorcinol >> moiety, was consistent with mechanism-based inactivation of TPO as >previously >> observed for resorcinol and derivatives. " >> Two other studies showed that the grain, millet, has flavonoids >which >> have very strong antithyroid effects. The researchers were concerned >that >> the high consumption of millet in areas of Africa where iodine is >very sparse >> was a major contributor to goiter in those areas. Analysis of millet >showed >> that the active compounds may be glycosylflavones. The study states: > " At a >> concentration of 60 mumol/L, glucosylvitexin, the major >C-glycosylflavone >> present in millet, had effects comparable to those of 1 mumol/L MMI. " > MMI is >> methimazole, the antithyroidal we know as Tapazole. >> I found this particularly interesting because when I was >recovering from >> hyperT, I had just switched my breakfast grain from rice to millet. >I was >> getting progressively sicker eating rice, but once I started eating >millet I >> began to get better. I also just started taking copper, biotin and >other >> nutrients that I'm sure were important, so there is no way to tell >how >> important the millet was in my recovery. Later I switched from >millet to >> oatmeal and continued to improve. I have taken bioflavonoid >supplements and >> rutin in the past for short periods, but have taken quercetin for a >long time >> now. >> Flavonoids are important parts of the raw fruits and vegetables >that we >> eat and would seem to be indispensible parts of our diet. The highly >visible >> colors that flavonoids impart to foods may be important in >attracting the >> attention of animals. >> Given the fact that flavonoids are important for collagen >formation and >> seem to be involved in copper metabolism, I think it's important to >make sure >> that either the diet is rich in raw foods and flavonoids, or >bioflavonoids >> are supplemented. Now that I'm aware of this connection, I'll pay >more >> attention to it as I research. If you're hyper, you might want to >try millet >> for breakfast. You should purchase hulled millet and cook in the >ratio of >> one cup of millet and FOUR cups of water (that will feed about 4 >people). I >> eat it with lots of butter, a little salt, and a little honey. >Looking back >> in my diary I can see that on many days I felt much better by the end >of the >> day if I had millet for breakfast. >> >> > > >------------------------------------------------------------------------ >MyPoints-Free Rewards When You're Online. >Start with up to 150 Points for joining! >http://clickhere./click/805 > > >eGroups.com home: hyperthyroidism > - Simplifying group communications > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 6, 1999 Report Share Posted September 6, 1999 In a message dated 9/1/99 8:02:18 PM !!!First Boot!!!, growens@... writes: << Bleeding gums may or may not have anything to do with hyperthyroidism. Years ago I noticed whenever my brother came to see me from Florida and brought bushels of fresh oranges that my gums would start bleeding. Whenever I stopped eating them, my gums stopped bleeding. My dentist did not believe me, but later I read in Prevention Magazine that oranges cause some persons gums to bleed. Not long ago, I was not feeling well so I began drinking more fruit and vegetable juices, including orange juice. My gums began bleeding again. Gloria >> Hi Everyone, I thought this was interesting and it may have application to thyroid conditions. I made a strong correlation between drinking orange juice (from my own organically grown orange trees) and having hyper symptoms. I had always thought that it was from the high manganese in our soil, but after reading Gloria's letter I began to think that maybe it was from orange juice or anything acidic. I went back into my diary and it seemed that every time I had orange juice, and sometimes from tomatoes or tomato sauce, I would experience a worsening of hyper symptoms. I had never heard that oranges could make a person's gums bleed, but if bioflavonoids or something else are important in preventing bleeding gums as well as preventing hyperT, then perhaps there is something here to look at. Possibly, it is the high acidic content or the high vitamin C content without a corresponding amount of bioflavonoids. Interesting. One line of research that I've been pursuing lately concerns the alkali metals (lithium, sodium, potassium, rubidium, and cesium). It's possible that the acid/alkaline balance (the pH) of the body determines which minerals are allowed to enter the cells. Perhaps blood pH is a factor that needs to be considered. It's possible that hypers have too much acid and hypos are too alkaline. Have any other hypers made an association between highly acidic foods or oranges and hyper symptoms? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 1999 Report Share Posted September 7, 1999 , what foods or drink would be akaline for hypo's? Or do you mean that we can drink orange juice and acidic foods, but not akaline ones? Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 7, 1999 Report Share Posted September 7, 1999 Hello everyone, I have just read in an old nutrition book that the cause of thyroid problems come from everyday drugs like coffee, soda, tea and iodized salt. What it said was that 2% of the population would have problems with iodine in the salt causing health problem. Also that iodine and bromine are in the same family. Is any one allergic to bromine? I am and when I get into it, it takes a long time to heal. Bromine and chlorine are also related Bromine the uncleaner of the two. Bromine is used in hot tubs so beware. The bleeding of the gums can be stopped by eating sunflower seeds the oil in the seed is what helps. Raven BU007@... wrote: In a message dated 9/1/99 8:02:18 PM !!!First Boot!!!, growens@... writes: << Bleeding gums may or may not have anything to do with hyperthyroidism. Years ago I noticed whenever my brother came to see me from Florida and brought bushels of fresh oranges that my gums would start bleeding. Whenever I stopped eating them, my gums stopped bleeding. My dentist did not believe me, but later I read in Prevention Magazine that oranges cause some persons gums to bleed. Not long ago, I was not feeling well so I began drinking more fruit and vegetable juices, including orange juice. My gums began bleeding again. Gloria >> Hi Everyone, I thought this was interesting and it may have application to thyroid conditions. I made a strong correlation between drinking orange juice (from my own organically grown orange trees) and having hyper symptoms. I had always thought that it was from the high manganese in our soil, but after reading Gloria's letter I began to think that maybe it was from orange juice or anything acidic. I went back into my diary and it seemed that every time I had orange juice, and sometimes from tomatoes or tomato sauce, I would experience a worsening of hyper symptoms. I had never heard that oranges could make a person's gums bleed, but if bioflavonoids or something else are important in preventing bleeding gums as well as preventing hyperT, then perhaps there is something here to look at. Possibly, it is the high acidic content or the high vitamin C content without a corresponding amount of bioflavonoids. Interesting. One line of research that I've been pursuing lately concerns the alkali metals (lithium, sodium, potassium, rubidium, and cesium). It's possible that the acid/alkaline balance (the pH) of the body determines which minerals are allowed to enter the cells. Perhaps blood pH is a factor that needs to be considered. It's possible that hypers have too much acid and hypos are too alkaline. Have any other hypers made an association between highly acidic foods or oranges and hyper symptoms? eGroups.com home: hyperthyroidism www. - Simplifying group communications -- MZ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 1999 Report Share Posted September 8, 1999 In a message dated 9/7/99 7:03:26 PM !!!First Boot!!!, Ccherblady@... writes: << , what foods or drink would be akaline for hypo's? Or do you mean that we can drink orange juice and acidic foods, but not akaline ones? >> Hi I don't know if hypos should consume more acid foods and hypers consume more alkaline foods, but it seems worth experimenting with. Alkaline foods are the ones which don't taste sour. If anyone has any experiences which support or contradict this, please let us know. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 8, 1999 Report Share Posted September 8, 1999 , I know that the acid in our systems is a more ideal setting for bacteria to thrive in and Hypo patients are more incline to infections from what I have read, so I would think the Hypo types should watch out for too much acid in their diets; carbonated soda can help make your system more alkaline as I found out with my last bladder infection. I am now going Hypo as my TSH is starting to increase... Sheri Lynn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 3, 2000 Report Share Posted September 3, 2000 Hoping this will help some Kathy Flavonoids Hello Kathy: A paragraph of interest from Today's Version " of Managing Autism " . Since sulfur intake is low, and its oxidation is slow in many autistic children, sulfate is low, and PST activity is slower than it would be otherwise. It would seem that this sub optimality of sulphotransferase activity is a function of low plasma sulfate levels rather than of deficits in the actual enzyme. Thus, any foodstuff that requires or uses up sulfate ions during its metabolism, will make the situation worse. These foodstuffs include foods that supply neurotransmitters, like bananas (serotonin), chocolate (phenylethylamine), and cheese (tyramine), apple juice (and one mother reports her child drinks a quart a day!), citrus fruit juices, and paracetamol (Tylenol™). For instance, one or two minutes after a dose of Tylenol™, the entire supply of sulfate in the liver is gone! In fact, any chemicals with a high proportion of phenolic groupings will have this effect, and will enhance the problems referred to above. Many coloring materials, whether of natural or synthetic origin, possess phenolic groupings. If the PST enzyme is deficient or sulfoxidation is lacking in some 70% to 80% of autistic kids as some say, it behooves mothers to seriously heed the information in this section and to carefully guard their children from certain obvious sources of trouble. It is interesting to note Dr. Waring's statement that those with the PST /low sulfation problem have central nervous system problems from the toxic amines. For example migraine sufferers usually have low PST activity, and are readily affected by dietary " triggers " , especially those with amines, Compounds such as flavonoids (red wine and citrus fruits), inhibit PST leading to headache in the less resistant. It should be noted that many multivitamin supplements, grapeseed extract, Pycnogenol™, Quercetin, and others antioxidants contain high amounts of flavonoids. Loving you, Willis Quote Link to comment Share on other sites More sharing options...
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