Re: Re: Scared - well terrified and trying to keep it together - UPDATE

[Guest guest]

If you are going to do radiation to the breast then you might

consider various sensitizers. Those I like include vit E succinate,

quercetin, dipyridamole, carbogen with hyperthermia (although I have

not tried this with TNBC/IBC), ethacrynic acid, and PARP

inhibitors. There are various non-toxic substances that can be used

to help induce PARP cleavage. These include caffeine (and the other

xanthines), niacinamide, and curcumin. I occasionally make a very

effective one (dithiodinicotinic acid) but I wait till several people

need it at the same time because it is expensive to make and it takes

me at least a week. Five years ago I was making plenty and just

giving it away as we had private funding. Unfortunately the monies

dried up, I think mostly because the donor could not understand the

chemistry nor the importance of the compound. I wish I had saved

about ten kilos; I would wallow in it.

[Guest guest]

I did not know caffeine was a substance which could be used to induce PARP

cleavage. Are you saying it is OK to drink coffee?

Thanks

Fern

VGammill <vgammill@...> wrote:

> If you are going to do radiation to the breast then you might

> consider various sensitizers. Those I like include vit E succinate,

> quercetin, dipyridamole, carbogen with hyperthermia (although I have

> not tried this with TNBC/IBC), ethacrynic acid, and PARP

> inhibitors. There are various non-toxic substances that can be used

> to help induce PARP cleavage. These include caffeine (and the other

> xanthines), niacinamide, and curcumin. I occasionally make a very

> effective one (dithiodinicotinic acid) but I wait till several people

> need it at the same time because it is expensive to make and it takes

> me at least a week. Five years ago I was making plenty and just

> giving it away as we had private funding. Unfortunately the monies

> dried up, I think mostly because the donor could not understand the

> chemistry nor the importance of the compound. I wish I had saved

> about ten kilos; I would wallow in it.

>