Guest guest Posted April 5, 2008 Report Share Posted April 5, 2008 The kidneys are usually the first organs to show chemical damage upon uranium exposure, military manuals suggest doses or infusions of sodium bicarbonate to help alkalinize the urine if this happens. This makes the uranyl ion less kidney-toxic and promotes excretion of the nontoxic uranium-carbonate complex. The oral administration of sodium bicarbonate diminishes the severity of the changes produced by uranium in the kidneys. A study of the acidosis, blood urea, and plasma chlorides in uranium nephritis in the dog, and the protective action of sodium bicarbonate. The Journal of Experimental Medicine, Vol 25, 693-719, Copyright, 1917, by The Rockefeller Institute for Medical Research New York http://www.jem.org/cgi/content/abstract/25/5/693 Quote Link to comment Share on other sites More sharing options...
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