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Pancreatin -- do we need enteric coated or not?

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I've read several articles saying that pancreatin is destroyed in an

acidic environment, and therefore must be enteric coated, or it is

wasted.

I also just got done reading an article on the Life Extension site that

says that a Russian study showed that pancreatin is NOT NOT NOT NOT

destroyed by the acids in the stomach, and that non-enteric coated

pancreatin is better than enteric coated pancreatin because the enteric

coated pancreatin might go right through someone without being absorbed.

Who to believe, who to believe...

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How about Wobeenzym with 3 mg Chymotrypsin. 900 FIP unit ? How much

Chymotrypsin is in dr Kelley's ?........AKP

" Leonard " wrote:

What's most essential is to use a top quality brand w/a lot of

chymotrypsin (which very few brands have, except in minute

quantities).

The following the best brands I know of for healing cancer:

www.2line.com/drkelleyHOT.html (expensive; the best)

Pancreas Pork by Nutricology.com (inexpensive; used these)

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It appears the winner by huge amounts would be Univase Forte, with 45

mg of chymotrypsin per pill.

http://www.oasisadvancedwellness.com/products/univase-forte.html#1

However, these suckers are enteric coated, and there apparently is some

debate on whether this is good or bad.

>

> What's most essential is to use a top quality brand w/a lot of

> chymotrypsin (which very few brands have, except in minute

> quantities).

> The following the best brands I know of for healing cancer:

> www.2line.com/drkelleyHOT.html (expensive; the best)

> Pancreas Pork by Nutricology.com (inexpensive; used these)

>

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I should give credit to Dr. Loretta for pointing out the Univase

Forte, which she did a few weeks ago in the oleander group. She says

it is the best there is.

45 mg of chymotrypsin is HUGE, compared to the other supplements. It

would take 15 of the Wobeenzyme to match one of the Univase Forte

pills.

Perhaps an economical way to use these would be to buy the Univase

Forte for the chymotrypsin, and perhaps cheaper brands for the other,

more readily available enzymes, then take them together.

> >

> > What's most essential is to use a top quality brand w/a lot of

> > chymotrypsin (which very few brands have, except in minute

> > quantities).

> > The following the best brands I know of for healing cancer:

> > www.2line.com/drkelleyHOT.html (expensive; the best)

> > Pancreas Pork by Nutricology.com (inexpensive; used

these)

> >

>

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As far as that Russian study goes - I don't believe it. I would love to see

an English copy so if anyone has a copy please forward it to me.

All of the enzymes in pancreatin are EXTREMELY and irretrievably pH

sensitive. Once de-natured they are finished. This is an old debate. The

idea is that the enzymes are taken on a completely empty stomach and washed

through rapidly with a full glass of water. Under these conditions,

supposedly, a large percentage of the pancreatin survives the stomach. The

reason that the Germans developed the enteric coating system is precisely

because the theorized " survivability " of the pancreatin washing quickly

through the stomach didn't work out in a very large percentage of patients.

Only the shear VOLUME of (very expensive) pancreatin made them work at all.

A significant percentage of the enzymes were destroyed en route to the

target in the duodenum. These types of enzymes are simply not designed to be

exposed to strong acids or bases at any time. They operate best and achieve

their longest life when within a small pH band near neutral. Much above or

below that pH range destroys them very rapidly. The pH of the stomach rarely

goes above 2-3 and spends a significant time at pH 1. Therefore, it follows

that if the very expensive enzymes are to be delivered intact to the site

where maximum potency, life and absorption can be achieved they should be

delivered to the optimum site intact and protected from stomach acid. The

best way to do that is with a pharmaceutical grade pH sensitive (very

important) enteric coating, made of ingredients that are as close to inert

as possible. And this is what has been done with Univase Forte.

To see how quickly the coating comes off the tablet you can do a little

experiment. Take a glass of tap water and add a little baking soda. It

doesn't take much. Drop in a tablet. You can watch the coating dissolve from

the tablet. That should dispel the idea that the coatings " fail. " They

don't. And they are occasionally subjected to artificial digestive tracts

to test them. I know of NO cases where tablets have passed through

unabsorbed and that includes several users with extensively shortened

intestines. Many of these stories of " bedpan bullets " have no actual

scientific backing but are anecdotal as in " My Uncle Harry had a friend... "

kind of stuff and they get propagated on forums such as this.

The coating is a modified plant cellulose and it is soluble only in pH 6.8

and above. Since it is a cellulose product it is inert in the human system

except as fiber, which isn't a bad thing and it is in tiny quantities, just

a film over the tablet.

Hope this helps.

Be Well

Dr.L

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Good for you doc!

From: Dr. Loretta Lanphier

As far as that Russian study goes - I don't believe it. I would love to see an

English copy so if anyone has a copy please forward it to me.

All of the enzymes in pancreatin are EXTREMELY and irretrievably pH

sensitive. Once de-natured they are finished. This is an old debate. The idea is

that the enzymes are taken on a completely empty stomach and washed through

rapidly with a full glass of water. Under these conditions, supposedly, a large

percentage of the pancreatin survives the stomach. The reason that the Germans

developed the enteric coating system is precisely because the theorized

" survivability " of the pancreatin washing quickly through the stomach didn't

work out in a very large percentage of patients.

Only the shear VOLUME of (very expensive) pancreatin made them work at all. A

significant percentage of the enzymes were destroyed en route to the target in

the duodenum. These types of enzymes are simply not designed to be exposed to

strong acids or bases at any time. They operate best and achieve their longest

life when within a small pH band near neutral. Much above or below that pH range

destroys them very rapidly. The pH of the stomach rarely goes above 2-3 and

spends a significant time at pH 1. Therefore, it follows that if the very

expensive enzymes are to be delivered intact to the site where maximum potency,

life and absorption can be achieved they should be delivered to the optimum site

intact and protected from stomach acid. The best way to do that is with a

pharmaceutical grade pH sensitive (very important) enteric coating, made of

ingredients that are as close to inert as possible. And this is what has been

done with Univase Forte.

To see how quickly the coating comes off the tablet you can do a little

experiment. Take a glass of tap water and add a little baking soda. It doesn't

take much. Drop in a tablet. You can watch the coating dissolve from the tablet.

That should dispel the idea that the coatings " fail. " They don't. And they are

occasionally subjected to artificial digestive tracts to test them. I know of NO

cases where tablets have passed through unabsorbed and that includes several

users with extensively shortened intestines. Many of these stories of " bedpan

bullets " have no actual scientific backing but are anecdotal as in " My Uncle

Harry had a friend... " kind of stuff and they get propagated on forums such as

this.

The coating is a modified plant cellulose and it is soluble only in pH 6.8 and

above. Since it is a cellulose product it is inert in the human system except as

fiber, which isn't a bad thing and it is in tiny quantities, just a film over

the tablet.

Hope this helps.

Be Well

Dr.L

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>

I used 's enzyme but he refuses to reveal how much of what he

has in it, so I discontinued. I'm using the very reasonably priced

Megazyme Forte plus which has 45mg of a-chymotrypsin in it.

> It appears the winner by huge amounts would be Univase Forte, with

45

> mg of chymotrypsin per pill.

>

> http://www.oasisadvancedwellness.com/products/univase-forte.html#1

>

> However, these suckers are enteric coated, and there apparently is

some

> debate on whether this is good or bad.

>

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