Re: melanoma mets in the brain - 6-day intensive-dose lipid treatment option

[Guest guest]

Hi ,

I am a co-investigator of a clinical trial using very high oral doses of

anticancer lipids, a promising new treatment approach, and have also been

working informally with a small number of individual patients, pushing the dose

even higher and using synergistic adjunct agents. The last patient treated with

an aggressive dose had two consecutive responses of 50%, as indicated by

reliable tumor markers, with only minor and transient toxicities. This was

actually a cancer type that did not appear to be among the easiest to kill with

anticancer lipids (ovarian granulosa cell type). This is something that any

patient can pursue independently in a matter of days using potent, concentrated

agents from reliable interest sources.

Your father's case seems to be one in which an aggressive investigational option

would be worth considering closely. Whole brain radiation is highly damaging,

and also unlikely to be curative. It would only be given as a last resort in

the absence of other options. The high dose lipid therapy appears especially

promising for melanoma, which has very high levels of reactive oxygen species

and redox active iron and copper, which potentiate the anticancer activity of

the agents used. It also would work especialy well in the lipid-rich

environment of the brain (the agents used easily penetrate the blood brain

barrier). This is something he could begin in a matter of days - an intensive

6-day regimen. If it worked, tumor would be killed soon afterward, as could be

detected by a follow-up scan a month later. Given promising indications of

potential success for this treatment approach, it's particular applicability to

melanoma metastases in the brain, and the highly damaging and non-curative

character of whole brain radiation, I felt it appropriate to offer this option

to you. But let me offer the caveat up front that he would need to be in

reasonable alert and active health status to undertake this. Background

information is available at www.ufachallenge.org (username " membrane " , password

" effect " ). Feel free to contact me at davids@... for more information. -

>

> Hi all,

>

> My dad has melanoma and we just learned 3 - 1 cm spots in the brain. We meet

today to discuss whole brain radiation. What other options exist and what can

he do to reduce damage from radiation if he chooses it.

>

> He chose oral chemo in August when first diagnosed and has made some dietary

changes. He generally always ate a bit better than the SAD and has improved

this quite a bit but still no where near, organic, or truly healthy. He also

leans toward trusting the doctors. I am here because this would be my choice

and I am looking for things that he might be willing to do to enhance his life.

>

> Thanks so much,

>

>

[Guest guest]

Hi ,

I was very curious about this new treatment approach so I went through the

background info in your website. The use of high dose PUFA is most likely not

new to many in this group, particularly those who did / are doing the Budwig

protocol. Per the latter, the ideal intake is 6 tbsp flaxseed oil blended with

cottage cheese. Your approach is to take " .053 fluid ounces of flaxseed oil per

pound of body weight in US standard measurements " as is, or mixed with non-fat

yogurt. So a 100 lb person should take roughly 11 tbsp of flaxseed oil. How are

your patients doing so far with this amount of intake? I am keen to find out

because a friend who hated the taste of flaxseed oil mixed with cottage cheese

tried taking 6 tbsp of the oil straight. In an instant, she transmogrified into

an oil refinery

One tip for your patients who are like my friend, Barlean's carry lemon- and

orange-flavored flaxseed oil. This is easier to swallow than the unrefined

version.

My main question: What is the purpose of taking 200mg caffeine supplement

capsule at an hour interval in the morning? Is it possible to use pure (glorious

) coffee instead of caffeine supplement?

Thanks,

Steffi

--- " Scheim " wrote:

This is something he could begin in a matter of days - an intensive 6-day

regimen. If it worked, tumor would be killed soon afterward, as could be

detected by a follow-up scan a month later. Given promising indications of

potential success for this treatment approach, it's particular applicability to

melanoma metastases in the brain, and the highly damaging and non-curative

character of whole brain radiation, I felt it appropriate to offer this option

to you. But let me offer the caveat up front that he would need to be in

reasonable alert and active health status to undertake this. Background

information is available at www.ufachallenge.org (username " membrane " , password

" effect " )

[Guest guest]

Hi Steffi - The web site contains basic background about this high-dose lipid

approach, but does not detail specifics of progress over the past year.

Briefly, before replying to your specific questions, this approach is exciting

in its fundamentals, as a clinically predictive assay consistent with other

research shows total tumor kill for all cancer types, all patients tested with

lipids at a sufficiently high concentration. Because all agents, some common

and others highly specialized and potent, are available over the counter,

research can proceed rapidly, with significant enhancements guided by emerging

clinical results.

The bottom line is that I would not recommend what is described in the web site

as the baseline regimen to anyone at this point. There are a few active

adjuncts and some other active anticancer lipids that will significantly

increase the probability of response.

Patients so far are doing well with flaxseed oil ingestion spread out over

several hours using various blends including yogurt and flavorings. It is

essential that the oil be pure and contain no added vitamin E - efficacy is

achieved in part through damage by free radicals and lipid peroxidation products

to tumor cells. I was not familiar with the flavored Barlean's products you

mentioned and the product descriptions states that only flavors, nothing else is

added, which may be a plus for palatability. Someone trying this might get a

bottle of each and see which goes down best with several ounces.

Fasting, caffeine, and exercise boost serum free fatty acid levels about six

fold; this is needed to get serum levels of free fatty acids sufficiently high

to kill tumor. This regimen needs to be done over an intensive six-day period,

with fasting most of the time on most days. Periods of moderate exercise are

also required (but there is a clinic in Canada that could provide an IV agent

that would take the place of exercise). Coffee is fine instead of caffeine, and

it contains some polyphenols that have some anticancer activity in their own

right. For more information, feel free to email me, davids@.... -

[Guest guest]

If anyone does this please give us the results.  I cannot exercise right now.  I

am healing from hip surgery.

Thanks,  Robyn