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Re: How can we kill colon cancer stem cells?- 5- FU

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5-FU, that one sticks in my brain because of what Ralph Moss (cancer Decisions

Newsletter) overheard doctors " jokingly " refer to as, " Five Feet Under " .

That's not exactly funny and remember the old saying, " The operation was a

success but the patient died? "

I actually heard that used when I overheard one physician speaking to another

while I was a patient in a Military Hospital.

Sort of makes one wonder about the use of the word " success " in conventional

medicine. It is as the word " Response " , neither of them meaning survivability.

Then there was Kate who just asked questions regarding how to fathom through the

Quack advice out there and I suggest that conventional medicine has its quacks

and as regards cancer treatment, that means most of them. Unfortunately Kate is

correct in her concerns. There's a lot of commercialism in so-called

Alternative practices and more the reason to research and strive to get with

someone that works with cancer patients and knows what works and what does not.

Even then, nothing works for all people all the time. Nothing. In particular

I strongly abhor the approach to dealing with cancer as " simple " , because it is

not simple---but that doesn't mean we should panic and rush head-long into the

arms of the 5-FU merchants. On the contrary, we usually have the time to stop,

take a breath, and start studying. Do not accept the " you only have X number

of months to live if you don't accept my witches brew " ................keep on

trucking and looking.

Joe C.

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5 FU is blindly given by conventional oncologists to every patient

who has colon cancer. It works only for very, very few patients.

depending on the level of an enzyme in cancer cells

karla

Continued Survival of More Than Ten Years, Without Resection of Metastatic

Disease, in Patients With Metastatic Colorectal Cancer Treated With Biomodulated

Fluorouracil: Report of Two Cases

D. Leonard1 and E. Kemeny2

(1) Old School of Nursing, Waterford Regional Hospital, Waterford, Ireland

(2) Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York,

New York, USA

Published online: 14 February 2006

The treatment of metastatic colorectal cancer by chemotherapy alone was

considered palliative and without the potential to cure patients unless patients

were rendered resectable. We report two patients with metastatic colorectal

cancer involving the liver who were considered inoperable and were treated with

systemic chemotherapy using biomodulated 5-fluorouracil. Both patients received

5-fluorouracil and N-(phosphonoacetyl)-l-aspartic acid; one also received

methotrexate, leucovorin, and triacetyluridine with the

N-(phosphonoacetyl)-l-aspartic acid and 5-fluorouracil. Both patients had a

complete remission with chemotherapy and are still alive with no evidence of

cancer ten years after the diagnosis of unresectable metastatic disease. These

patients provide evidence that prolonged survival can be achieved withsystemic

chemotherapy without the use of surgery or other forms of local therapy. These

patients also confirm the importance of continued investigation of fluorouracil

modulating agents, which may further enhance the recent progress made with

fluorouracil-based combination chemotherapy for colorectal cancer.

<jcastron1@...> wrote:

>

> 5-FU, that one sticks in my brain because of what Ralph Moss (cancer Decisions

Newsletter) overheard doctors " jokingly " refer to as, " Five Feet Under " .

That's not exactly funny and remember the old saying, " The operation was a

success but the patient died? "

>

> I actually heard that used when I overheard one physician speaking to another

while I was a patient in a Military Hospital.

>

>

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