[Fwd: Re: Kanzius, Inventor of Kanzius machine, - Gold Nanorods and Nanoparticles]

[Guest guest]

I did read quite a while back about something similar used for brain

tumours.

Gold was heated in such a way that the tumour was killed without

damaging healthy tissue.

I can't find the article among my records and don't remember the name

but according to an article at this link (

http://www.sciencedaily.com/releases/2008/08/080805160209.htm ) it may

well have been nanoshells.

Gold Nanoshells Help Visibly Heat And Destroy Cancer

ScienceDaily (Aug. 6, 2008)

.. . . . a group of researchers based at the University of Texas M.D.

Cancer Center, turned to lasers and nanotechnology. They

explored an emerging minimally-invasive approach to treating tumors that

delivers a lethal dose of laser-generated heat to tumors, known as

thermal ablation. . . . . .

Working with Nanospectra Biosciences, Inc., researchers injected

nanoshells made of gold silica into canine models of brain cancer. The

nanoshells homed in on the target tumors, where they were taken in by

the tumor cells. Next, researchers irradiated the nanoparticle-filled

tumor with low-power laser light to selectively heat the tumor-but not

the surrounding, healthy tissue. M.D. researchers added

iron-oxide cores to the nanoshells to make them visible by magnetic

resonance imaging so researchers could observe the process.

Results from these experiments were supported by numerical modeling

studies, and by scanning electron microscope data showing destructive

thermal increases near the tumors' blood supplies. " Based on these

encouraging early results, we conclude that the use of magnetic

resonance temperature imaging and gold nanoshells hold the very real

possibility of meeting the long-sought goal of improving the precision

of thermal ablation, while sparing healthy tissue, " explains M.D.

Cancer Center's R.J. Stafford, Ph.D. " Temperature imaging and

guidance is an invaluable tool furthering this approach as it moves from

feasibility studies to future use in human clinical trials. "

The research was described in the talk, " Characterization of Gold

Nanoshells for Thermal Therapy Using MRI, " presented July 30, 2008 at

the 50th meeting of the American Association of Physicists in Medicine.

.......

In a similar vein (nanorods) was an article at

http://www.thaindian.com/newsportal/health1/how-gold-nanorods-help-trigger-tumou\

r-cell-death-revealed_1001512.html

which said in part:

Contrary to the assumption that cell death occurs due to the high heat

produced by the light-absorbing nanoparticles, the researchers have now

discovered that a more complex biochemical scenario is responsible for

killing the cells.

“We have found that rather than cooking the cells to death, the nanorods

first punch holes in the membrane, and cell death is then chemically

induced, in this case by an influx of calcium,” said Wei, an

associate professor of chemistry at Purdue.

The researchers have revealed that the gold rods are less than 15

nanometers wide and 50 nanometers long, or roughly 200 times smaller

than a red blood cell.

According to them, the small size of gold rods is critical for the

technology’s potential medical applications because the human immune

system quickly clears away particles larger than 100 nanometers, whereas

smaller nanoparticles can remain in the bloodstream far longer.

Shining light on the gold nanorods causes them to become extremely hot,

ionizing the molecules around them.

“This generates a plasma bubble that lasts for about a microsecond, in a

process known as cavitation. Every cavitation event is like a tiny bomb.

Then suddenly, you have a gaping hole where the nanorod was,” Wei said.

.... The study has been published in the journal Advanced Materials. (ANI)

http://www.physorg.com/news63003999.html

Has a picture of the process

When stimulated with the right frequency of laser light, a small

collection of metal nanoparticles, such as gold, can heat an area up to

1,000 times its size, according to Ohio University scientists Hugh

and Sasha Govorov.

The heating properties were observed in ice, water and a polymer shell

that was designed to mimic material in biological systems. Though the

ice did not melt when heated by low-intensity laser alone, it dissolved

once a gold nanoparticle was embedded, said the scientists, whose

findings have been published online by the journal Nano Letters.

is a professor of chemistry and Govorov is an associate

professor of theoretical physics at Ohio University. Other collaborators

in the project include Zachary Hickman, Alyssa , Wei Zhang and

Kordesch, all of Ohio University. This was dated 2006.

Rowena

jrrjim wrote:

> Have you all heard of Kanzius's invention to kill cancer? It

> involves injecting gold nano-particles into the body, which are coated

> by proteins that cancer cells will latch onto. The body is then hit

> with radio waves that heat up the gold nano particles and kill the

> cancer cells, while leaving normal cells completely alone.