Supplements of DIM Stop Many Cancers in Their Tracks

[Guest guest]

Supplements of DIM Stop Many Cancers in Their Tracks

An anti-cancer compound found in broccoli and cabbage stops breast

cancer by lowering the activity of an enzyme associated with rapidly

advancing breast cancer, according to a recent study from the University

of California, Berkley.

http://www.naturalnews.com/0258210.html

[Guest guest]

I had posiitve results in terms of being able to drive the estrogen down. I am

also on a coumadin and it appeared to conflict and reduce my thinning level. I

am just not sure if it was the Indoplex/DIM or if I may have had an additional

helping of light to moderate greens. I would rather be on DIM instead of

arimidex because of the homeopathic properties and other benefits as referenced.

The mfg said DIM did not contain vitamin K. which conflicts with blood thinners.

I may want to revisit this again and track my INR even closer.

If anyone is taking coumadin or warfarin and takes DIM please post and share if

it has affected your INR level.

>

> An interesting article for those of you using DIM to control T

> conversion to Estradiol.

>

>

> --

>

>

> Supplements of DIM Stop Many Cancers in Their Tracks

> Tuesday, March 10, 2009 by: Barbara Minton, Natural Health Editor

> http://www.naturalnews.com/025810.html

>

> (NaturalNews) An anti-cancer compound found in broccoli and cabbage stops

> breast cancer by lowering the activity of an enzyme associated with rapidly

> advancing breast cancer, according to a recent study from the University of

> California, Berkley. That compound was indole-3-carbinol (I3C). Today,

> scientists have found that diindolymethane (DIM), a molecule found in I3C,

> is the chemoprotective compound that gets the job done. According to them,

> DIM is the better choice for women wanting to halt breast cancer.

>

> DIM remains active in the body, but I3C does not

>

> Scientists at the Hackensack University Medical Center in New Jersey report

> that the recommendation for use of I3C as a weapon against cancer does not

> sufficiently consider the chemical instability of the I3C compound. They

> investigated whether I3C was directly active in its own right, or whether it

> only serves as a precursor, with all of the biological responses coming from

> some of the reaction products of I3C.

>

> They found that in the body, I3C rapidly converts into DIM, and other

> molecules. When an oral dose of I3C is taken, very little circulating I3C is

> present to effect a biological response. Because DIM provides a predictable,

> safer response than the full range of compounds derived from I3C, DIM should

> be regarded as the better choice. This study is from the July-August edition

> of the journal In Vivo.

>

> DIM stops breast cancer through hormone modulation

>

> DIM regulates hormone balance and cell behavior through its ability to

> impact the actions of hormones. The growth promoting activity of unbalanced

> estrogen can be reduced by eating cruciferous vegetables such as broccoli,

> or by taking DIM supplements. DIM is truly unique among all phytonutrients

> because it is the only one able to modify estrogen metabolism in the

> direction of greater 2-hydroxy estrogen production. Improper metabolism of

> estrogen allows for oxidation and damage to DNA. It also spurs the growth of

> estrogen sensitive cancers.

>

> Incidence of breast cancer and other estrogen related cancers is low in

> societies that consume a diet high in total vegetable content. For those

> people, DIM is gotten by regularly eating broccoli, cabbage, kale, and other

> cruciferous vegetables.

>

> When women in America have breast cancer and go to see their oncologists,

> they are never told about the link between eating cruciferous vegetables and

> halting the spread of cancer, because the Great American Cancer Machine

> refuses to acknowledge that such a link exists. They are also not told how

> easily they can halt the spread of their cancers by taking supplements of

> DIM. If women were told the truth, they could never be sold toxic treatments

> such as radiation and chemotherapy, and they would never agree to take such

> devastating drugs as Arimidex or Tamoxifen, because they would know that

> their own natural estrogen is not their enemy when it is properly balanced

> and metabolized.

>

> The truth is that eating large amounts of cruciferous vegetables or

> regularly drinking their juices can prevent cancer and stop existing cancers

> in their tracks. Anyone who does not want to eat large amounts of these

> vegetables can achieve their effects by regularly taking DIM supplements.

> DIM supplements can drastically cut the chances of cancer recurrence.

>

> Studies have shown that DIM increases the production of 2-hydroxy estrogen

> by 75% and decreases the production of 16-hydroxy estrone by 50%. This

> action creates the proper balance of estrogen to estrone so needed to halt

> cancer and prevent its recurrence.

>

> Dr. Lee will tell you what your own doctor won't

>

> Many well established risk factors for breast cancer have been correlated

> with low 2-hydroxy estrogen production, such as obesity, high fat diets, and

> diets deficient in Omega-3 fatty acids. In his book What Your Doctor May Not

> Tell You About Breast Cancer, Harvard Medical School Professor Dr. Lee

> explains the estrogen metabolic cycle and the importance of the ratio

> between 2-hydroxy and 16-hydroxy estrogen in stopping and preventing breast

> cancer.

>

> DIM is not a phytoestrogen

>

> DIM does not mimic the action of any estrogen or phytoestrogen. It has no

> inherent estrogenic activity. DIM balances the natural response to estrogen

> by adjusting the activity of metabolic enzymes and specialized estrogen

> receptor molecules. In dividing cells, the growth promoting signal from

> estrogen is limited by the reduction of the activity level of the estrogen

> receptor system. DIM's ability to promote healthy metabolic pathways for

> estrogen limits cell division and growth through influence on the cell cycle

> which determines growth and replication.

>

> DIM chokes off the blood supply from tumors

>

> In order for a cancer to grow and thrive, it must have a steady blood

> supply. Cancers create their blood supply though a process known as

> angiogenesis. Researchers have shown that DIM is able to stop tumors from

> completing angiogenesis and creating their own blood supplies. Moreover, the

> level of oxygen in tumor cells was increased by the use of DIM. Oxygen is

> the mortal enemy of cancer. Cancer can only grow and thrive in cells that

> are suffocating from lack of oxygen. A study reported in the May, 2008

> Biochemical Pharmacology Journal was the first to show that DIM can decrease

> the accumulation and activity of the key angiogenesis regulatory factor,

> HIF-1alpha, in hypoxic tumor cells.

>

> DIM makes cancer cells commit suicide

>

> Apoptosis is the appropriate death of cells. Without apoptosis, cancerous

> cells can continue to proliferate. In a study reported in the April 22, 2008

> edition of Pharmaceutical Research, scientists found low doses of DIM

> induced production of a pro-apoptotic protein in prostate cancer cells. This

> protein, known as the prostate apoptosis reponse-4 (PAR-4), reduced cancer

> cell viability and caused cell growth inhibition and apoptosis.

>

> DIM halts invasion and metastasis of cancer cells

>

> The progression and metastasis of breast and other cancers is regulated by

> the interaction between a chemokine receptor and its ligand. Organs secrete

> a particular ligand which binds to the chemokine receptor on the surface of

> primary cancer cells. This process stimulates the invasive properties of the

> cancer cells and attracts them to the preferred organ sites, creating

> metastasis. Researchers found that DIM down-regulates both the ligand and

> the receptor in breast cancer cells as well as in ovarian cancer cells. In

> their study reported in the March 28, 2008 Cancer Letter, researchers

> demonstrated that the potential of cells for chemotaxis and invasion is

> inhibited by DIM.

>

> DIM is effective against HER-2 cancers

>

> When in vitro experiments were done with breast cancer cell lines,

> researchers found that DIM inhibited the growth of all four breast cancer

> cell lines. Because two of the lines over expressed Her-2 and lacked

> estrogen receptors, these were studied in depth. DIM induced expression of

> the tumor suppressor p27 genes before the loss of cell viability and

> apoptosis, and induced transcript expression within six hours. Researchers

> in this study concluded that the effects of DIM were independent of Her-2 or

> estrogen receptor status. This study was reported in the February, 2008

> Molecular Cancer Therapeutics

>

> DIM is a powerful anti-inflammatory

>

> Recurrent and chronic inflammation has been implicated in the development of

> several kinds of cancers. As a result, researchers examined DIM's

> anti-inflammatory properties and mechanisms using stimulated macrophages.

> DIM was found to significantly decrease the release of nitric oxide,

> estradiol, tumor necrosis factor alpha, interleukin-6, and

> interleukin-1beta. They concluded that DIM inhibits the release of

> pro-inflammatory mediators in macrophages. This study can be found in the

> January, 2008 Journal of Nutrition.

>

> DIM may be nature's Viagra

>

> Estrogen is a growth promoting hormone in men as well as women. As men age,

> they begin to convert more of their testosterone into estrogen, placing

> themselves as risk of prostate cancer. DIM works the same wonder in men as

> it does in women, by blocking some of the conversion of testosterone into

> estrogen. When men are able to keep more of their testosterone, they are

> able to function sexually at a more youthful level. Erectile dysfunction is

> a symptom that testosterone is being converted to estrogen that can fuel the

> growth of prostate cancer. A man taking DIM may find his pot belly receding,

> and his morning erections returning, along with the return of more youthful

> energy levels.

>

> For more information see:

>

> http://www.sciencedaily.com/release...

>

> Bradlow HL, Review: Indole-3-carbinol as a chemoprotective agent in breast

> and prostate cancer, and Alice Jurist, Institute for medical Research,

> Hackensack University Medical Center, Hackensack, New Jersey.

>

>

> --

>

> Steve - dudescholar4@...

>

> Take World's Smallest Political Quiz at

> http://www.theadvocates.org/quiz.html

>

> " If a thousand old beliefs were ruined on our march

> to truth we must still march on. " --Stopford

>

[Guest guest]

I personally think someone on blood thinners should take supplemental K

daily AND increase their blood thinning medication to get the INR target

they are reaching for. This will I believe do at least two beneficial

things, stop the loss of bone that comes from being on blood thinning

medications (if one takes D3 in addition) and eliminate any problems

with eating vitamin K rich and healthy foods like spinach since the

amount of K in them won't be enough to make material changes in a blood

thinning/K supplementing regiment. The Life Extension Foundation had a

article on this in the past year or two along with all the benefits that

comes with the combination. They did recommend making this change in

collaboration with one's doctor.

My mother for decades took blood thinning meds and it gave her serious

osteoporosis. She was always having her INR checked and having her

medication adjusted all the time. If she had been on K supplements, her

meds wouldn't have needed to be changed all the time and she could be

comfortable knowing that her INR was consistent from week to week and

from meal to meal.

Steve

tomubl wrote:

> I had posiitve results in terms of being able to drive the estrogen down. I

am also on a coumadin and it appeared to conflict and reduce my thinning level.

I am just not sure if it was the Indoplex/DIM or if I may have had an additional

helping of light to moderate greens. I would rather be on DIM instead of

arimidex because of the homeopathic properties and other benefits as referenced.

The mfg said DIM did not contain vitamin K. which conflicts with blood thinners.

I may want to revisit this again and track my INR even closer.

>

> If anyone is taking coumadin or warfarin and takes DIM please post and share

if it has affected your INR level.

>

>

>> An interesting article for those of you using DIM to control T

>> conversion to Estradiol.

>>

>>

>> --

>>

>>

>> Supplements of DIM Stop Many Cancers in Their Tracks

>> Tuesday, March 10, 2009 by: Barbara Minton, Natural Health Editor

>> http://www.naturalnews.com/025810.html

>>

>> (NaturalNews) An anti-cancer compound found in broccoli and cabbage stops

>> breast cancer by lowering the activity of an enzyme associated with rapidly

>> advancing breast cancer, according to a recent study from the University of

>> California, Berkley. That compound was indole-3-carbinol (I3C). Today,

>> scientists have found that diindolymethane (DIM), a molecule found in I3C,

>> is the chemoprotective compound that gets the job done. According to them,

>> DIM is the better choice for women wanting to halt breast cancer.

--

Steve - dudescholar4@...

Take World's Smallest Political Quiz at

http://www.theadvocates.org/quiz.html

" If a thousand old beliefs were ruined on our march

to truth we must still march on. " --Stopford

[Guest guest]

Steve,

Actually printed the links you provide the last time. I meet with my EP next

week and will bring it to his attention. Ideally I will be able to get off

coumadin and replace with a policosanol/nattokinase combo, but until I can get

an assurance on nattokinase as a preventative thrombotic I can't take the risk.

The only concern I have about engaging the K/D3 alternative is that if I have to

compensate by increasing my coumadin dose " significantly " then I may have to

figure out a different course of action. As you may be aware coumadin and

warfarin work by retarding certain enzymes in the liver, which is something I

have had to live with, but remains a concern.

Thanks for the data. I will provide feedback once I return from my appt with my

Electrophysiologist.

Tom U

> >> An interesting article for those of you using DIM to control T

> >> conversion to Estradiol.

> >>

> >>

> >> --

> >>

> >>

> >> Supplements of DIM Stop Many Cancers in Their Tracks

> >> Tuesday, March 10, 2009 by: Barbara Minton, Natural Health Editor

> >> http://www.naturalnews.com/025810.html

> >>

> >> (NaturalNews) An anti-cancer compound found in broccoli and cabbage stops

> >> breast cancer by lowering the activity of an enzyme associated with rapidly

> >> advancing breast cancer, according to a recent study from the University of

> >> California, Berkley. That compound was indole-3-carbinol (I3C). Today,

> >> scientists have found that diindolymethane (DIM), a molecule found in I3C,

> >> is the chemoprotective compound that gets the job done. According to them,

> >> DIM is the better choice for women wanting to halt breast cancer.

>

> --

>

> Steve - dudescholar4@...

>

> Take World's Smallest Political Quiz at

> http://www.theadvocates.org/quiz.html

>

> " If a thousand old beliefs were ruined on our march

> to truth we must still march on. " --Stopford

>

[Guest guest]

Fish oil is quite a good choice as well. While aspirin prevents some

additional cardiovascular events after a heart attack/stent placement,

and the drug plavix adds at most 1 percent additional benefit to

aspirin, fish oil cuts in half future cardiovascular events, a very very

dramatic result.

The data exists on fish oil but is weak to non-existent on policosanol

and nattokinase. Almost all the studies on policosanol are Cuban

studies. Another choice is serrapeptase. Since I've had a heart

attack, I've tried everything mentioned above. Policosanol did not have

any kind of effect on my cholesterol levels although one cuban study

showed a dramatic reduction in all cause mortality in a small study. It

however has not been repeated outside of Cuba as far as I know. The

Serrapeptase and Nattokinase have potential and even thought the studies

I've found in the past are weak, I do take both of those because they

don't seem unsafe and cost is not a problem for me. I take about 2.8

grams of EPA + DHA and a full strength aspirin daily. I have taken

plavix in the past but since it's benefit is so small and it's cost is

so large not only in money but in bleeding side effects and constant

large bruising, I won't take it any more.

Of all the things I've ever taken, I've never had and INR that wasn't

exactly 1.0. I had to order those myself since my doctors didn't see a

need for these bleeding tests. I was curious since I take so many

supplements that report a blood thinning effect like vitamin E (all 8

isomers), ginkgo, etc.

For me personally, there are so many downsides to coumadin and warfarin

that I would do whatever I could to avoid them. The long term bone and

cardio issues are particularly a concern for me.

Good luck on your Dr. visit. It's rare to find a doctor that has even a

shadow of a clue about non-prescription alternatives, even when the

research is substantial.

Steve

tomubl wrote:

> Steve,

>

> Actually printed the links you provide the last time. I meet with my EP next

week and will bring it to his attention. Ideally I will be able to get off

coumadin and replace with a policosanol/nattokinase combo, but until I can get

an assurance on nattokinase as a preventative thrombotic I can't take the risk.

>

> The only concern I have about engaging the K/D3 alternative is that if I have

to compensate by increasing my coumadin dose " significantly " then I may have to

figure out a different course of action. As you may be aware coumadin and

warfarin work by retarding certain enzymes in the liver, which is something I

have had to live with, but remains a concern.

>

> Thanks for the data. I will provide feedback once I return from my appt with

my Electrophysiologist.

>

> Tom U

>

>

>

>>>> An interesting article for those of you using DIM to control T

>>>> conversion to Estradiol.

>>>>

>>>>

>>>> --

>>>>

>>>>

>>>> Supplements of DIM Stop Many Cancers in Their Tracks

>>>> Tuesday, March 10, 2009 by: Barbara Minton, Natural Health Editor

>>>> http://www.naturalnews.com/025810.html

>>>>

>>>> (NaturalNews) An anti-cancer compound found in broccoli and cabbage stops

>>>> breast cancer by lowering the activity of an enzyme associated with rapidly

>>>> advancing breast cancer, according to a recent study from the University of

>>>> California, Berkley. That compound was indole-3-carbinol (I3C). Today,

>>>> scientists have found that diindolymethane (DIM), a molecule found in I3C,

>>>> is the chemoprotective compound that gets the job done. According to them,

>>>> DIM is the better choice for women wanting to halt breast cancer.

>> --

>>

>> Steve - dudescholar4@...

--

Steve - dudescholar4@...

Take World's Smallest Political Quiz at

http://www.theadvocates.org/quiz.html

" If a thousand old beliefs were ruined on our march

to truth we must still march on. " --Stopford

[Guest guest]

On Sun, 15 Mar 2009 12:02:19 -0600, you wrote:

>Fish oil is quite a good choice as well. While aspirin prevents some

>additional cardiovascular events after a heart attack/stent placement,

>and the drug plavix adds at most 1 percent additional benefit to

>aspirin, fish oil cuts in half future cardiovascular events, a very very

>dramatic result.

DId you see the recent plavix and acid blockers study?

http://www.newsinferno.com/archives/4910

The standard practice had been acid blockers with plavix to prevent

stomach bleeds - now it's shown to be a dangerous mix.

[Guest guest]

On Sun, 15 Mar 2009 12:02:19 -0600, you wrote:

>

>For me personally, there are so many downsides to coumadin and warfarin

>that I would do whatever I could to avoid them. The long term bone and

>cardio issues are particularly a concern for me.

Blood donation helps too especially as TRT thickens blood for most

with higher hemoglobin and hematocrit. I make frequent (every 8-9

weeks) a part of the regimen.

[Guest guest]

How much blood are you giving, 500cc's?

>

> >

> >For me personally, there are so many downsides to coumadin and warfarin

> >that I would do whatever I could to avoid them. The long term bone and

> >cardio issues are particularly a concern for me.

>

>

> Blood donation helps too especially as TRT thickens blood for most

> with higher hemoglobin and hematocrit. I make frequent (every 8-9

> weeks) a part of the regimen.

>

[Guest guest]

On Mon, 16 Mar 2009 05:25:41 -0000, you wrote:

>How much blood are you giving, 500cc's?

About that.

>

>

>>

>> >

>> >For me personally, there are so many downsides to coumadin and warfarin

>> >that I would do whatever I could to avoid them. The long term bone and

>> >cardio issues are particularly a concern for me.

>>

>>

>> Blood donation helps too especially as TRT thickens blood for most

>> with higher hemoglobin and hematocrit. I make frequent (every 8-9

>> weeks) a part of the regimen.

>>

>

[Guest guest]

The fish oil is a good idea, in my opinion. When I asked a recognized expert,

his view was that 2 gm/day was sufficient and no benefit beyond that. BUT

individuals may vary in their metabolism.

Have you considered also niacin, and maintaining sufficient fiber in diet, and

exercise?

Tom

>

> Fish oil is quite a good choice as well. While aspirin prevents some

> additional cardiovascular events after a heart attack/stent placement,

> and the drug plavix adds at most 1 percent additional benefit to

> aspirin, fish oil cuts in half future cardiovascular events, a very

>

[Guest guest]

The fish oil recommendations I've seen consistently is 2.5 grams/day of

DHA+EPA, not just 2 grams of fish oil. Add up the DHA and EPA in your

fish oil gelcaps/liquid of choices to get your daily amount.

Niacin is good but it takes about 5 years of consistent consumption

before the positive mortality curve dramatically improves. I'm about at

that 5 year period.

Steve

Tom wrote:

> The fish oil is a good idea, in my opinion. When I asked a recognized expert,

his view was that 2 gm/day was sufficient and no benefit beyond that. BUT

individuals may vary in their metabolism.

> Have you considered also niacin, and maintaining sufficient fiber in diet, and

exercise?

> Tom

>

>

>> Fish oil is quite a good choice as well. While aspirin prevents some

>> additional cardiovascular events after a heart attack/stent placement,

>> and the drug plavix adds at most 1 percent additional benefit to

>> aspirin, fish oil cuts in half future cardiovascular events, a very

--

Steve - dudescholar4@...

Take World's Smallest Political Quiz at

http://www.theadvocates.org/quiz.html

" If a thousand old beliefs were ruined on our march

to truth we must still march on. " --Stopford