Guest guest Posted February 19, 2009 Report Share Posted February 19, 2009 Does anyone have info about this " natural biological compound of herbal-marine origin? karla Anticancer Effects of HESA-A in Patients With Metastatic Colon Cancer. Ahmadi A, Mohagheghi M, Karimi M, Golestanha SA, Naseri M. Background: HESA-A is a natural biological compound of herbal-marine origin. The aim of this study was to investigate the therapeutic effects of HESA-A in patients with metastatic colon cancer. METHODS: Fifty consecutive patients with end-stage colon cancer and liver metastasis at the Cancer Research Center of Tehran University of Medical Sciences were studied. Patients received HESA-A 50 mg/kg/d orally in 2 to 3 divided doses for 6 months. The patients were assessed at the start and end of the 1st, 2nd, 4th, 8th, 12th, 16th, 20th, and 26th weeks of the study. The Karnofsky Performance Scale questionnaire was completed for each patient. RESULTS: The mean Karnofsky performance score increased from 33.6 +/- 9.8 to 63.3 +/- 11 after 10 weeks of study. No significant hepatic or hematological adverse effects were seen during the study. CONCLUSION: It seems that HESA-A is an effective and safe anticancer drug, which can be used in selected patients. PMID: 19147644 [PubMed - as supplied by publisher] Related Articles Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 19, 2009 Report Share Posted February 19, 2009 Hello minolfa, HESA-A is a natural biological compound. It has shown anticancer properties in different clinical studies. HESA-A includes mineral constituents (50%), organic constituents (45%) and water (5%). The mineral constituents are a mixture of calcium carbonate, magnesium sulfate, potassium sulfate, sodium sulfate, magnesium phosphate, potassium phosphate and sodium phosphate. Low percent of other elements such as Br, Sr, Ti, Mn, Ni, As, Ag, Cu, Zn, W, Tm, Lu TI, Er, Va, Cs, Ba, Te are found in salt or complex forms in HESA-A compound. Since the extracted organic fraction of HESA-A has shown no significant effects on cancer cells, it could be suggested that the effect of this compound is due to the inorganic trace elements and / or their different complexes. In toxicological studies, HESA-A did not induce any biochemical, hematological or histopathological signs of toxicity and an oral dose of 5000 mg/kg was estimated as no-observed-adverse-effect-level (NOAEL) for mice and rats. We recommend further studies to understand the exact mechanisms of action of HESA-A and evaluate its long-term effects on the survival of patients and their quality of life. Mike Thursday, February 19, 2009, 4:29:38 PM, you wrote: m> Does anyone have info about this " natural biological compound of m> herbal-marine origin? m> karla m> Anticancer Effects of HESA-A in Patients With Metastatic Colon Cancer. m> Ahmadi A, Mohagheghi M, Karimi M, Golestanha SA, Naseri M. m> Background: HESA-A is a natural biological compound of herbal-marine m> origin. The aim of this study was to investigate the therapeutic Quote Link to comment Share on other sites More sharing options...
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