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Re: immune update/synergists

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Most chemos trash the immune system. Usually monoclonal antibodies

are ok. Vincristine and bleomycin have many side effects but they do

spare immune function. Vinblastine though will damage immune

function. If your goal is to spare immune function with chemo there

are many strategies which will allow a much lower dose. These

include IPT, chronotherapy, and the use of a variety of synergists

such as pleuronic, mitoguazone, pentamidine (with benzimidazole), and

SAHA. By using extremely low doses you can get away from using those

protocols that use steroidal anti-inflammatories such as dexamethasone.

Other drugs/supplements that can kick up chemo and/or reduce drug

resistance include hydralazine with valproate acid, verapamil with

disulfiram, ketakonazole, BSO, sanguinarine, progesterone, EGCG,

caffeine, melatonin, Vit C with K3, pau d'arco, along with many others.

There are many strategies to kick up the effectiveness of a cancer

vaccine. One is to use very low doses of cyclophosphamide prior the

injections, next pick an adjuvant that will steer the vaccine in a

Th1 direction. It is better to inject multiple intradermal

injections in the inguinal area because of much better exposure to

the antigen presenting cells (APC, dendritic cells) in the skin and

because of the proximity to the inguinal lymphatic chains. Both IL-2

and GM-CSF are useful, and as I mentioned earlier Viagra and

Ribavirin seem to be quite useful in kicking up the right type of

immune response.

All of these things are available, but I have stopped making SAHA

because of the expense. Pleuronic might kick up chemotherapy a

thousand fold in lab research but I haven't used it.

In general I like vaccines -- especially targeting subunit

vaccines. I have many years of experience with these. In general I

do not like chemotherapy. I have seen too many tumors shrink only to

see them grow again. Sometimes it is necessary to do what you have

to do stop a tumor in its tracks and give the immune system a chance

to work. This always includes doing the things that

In our one-week retreat program (Del Mar, California) we give

seminars on the use of these meds and try to help provide sources for

these things. We are trying to set up a service that can make

hard-to-find meds/supplements readily available, including outside the US.

858-922-7410

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