Guest guest Posted February 28, 2009 Report Share Posted February 28, 2009 This from 's Hopkins Pathology: How accurate is a CA-125 test for ovarian cancer? The CA-125 test only returns a true positive result for about 50% of Stage I ovarian cancer patients. The CA-125 test is not an adequate early detection tool when used alone. The CA-125 test has an 80% chance of returning true positive results from stage II, III, and IV ovarian cancer patients. The other 20% of ovarian cancer patients do not show any increase in CA-125 concentrations. However several women's reproductive disorders can cause a false positive result. Endometriosis, benign ovarian cysts, first trimester of pregnancy, and pelvic inflammatory disease all produce higher levels of CA-125. 70% of people with cirrhosis, 60% of people with pancreatic cancer, and 20%-25% of people with other malignancies have elevated levels of CA-125. A study of about 22,000 post menopausal women 45 years or older screened about 11,000 with the CA-125 test. 468 patients with elevated CA-125 levels were given an ultrasonography test. Of those patients, 29 underwent surgical procedures. 6 had ovarian cancers, 2 had adenocarcinoma of unknown origin, 14 had benign tumors, 4 had fibroids, and 3 had no abnormalities. CA-125 test has a lower specificity in premenopausal women than postmenopausal women. The CA-125 test is not recommended for use alone as an early detection method. The rate of false positives is very high, and there has been no data concerning change in mortality. The CA-125 test should not be used alone to detect ovarian 'There was more but anyone interested can do their own research which, by the way, is what we should all be doing and not relying upon the list for the 'end word' on anything. Sure, pick one-another's brains but you'll sometimes get information that may not apply to you. The list will, however, get you to research and that alone is worth being a member of Cancercured. Then every now and then Gammill, Director of The Center for The Study Of Natural Oncology will pop up and give some 'heavy' information for us to digest. Joe C. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 28, 2009 Report Share Posted February 28, 2009 > Then every now and then Gammill, Director of The Center for The Study Of Natural Oncology will pop up and give some 'heavy' information for us to digest. > is currently trying to figure out how to kick my CA125 into submission. It was 171 a month ago and is now 354. And oh, by the way, I do NOT have ovarian cancer. My dx is breast, but with mets to the peritoneum (which acts like ov ca) and bone. xxoo Quote Link to comment Share on other sites More sharing options...
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