Guest guest Posted May 10, 2003 Report Share Posted May 10, 2003 In a message dated 5/10/03 1:37:43 PM Eastern Daylight Time, arnoldgore@... writes: > <A HREF= " www.iptq.org " >www.iptq.org</A> > Could this turn out to be an effective treatment for SARS? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 10, 2003 Report Share Posted May 10, 2003 In a message dated 5/10/03 1:37:43 PM Eastern Daylight Time, arnoldgore@... writes: > <A HREF= " www.iptq.org " >www.iptq.org</A> > Could this turn out to be an effective treatment for SARS? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 10, 2003 Report Share Posted May 10, 2003 ----- Original Message ----- > Could this turn out to be an effective treatment for SARS? > IPT is an unlikely strategy for effectively dealing with SARS. As concerns the successful use of IVIG for SARS as shown in the three PRs below, in the 4/03 Nature Medicine article titled " F(ab)'(2)-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins, " Basta et al. state: " The working hypothesis of this study was that therapeutic doses of exogenous immunoglobulins would functionally inactivate C3a and C5a. We show that C3a and C5a seem to bind to immunoglobulin molecules through the constant region of F(ab)'(2) fragments. This interaction inhibits anaphylatoxin-induced pro-inflammatory events in vitro and in vivo. " --------------------------- http://www.dailytelegraph.co.uk/news/main.jhtml?xml=/news/2003/05/11/wsars11 ..x ml & sSheet=/news/2003/05/11/ixworld.html Daily Telegraph, UK Doctor finds 'blood serum cure for Sars' By Adam Luck in Hong Kong (Filed: 11/05/2003) A doctor in Hong Kong who survived Sudden Acute Respiratory Syndrome is pioneering a treatment based on his own blood to help patients who do not respond to conventional anti-viral drugs. Prof Cheng claims a success rate of more than 60 per cent for the experimental treatment for Sars, which has killed 526 people throughout the world. It involves giving patients a transfusion of serum produced from blood donated by recovering Sars sufferers, who appear to have built up antibodies after being exposed to the virus. So far 70 patients have been treated with the convalescent serum and most showed rapid improvement within days. With the mortality rate rising to an estimated 50 per cent among older patients - who are less likely to respond to conventional treatment - Prof Cheng is optimistic that his therapy could become an alternative treatment. " This was an unproven and unknown treatment, " said Prof Cheng, of the Department of Medicine at Hong Kong's Chinese University, " but at the time we had patients deteriorating in front of our eyes and this was a logical alternative. " I felt that it was justifiable and we explained the risks involved to the patients and their relatives. We are very pleased with how it has gone. Obviously, this is in its early stages but the results have been very encouraging. " Not only has this helped patients who have been beyond the help of the conventional treatment but many new Sars patients are now asking to be treated by this method. " The transfusions are performed during the second week of infection when the Sars virus is at its peak and victims are most vulnerable. In some cases, patients have received several transfusions. Although not all those treated with the serum have recovered none has died so far. " They just take longer to recover or are still in hospital, " said Prof Cheng. Until now, doctors in Hong Kong - which is leading the Sars treatment - have relied on a cocktail of Ribavirin - which represses viruses - and steroids to help patients. Potential side effects include damage to the heart, liver and blood and also deformities in unborn children. So far the treatment using serum - which is blood stripped of its red and white blood cells - has produced no obvious side effects. Prof Cheng, who is based at the Prince of Wales Hospital in Kowloon, said that tackling Sars with convalescent serum was a logical extension of existing techniques. Serum that is rich in antibodies is already used to treat viral infections such as hepatitis B and HIV. But whereas most serum is produced to internationally accepted standards and carefully filtered for other dangerous viruses, the Hong Kong team could not guarantee a uniform amount of antibodies in each transfusion. However, Prof Cheng decided that the risk was " justifiable " . He said: " We tried the treatment on a couple of our colleagues and some did have a quite quick recovery rate. Although this was not a controlled trial we felt encouraged and began to use it more. " We need to complete experiments to document the viral infection and compare this between a treatment group and those who have not been given the serum treatment. " --------------------------- http://www.heraldsun.news.com.au/printpage/0,5481,6392231,00.html Melbourne Herald Sun 06may03 DOCTORS in Hong Kong say they have helped some seriously ill SARS patients by giving them a last-resort treatment using serum that contains antibodies to the virus, radio reported. Hong Kong hospitals have typically prescribed a combination of the antiviral drug ribavirin and steroids for SARS, but some patients who did not respond to that regimen have got serum from patients who have recovered and developed antibodies. " This treatment has only been applied to those critically ill patients when everything else fails, " Janet Chow, a spokeswoman for the medical faculty at the Chinese University of Hong Kong, said. " It is used as an alternative treatment. " Hong Kong has reported 1637 cases of severe acute respiratory syndrome, and 187 deaths. Government-owned radio RTHK said about 50 patients at the hard-hit Prince of Wales Hospital had been treated with the serum and the results had been good. RTHK said the patients had generally recovered and left the hospital more quickly, with a lower mortality rate. The radio report did not provide statistics, but Chinese University researchers were to discuss the results later today at a news conference. Dr ph Sung, head of the university's Department of Medicine, told RTHK it was best to treat patients with the serum within two weeks of the onset of SARS since the antibody could suppress the virus, which developed fastest in the early stages. Hong Kong's government said yesterday it planned to set up a Centre for the Prevention and Control of Infectious Diseases, a local version of the US-based CDC. The Hong Kong Jockey Club, which holds a monopoly on horse racing and lottery games in Hong Kong and gives all proceeds to charity, has agreed in principle to donate 500 million Hong Kong dollars ($100 million)) for the centre. But Dr Leung Ping-chung, an orthopedic and traumatology professor who has been monitoring SARS cases, expressed worries today that the centre might end up overlapping with some functions now performed by the territory's Health Department. --------------------------- http://www.etaiwannews.com/Taiwan/2003/04/23/1051059498.htm Taiwan Specialist criticizes DOH over SARS procedures 2003-04-23 / Taiwan News, Staff Reporter / By Taijing Wu One of 17 specialists from the SARS cases inspection committee, Professor Chen Chien-jen ( Ø´ÿ§Ø) (µ{´ÿ§H) responded to complaints from the chief of the Taipei City Government's Department of Health Chiou Shu-ti (TÙ Qÿ ) by saying that the work in the fight against SARS involves a process of learning scientific and democratic approaches to problem solving. Chiou complained on April 21 that the Executive Yuan's Department of Health changes its mind too many times on what norms to apply for determining the status of reported cases. Whether SARS cases are considered probable or suspected switches too many times in a day. Chiou said that this causes big problems for health departments under the committee, because they have to adopt their restrictions and policies based on the rulings of the highest department. Professor Chen said, " Since we live in a democratic society, then any conclusion reached must be discussed first before coming to the decision. There are 17 specialists meeting together every working day to discuss the probability that a reported case is or is not a probable case according to the patient's travel and medical records. The reason why we have to discuss every case is because we still do not have an 100 percent effective pharmaceutical test to determine if a reported case is or is not infected by the SARS virus. " Professor Chen also urged that the decisions made by the 17 specialists from the SARS cases inspection committee be respected. " It is very important that people report any cases with symptoms stemming from the respiratory system. And travel records are even more important for they should be as detailed as possible including all those that the reported case has been in contact with, " Chen said. However, as for an efficient way to treat patients with symptoms of having the SARS virus, the Cathay General Hospital announced yesterday that they had succeeded in curing a patient with Intravenous Immunoglobulin, also know as IVIG, taken from the blood of Taiwanese donors. Doctor Huang Cheng-hua from the Cathay General Hospital who treated such a patient said, " The patient's Lactic Dehydrogenase (LDG) went down as soon as he was injected with IVIG. The reason why I took IVIG from the blood of local donors is because the SARS virus originates from China, and Taiwan donors are the most similar hosts in terms of characteristics to Chinese carriers. " Lactic Dehydrogenase is a type of hormone secreted by the lungs when its cells are wounded. Patients with SARS have injured lungs, therefore their lungs secrete LDH. That patient had been hospitalized on April 1, and at the time, an X-ray report did not show any signs of abnormalities yet. When on April 5, the patient began to have a high fever with gasping breath, he was injected with IVIG. " Before doing so, we (the Cathay General Hospital) solicited advice from the National Taiwan University Hospital. They also told us to use IVIG, but were not precise in what kind to use, " said Dr. Huang. --------------------------- Basta M, Van Goor F, Luccioli S, Billings EM, Vortmeyer AO, Baranyi L, Szebeni J, Alving CR, Carroll MC, Berkower I, Stojilkovic SS, Metcalfe DD. F(ab)'(2)-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. Nat Med 2003 Apr;9(4):431-8. Neuronal Excitability Section, National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, land, USA. Email: mb29r@... Abstract: High-dose intravenous immunoglobulin (IVIG) prevents immune damage by scavenging complement fragments C3b and C4b. We tested the hypothesis that exogenous immunoglobulin molecules also bind anaphylatoxins C3a and C5a, thereby neutralizing their pro-inflammatory effects. Single-cell calcium measurements in HMC-1 human mast cells showed that a rise in intracellular calcium caused by C3a and C5a was inhibited in a concentration-dependent manner by IVIG, F(ab)'(2)-IVIG and irrelevant human monoclonal antibody. C3a- and C5a-induced thromboxane (TXB(2)) generation and histamine release from HMC-1 cells and whole-blood basophils were also suppressed by exogenous immunoglobulins. In a mouse model of asthma, immunoglobulin treatment reduced cellular migration to the lung. Lethal C5a-mediated circulatory collapse in pigs was prevented by pretreatment with F(ab)'(2)-IVIG. Molecular modeling, surface plasmon resonance (SPR) and western blot analyses suggested a physical association between anaphylatoxins and the constant region of F(ab)'(2). This binding could interfere with the role of C3a and C5a in inflammation. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 10, 2003 Report Share Posted May 10, 2003 ----- Original Message ----- > Could this turn out to be an effective treatment for SARS? > IPT is an unlikely strategy for effectively dealing with SARS. As concerns the successful use of IVIG for SARS as shown in the three PRs below, in the 4/03 Nature Medicine article titled " F(ab)'(2)-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins, " Basta et al. state: " The working hypothesis of this study was that therapeutic doses of exogenous immunoglobulins would functionally inactivate C3a and C5a. We show that C3a and C5a seem to bind to immunoglobulin molecules through the constant region of F(ab)'(2) fragments. This interaction inhibits anaphylatoxin-induced pro-inflammatory events in vitro and in vivo. " --------------------------- http://www.dailytelegraph.co.uk/news/main.jhtml?xml=/news/2003/05/11/wsars11 ..x ml & sSheet=/news/2003/05/11/ixworld.html Daily Telegraph, UK Doctor finds 'blood serum cure for Sars' By Adam Luck in Hong Kong (Filed: 11/05/2003) A doctor in Hong Kong who survived Sudden Acute Respiratory Syndrome is pioneering a treatment based on his own blood to help patients who do not respond to conventional anti-viral drugs. Prof Cheng claims a success rate of more than 60 per cent for the experimental treatment for Sars, which has killed 526 people throughout the world. It involves giving patients a transfusion of serum produced from blood donated by recovering Sars sufferers, who appear to have built up antibodies after being exposed to the virus. So far 70 patients have been treated with the convalescent serum and most showed rapid improvement within days. With the mortality rate rising to an estimated 50 per cent among older patients - who are less likely to respond to conventional treatment - Prof Cheng is optimistic that his therapy could become an alternative treatment. " This was an unproven and unknown treatment, " said Prof Cheng, of the Department of Medicine at Hong Kong's Chinese University, " but at the time we had patients deteriorating in front of our eyes and this was a logical alternative. " I felt that it was justifiable and we explained the risks involved to the patients and their relatives. We are very pleased with how it has gone. Obviously, this is in its early stages but the results have been very encouraging. " Not only has this helped patients who have been beyond the help of the conventional treatment but many new Sars patients are now asking to be treated by this method. " The transfusions are performed during the second week of infection when the Sars virus is at its peak and victims are most vulnerable. In some cases, patients have received several transfusions. Although not all those treated with the serum have recovered none has died so far. " They just take longer to recover or are still in hospital, " said Prof Cheng. Until now, doctors in Hong Kong - which is leading the Sars treatment - have relied on a cocktail of Ribavirin - which represses viruses - and steroids to help patients. Potential side effects include damage to the heart, liver and blood and also deformities in unborn children. So far the treatment using serum - which is blood stripped of its red and white blood cells - has produced no obvious side effects. Prof Cheng, who is based at the Prince of Wales Hospital in Kowloon, said that tackling Sars with convalescent serum was a logical extension of existing techniques. Serum that is rich in antibodies is already used to treat viral infections such as hepatitis B and HIV. But whereas most serum is produced to internationally accepted standards and carefully filtered for other dangerous viruses, the Hong Kong team could not guarantee a uniform amount of antibodies in each transfusion. However, Prof Cheng decided that the risk was " justifiable " . He said: " We tried the treatment on a couple of our colleagues and some did have a quite quick recovery rate. Although this was not a controlled trial we felt encouraged and began to use it more. " We need to complete experiments to document the viral infection and compare this between a treatment group and those who have not been given the serum treatment. " --------------------------- http://www.heraldsun.news.com.au/printpage/0,5481,6392231,00.html Melbourne Herald Sun 06may03 DOCTORS in Hong Kong say they have helped some seriously ill SARS patients by giving them a last-resort treatment using serum that contains antibodies to the virus, radio reported. Hong Kong hospitals have typically prescribed a combination of the antiviral drug ribavirin and steroids for SARS, but some patients who did not respond to that regimen have got serum from patients who have recovered and developed antibodies. " This treatment has only been applied to those critically ill patients when everything else fails, " Janet Chow, a spokeswoman for the medical faculty at the Chinese University of Hong Kong, said. " It is used as an alternative treatment. " Hong Kong has reported 1637 cases of severe acute respiratory syndrome, and 187 deaths. Government-owned radio RTHK said about 50 patients at the hard-hit Prince of Wales Hospital had been treated with the serum and the results had been good. RTHK said the patients had generally recovered and left the hospital more quickly, with a lower mortality rate. The radio report did not provide statistics, but Chinese University researchers were to discuss the results later today at a news conference. Dr ph Sung, head of the university's Department of Medicine, told RTHK it was best to treat patients with the serum within two weeks of the onset of SARS since the antibody could suppress the virus, which developed fastest in the early stages. Hong Kong's government said yesterday it planned to set up a Centre for the Prevention and Control of Infectious Diseases, a local version of the US-based CDC. The Hong Kong Jockey Club, which holds a monopoly on horse racing and lottery games in Hong Kong and gives all proceeds to charity, has agreed in principle to donate 500 million Hong Kong dollars ($100 million)) for the centre. But Dr Leung Ping-chung, an orthopedic and traumatology professor who has been monitoring SARS cases, expressed worries today that the centre might end up overlapping with some functions now performed by the territory's Health Department. --------------------------- http://www.etaiwannews.com/Taiwan/2003/04/23/1051059498.htm Taiwan Specialist criticizes DOH over SARS procedures 2003-04-23 / Taiwan News, Staff Reporter / By Taijing Wu One of 17 specialists from the SARS cases inspection committee, Professor Chen Chien-jen ( Ø´ÿ§Ø) (µ{´ÿ§H) responded to complaints from the chief of the Taipei City Government's Department of Health Chiou Shu-ti (TÙ Qÿ ) by saying that the work in the fight against SARS involves a process of learning scientific and democratic approaches to problem solving. Chiou complained on April 21 that the Executive Yuan's Department of Health changes its mind too many times on what norms to apply for determining the status of reported cases. Whether SARS cases are considered probable or suspected switches too many times in a day. Chiou said that this causes big problems for health departments under the committee, because they have to adopt their restrictions and policies based on the rulings of the highest department. Professor Chen said, " Since we live in a democratic society, then any conclusion reached must be discussed first before coming to the decision. There are 17 specialists meeting together every working day to discuss the probability that a reported case is or is not a probable case according to the patient's travel and medical records. The reason why we have to discuss every case is because we still do not have an 100 percent effective pharmaceutical test to determine if a reported case is or is not infected by the SARS virus. " Professor Chen also urged that the decisions made by the 17 specialists from the SARS cases inspection committee be respected. " It is very important that people report any cases with symptoms stemming from the respiratory system. And travel records are even more important for they should be as detailed as possible including all those that the reported case has been in contact with, " Chen said. However, as for an efficient way to treat patients with symptoms of having the SARS virus, the Cathay General Hospital announced yesterday that they had succeeded in curing a patient with Intravenous Immunoglobulin, also know as IVIG, taken from the blood of Taiwanese donors. Doctor Huang Cheng-hua from the Cathay General Hospital who treated such a patient said, " The patient's Lactic Dehydrogenase (LDG) went down as soon as he was injected with IVIG. The reason why I took IVIG from the blood of local donors is because the SARS virus originates from China, and Taiwan donors are the most similar hosts in terms of characteristics to Chinese carriers. " Lactic Dehydrogenase is a type of hormone secreted by the lungs when its cells are wounded. Patients with SARS have injured lungs, therefore their lungs secrete LDH. That patient had been hospitalized on April 1, and at the time, an X-ray report did not show any signs of abnormalities yet. When on April 5, the patient began to have a high fever with gasping breath, he was injected with IVIG. " Before doing so, we (the Cathay General Hospital) solicited advice from the National Taiwan University Hospital. They also told us to use IVIG, but were not precise in what kind to use, " said Dr. Huang. --------------------------- Basta M, Van Goor F, Luccioli S, Billings EM, Vortmeyer AO, Baranyi L, Szebeni J, Alving CR, Carroll MC, Berkower I, Stojilkovic SS, Metcalfe DD. F(ab)'(2)-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. Nat Med 2003 Apr;9(4):431-8. Neuronal Excitability Section, National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, land, USA. Email: mb29r@... Abstract: High-dose intravenous immunoglobulin (IVIG) prevents immune damage by scavenging complement fragments C3b and C4b. We tested the hypothesis that exogenous immunoglobulin molecules also bind anaphylatoxins C3a and C5a, thereby neutralizing their pro-inflammatory effects. Single-cell calcium measurements in HMC-1 human mast cells showed that a rise in intracellular calcium caused by C3a and C5a was inhibited in a concentration-dependent manner by IVIG, F(ab)'(2)-IVIG and irrelevant human monoclonal antibody. C3a- and C5a-induced thromboxane (TXB(2)) generation and histamine release from HMC-1 cells and whole-blood basophils were also suppressed by exogenous immunoglobulins. In a mouse model of asthma, immunoglobulin treatment reduced cellular migration to the lung. Lethal C5a-mediated circulatory collapse in pigs was prevented by pretreatment with F(ab)'(2)-IVIG. Molecular modeling, surface plasmon resonance (SPR) and western blot analyses suggested a physical association between anaphylatoxins and the constant region of F(ab)'(2). This binding could interfere with the role of C3a and C5a in inflammation. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2003 Report Share Posted May 26, 2003 Dr. Ayre has a web site now: contemporarymedicine.com The list of IPT practitioners is available at iptq.org > Dr. Donato ,MD of Tjuana,Mexico has been using IPT successfully > for 20 years according to an article by Dr. Rowen,MD in his newsletter > Second Opinoin. He slso cites Dr. Ayre a pioneer teacher of the IPT > therapy.He can provide a list of practitioners for $5.00(may be outdated) and > a Self addressed stamped envelope to: > Contemporary Medicine > 322 Burr Ridge Parkwa > Burr Ridge,IL 60521 > also look up <A HREF= " www.iptq.org " >www.iptq.org</A> > arnold > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2003 Report Share Posted May 26, 2003 Dr. Ayre has a web site now: contemporarymedicine.com The list of IPT practitioners is available at iptq.org > Dr. Donato ,MD of Tjuana,Mexico has been using IPT successfully > for 20 years according to an article by Dr. Rowen,MD in his newsletter > Second Opinoin. He slso cites Dr. Ayre a pioneer teacher of the IPT > therapy.He can provide a list of practitioners for $5.00(may be outdated) and > a Self addressed stamped envelope to: > Contemporary Medicine > 322 Burr Ridge Parkwa > Burr Ridge,IL 60521 > also look up <A HREF= " www.iptq.org " >www.iptq.org</A> > arnold > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2003 Report Share Posted May 26, 2003 Thanks for your input, it is very helpful. Your tumor shrinkage is very encouraging. My cancer started out as a base of tongue with a metastasis to a lymph node in the neck. It was diagnosed as squamous cell carcinoma SCC in Feb 2001. I had treatment then, radiation for 35 sessions, regular chemo with carboplatin and taxol and a neck dissection. It was very difficult; but the tumors were gone. Did you have SCC, and if so, what chemo did you use? It then spread to my T5 spine and biopsied as SCC again. Treated with radiation for 20 low dose sessions with pain relief. The really bad news came when a CT scan in Sept 2002 showed it had spread to both lungs. SCC is assumed now. It has been growing since. I've tried Iressa, CLT a form of photodynamis therapy( a waste), and nutrition. I am scheduled to begin IPT with Dr. Lodi in Glen Cove LI, NY. He is on the website www.iptq.com you mentioned. I saw him and was favorably impressed. He said he would research what chemo to start with using the network of IPT providers. Thanks again for your response, I will check out his website. DeLuca sitzfamily <sitzfamily@...> wrote: Dr. Ayre has a web site now: contemporarymedicine.com The list of IPT practitioners is available at iptq.org > Dr. Donato ,MD of Tjuana,Mexico has been using IPT successfully > for 20 years according to an article by Dr. Rowen,MD in his newsletter > Second Opinoin. He slso cites Dr. Ayre a pioneer teacher of the IPT > therapy.He can provide a list of practitioners for $5.00(may be outdated) and > a Self addressed stamped envelope to: > Contemporary Medicine > 322 Burr Ridge Parkwa > Burr Ridge,IL 60521 > also look up <A HREF= " www.iptq.org " >www.iptq.org</A> > arnold > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 26, 2003 Report Share Posted May 26, 2003 Thanks for your input, it is very helpful. Your tumor shrinkage is very encouraging. My cancer started out as a base of tongue with a metastasis to a lymph node in the neck. It was diagnosed as squamous cell carcinoma SCC in Feb 2001. I had treatment then, radiation for 35 sessions, regular chemo with carboplatin and taxol and a neck dissection. It was very difficult; but the tumors were gone. Did you have SCC, and if so, what chemo did you use? It then spread to my T5 spine and biopsied as SCC again. Treated with radiation for 20 low dose sessions with pain relief. The really bad news came when a CT scan in Sept 2002 showed it had spread to both lungs. SCC is assumed now. It has been growing since. I've tried Iressa, CLT a form of photodynamis therapy( a waste), and nutrition. I am scheduled to begin IPT with Dr. Lodi in Glen Cove LI, NY. He is on the website www.iptq.com you mentioned. I saw him and was favorably impressed. He said he would research what chemo to start with using the network of IPT providers. Thanks again for your response, I will check out his website. DeLuca sitzfamily <sitzfamily@...> wrote: Dr. Ayre has a web site now: contemporarymedicine.com The list of IPT practitioners is available at iptq.org > Dr. Donato ,MD of Tjuana,Mexico has been using IPT successfully > for 20 years according to an article by Dr. Rowen,MD in his newsletter > Second Opinoin. He slso cites Dr. Ayre a pioneer teacher of the IPT > therapy.He can provide a list of practitioners for $5.00(may be outdated) and > a Self addressed stamped envelope to: > Contemporary Medicine > 322 Burr Ridge Parkwa > Burr Ridge,IL 60521 > also look up <A HREF= " www.iptq.org " >www.iptq.org</A> > arnold > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 31, 2003 Report Share Posted October 31, 2003 I've been through a course if IPT (Insulin Potentiation Therapy) at a holistic medical clinic here in Clearwater FL so I can relate my experiences. I was diagnosed with prostate cancer about 6 years ago with a PSA of 125. A combination of Lupron, herbal treatments, and mental-spiritual counseling brought the PSA down to 0.05 where it stayed for a few years. Due to loss of health insurance I had stopped taking Lupron for half a year and my PSA shot up to 80. The IPT treatment was very easy to go through. They first muscle tested me to see which chemo would be the best. Then they weighed me to calculate the dose of insulin. Then, while lying down they gave me the insulin via an I.V. line. Someone stayed with me, periodically checking my blood sugar. Then, when it was in range they gave me the chemo via the I.V. followed by glucose to bring the blood sugar back up. They also gave me some sweets to eat. When the blood sugar was back in range and I was back to normal I was allowed to get up and go home. Some evenings I had some nausea. Sometimes I threw up once or twice. After that I was fine. Other times I didn't even have nausea. That was the sum total of the side effects. Hair still in. Completely back to normal after a night's sleep. I went through two runs of a half dozen treatments. My PSA came back down dramatically. Not to normal but much lower. So it does work on stage IV as well. Medicare paid for the administration costs but not for the chemicals. Recently my PSA has gone way up and my femur was taken over by cancer. After an operation to put a pin in the femur and radiation treatment my leg is getting back to normal. A few days ago I saw an oncologist who specializes in chemo. He was very honest. He recommended chemo but said that chemo only had a 20% chance of getting rid of the cancer. I told him about IPT. He had never heard of it and said it was not a recognized treatment. I said my holistic doctor was not a " one size fits all " alternative specialist but would not hesitate to recommend regular medical treatment, including regular chemo if indicated. He said in that case it would be ok to do IPT. He agreed it would be an easier path. As soon as I get out of the rehabilitation hospital I will immediately start another course of IPT. I am definitely in favor of IPT, particularly when I hear the horror stories of the side effects of regular chemo. I would definitely recommend IPT for anyone, particularly as the first step in treatment. It is definitely a smoother gradient, particularly for an older person. And it doesn't rule out regular treatment later if wanted. Phil ----- Original Message ----- From: Judy Silverman <maturelady1@...> >Read a lot about IPT - it does work a lot better than standard chemo. Cancer thrives on sugar - glucose level is lowered, cancer loses its permeability, then 10% of normal chemo is introduced into body with glucose and other things and cancer sucks just about all of it up because it needs the glucose to survive - and there are very few if any side effects because your good cells do not poisoned. It works best with stage I and II. --- Sharon Fan <shinyu_fan@...> wrote: > > Has anyone had any experience with Insulin > Potentiation Therapy (IPT)? > My mom is 77 years old and was diagnosed with stage > II breast cancer. I > thought this low-dose chemotherapy may be a better > option for her than > the traditional chemo. > > If anyone had any personal experience, or have any > advice, I'd really > appreciate if you don't mind sharing it with me. > Shinyu Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 31, 2003 Report Share Posted October 31, 2003 I've been through a course if IPT (Insulin Potentiation Therapy) at a holistic medical clinic here in Clearwater FL so I can relate my experiences. I was diagnosed with prostate cancer about 6 years ago with a PSA of 125. A combination of Lupron, herbal treatments, and mental-spiritual counseling brought the PSA down to 0.05 where it stayed for a few years. Due to loss of health insurance I had stopped taking Lupron for half a year and my PSA shot up to 80. The IPT treatment was very easy to go through. They first muscle tested me to see which chemo would be the best. Then they weighed me to calculate the dose of insulin. Then, while lying down they gave me the insulin via an I.V. line. Someone stayed with me, periodically checking my blood sugar. Then, when it was in range they gave me the chemo via the I.V. followed by glucose to bring the blood sugar back up. They also gave me some sweets to eat. When the blood sugar was back in range and I was back to normal I was allowed to get up and go home. Some evenings I had some nausea. Sometimes I threw up once or twice. After that I was fine. Other times I didn't even have nausea. That was the sum total of the side effects. Hair still in. Completely back to normal after a night's sleep. I went through two runs of a half dozen treatments. My PSA came back down dramatically. Not to normal but much lower. So it does work on stage IV as well. Medicare paid for the administration costs but not for the chemicals. Recently my PSA has gone way up and my femur was taken over by cancer. After an operation to put a pin in the femur and radiation treatment my leg is getting back to normal. A few days ago I saw an oncologist who specializes in chemo. He was very honest. He recommended chemo but said that chemo only had a 20% chance of getting rid of the cancer. I told him about IPT. He had never heard of it and said it was not a recognized treatment. I said my holistic doctor was not a " one size fits all " alternative specialist but would not hesitate to recommend regular medical treatment, including regular chemo if indicated. He said in that case it would be ok to do IPT. He agreed it would be an easier path. As soon as I get out of the rehabilitation hospital I will immediately start another course of IPT. I am definitely in favor of IPT, particularly when I hear the horror stories of the side effects of regular chemo. I would definitely recommend IPT for anyone, particularly as the first step in treatment. It is definitely a smoother gradient, particularly for an older person. And it doesn't rule out regular treatment later if wanted. Phil ----- Original Message ----- From: Judy Silverman <maturelady1@...> >Read a lot about IPT - it does work a lot better than standard chemo. Cancer thrives on sugar - glucose level is lowered, cancer loses its permeability, then 10% of normal chemo is introduced into body with glucose and other things and cancer sucks just about all of it up because it needs the glucose to survive - and there are very few if any side effects because your good cells do not poisoned. It works best with stage I and II. --- Sharon Fan <shinyu_fan@...> wrote: > > Has anyone had any experience with Insulin > Potentiation Therapy (IPT)? > My mom is 77 years old and was diagnosed with stage > II breast cancer. I > thought this low-dose chemotherapy may be a better > option for her than > the traditional chemo. > > If anyone had any personal experience, or have any > advice, I'd really > appreciate if you don't mind sharing it with me. > Shinyu Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2003 Report Share Posted November 2, 2003 I did the IPT a year & a half ago so I don't recall exactly but I think it was twice a week. As I mentioned in my original posting chemo only has a 20% success rate so full cures are very unlikely. I see no reason why the IPT success rate would be any less than regular chemo. Phil ----- Original Message ----- From: Sharon Fan <shinyu_fan@...> Hi Phil, Thanks so much for sharing your experience. That is really helpful, and I hope you will recover very soon. How often did you get the IPT treatment? Once a week? Also, you mentioned that your PSA has gone up quite a lot, does this mean IPT is not that effective after all? Thanks again, Sharon --- Skytrekker <yh@...> wrote: > I've been through a course if IPT (Insulin Potentiation Therapy) at a > holistic medical clinic here in Clearwater FL so I can relate my > experiences. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2003 Report Share Posted November 2, 2003 I did the IPT a year & a half ago so I don't recall exactly but I think it was twice a week. As I mentioned in my original posting chemo only has a 20% success rate so full cures are very unlikely. I see no reason why the IPT success rate would be any less than regular chemo. Phil ----- Original Message ----- From: Sharon Fan <shinyu_fan@...> Hi Phil, Thanks so much for sharing your experience. That is really helpful, and I hope you will recover very soon. How often did you get the IPT treatment? Once a week? Also, you mentioned that your PSA has gone up quite a lot, does this mean IPT is not that effective after all? Thanks again, Sharon --- Skytrekker <yh@...> wrote: > I've been through a course if IPT (Insulin Potentiation Therapy) at a > holistic medical clinic here in Clearwater FL so I can relate my > experiences. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 15, 2010 Report Share Posted February 15, 2010 Has anyone had any experience with IPT? good or bad? I'd appreciate any and all feedback on this type of treatment. Thank You Nili Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 16, 2010 Report Share Posted February 16, 2010 " ngitig1 " <ngitig@...> wrote: > Has anyone had any experience with IPT? No personal experience, but I know tons about it. What would you like to know? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 10, 2010 Report Share Posted September 10, 2010 I looked into this. I'm guessing it would be considered an alternative therapy, and it is certainly controversial. Most of the scientific literature about this method is not in English, which didn't help me at all. I spoke with the medical director at a cancer clinic in Atlanta, which has an extensive alternative treatment program. They use this, but have treated less than 10 patients with CLL. Most of their cancer patients are colon and breast cancer. I didn't feel comfortable doing this without any confirmed proof that it works. That proof may exist, but I could not find it in English. The Atlanta clinic (immunterecovery.net) uses low doses of Fludarabine and Rituxan for the insulin potentiated therapy. My concern was that if it didn't work, I might lose my ability to respond to full dose Fludarabine. There are clinics in Mexico and other countries that also use this method. You might try researching those. If you speak other languages you'll have better luck than me in accessing clinical studies. Ron In a message dated 9/10/2010 6:47:35 A.M. Pacific Daylight Time, writes: anyone have investigated Insulin Potentialtion therapy for cll...or biotherapy/immunine therapy..i am trying to investigage less toxic, more effective chemotherapy, if there is such a thing. Quote Link to comment Share on other sites More sharing options...
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