Re: Reversatrol & liver cancer.

[Guest guest]

Is there any research done on the efffects (+ or-) of using reversatrol for a

liver cancer patient?

Neill

[Guest guest]

Deactivation of cultured human liver myofibroblasts by Trans-resveratrol, a

grapevine-derived polyphenol ;

" Liver myofibroblasts are major actors in the development of liver fibrosis and

cancer progression...We have shown that trans-resveratrol profoundly affects

myofibroblast phenotype. Trans-resveratrol induced morphological modifications.

It markedly reduced proliferation of myofibroblasts in a dose-dependent manner.

http://www3.interscience.wiley.com/journal/106596769/abstract?CRETRY=1 & SRETRY=0

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HERE A LINK TO MANY RESEARCHES ON CANCER + LIVER

http://scholar.google.com/scholar?q=resveratrol+liver & btnG=Search & hl=en & lr=

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Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from

Grapes

" Resveratrol, a phytoalexin found in grapes and other food products, was

purified and shown to have cancer chemopreventive activity in assays

representing three major stages of carcinogenesis. Resveratrol was found to act

as an antioxidant and antimutagen and to induce phase II drug-metabolizing

enzymes (anti-initiation activity); it mediated anti-inflammatory effects and

inhibited cyclooxygenase and hydroperoxidase functions (antipromotion activity);

and it induced human promyelocytic leukemia cell differentiation

(antiprogression activity). In addition, it inhibited the development of

preneoplastic lesions in carcinogen-treated mouse mammary glands in culture and

inhibited tumorigenesis in a mouse skin cancer model. These data suggest that

resveratrol, a common constituent of the human diet, merits investigation as a

potential cancer chemopreventive agent in humans "

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