Noscapine as an Apoptosis Inducer / Inviting our Resident Scholars to Comment

[Guest guest]

In delving into the pile of research I have been doing, I was amazed to hear

that Noscapine, a legally available prescription cough suppressant with a safe

profile, has been researched to induce apoptosis via the microtubule pathway and

to potentiate radiation treatments as well.

I would love to know what Vince, Leonard and our other resident brains make of

this.

<http://www.ncbi.nlm.nih.gov/pubmed/18338172?itool=EntrezSystem2.PEntrez.Pubmed.\

Pubmed_ResultsPanel.Pubmed_RVDocSum & ordinalpos=29>

( " CONCLUSION: Our studies suggest that potent antitumor activity of Nos against

NSCLC cells. Oral administration of Nos showed significant reduction in tumor

volume in human non-small cell lung tumor xenograft in nude mice in a dose

dependant manner. Thus, Nos is a promising novel chemotherapeutic agent for the

treatment of human lung cancer. " )

<http://www.ncbi.nlm.nih.gov/pubmed/18640497?itool=EntrezSystem2.PEntrez.Pubmed.\

Pubmed_ResultsPanel.Pubmed_RVDocSum & ordinalpos=25>

<http://www.ncbi.nlm.nih.gov/pubmed/19125622?itool=EntrezSystem2.PEntrez.Pubmed.\

Pubmed_ResultsPanel.Pubmed_RVDocSum & ordinalpos=19>

<http://www.caspases.org/showabstract.php?pmid=18640497>

<http://www.noscapine.org/>

CAUTION - HOWEVER, THERE ARE INDICATIONS IN THE LITERATURE THAT NOSCAPINE CAN

CREATE A DANGEROUS INTERACTION WITH COUMADIN SO OF COURSE CONSULT WITH A

PHYSICIAN AS ALWAYS