Re: Low Testosterone LH/Low Growth Hormone and now maybe high prolactin help????

[Guest guest]

Hi Chris

If the first MRI was not done right then yes you can have a pituitary problem.

Did they use high resolution doing without shooting you with die and with die.

chis_az <chis_az@...> wrote:

I have had low testosterone for a good few years now.

Originally I had boardline low testosterone levels of 10.2nmol/ and a

nomral LH level. I had a Insulin Tollerance Test four years ago as

well and that was perfectly normal and was 44 (UK reference) MU/L.

I also had an MRI which was normal, prolactin levels were also normal

and adrenal and thyroid hormones that were repeatedly very good/normal.

So boarderline low testosterone looked to be the only issue.

My health has gone dramatically downhill over the course of four years.

I had a new Insulin Tollerance Test a few months ago and it showed that

I now have low growth hormone with a UK level of 9mu/l (works out to

around 3 of the US range). So we had a before and after test and can

see that Growth Hormone has gone from 44mu/l to 9mu/l somehow in the

last four years.

I also came off testosterone for three months to see what my baseline

testosterone level was and it now showed a level of 5.6nmol/l and my LH

still normal. So my testosterone has gone from 10.6 to 5.6 and my

growth hormone from 44 to 9.

I has seemed that these values have plummeted in a way that has

mirrored my continuingly worse health.

A few months ago I started geting these sharp pains behind my left eye,

just imtermitently- not like a headache. They have continued every

week since, just now and again I get a sharp pain behind the eye.

My eyes have subsequently started to swell up and my left eye in

particular has swollen quite badley to the point where the eyelid

cannot be seen and it is affecting my vision a little.

Three weeks ago I had a prolactin test and it came back a little bit

high. 378 Uk reference range (0-350). I had another test a week ago

and that has come back also a little high 387 (0-350).

What are the odds that the dropping of the baseline testosterone and

growth hormone levels and the now growth hormone deficiency (doctors

are trying to get me on GH therapy) is down to a prolactinoma or

pituitary tumor?

I thought that prolactin was usually through the roof before it ever

caused significant issues?

Is this just a red herring or is this the cause of everything?

could a problem have been missed on the original MRI?

Obviously no one can say, but I would be very interested to hear

peoples thoughts on this?

What does that level come to on the US range?

Would that prolactin level be an issue at all?

Co-Moderator " Don't believe anything you hear and only half of what you see. "

Phil

---------------------------------

Never miss a thing. Make your homepage.

[Guest guest]

> I have had low testosterone for a good few years now.

>

> Originally I had boardline low testosterone levels of 10.2nmol/ and a

> nomral LH level. I had a Insulin Tollerance Test four years ago as

> well and that was perfectly normal and was 44 (UK reference) MU/L.

>

> I also had an MRI which was normal, prolactin levels were also normal

> and adrenal and thyroid hormones that were repeatedly very good/normal.

>

> So boarderline low testosterone looked to be the only issue.

>

> My health has gone dramatically downhill over the course of four years.

>

> I had a new Insulin Tollerance Test a few months ago and it showed that

> I now have low growth hormone with a UK level of 9mu/l (works out to

> around 3 of the US range). So we had a before and after test and can

> see that Growth Hormone has gone from 44mu/l to 9mu/l somehow in the

> last four years.

>

> I also came off testosterone for three months to see what my baseline

> testosterone level was and it now showed a level of 5.6nmol/l and my LH

> still normal. So my testosterone has gone from 10.6 to 5.6 and my

> growth hormone from 44 to 9.

>

> I has seemed that these values have plummeted in a way that has

> mirrored my continuingly worse health.

>

> A few months ago I started geting these sharp pains behind my left eye,

> just imtermitently- not like a headache. They have continued every

> week since, just now and again I get a sharp pain behind the eye.

>

> My eyes have subsequently started to swell up and my left eye in

> particular has swollen quite badley to the point where the eyelid

> cannot be seen and it is affecting my vision a little.

>

> Three weeks ago I had a prolactin test and it came back a little bit

> high. 378 Uk reference range (0-350). I had another test a week ago

> and that has come back also a little high 387 (0-350).

>

> What are the odds that the dropping of the baseline testosterone and

> growth hormone levels and the now growth hormone deficiency (doctors

> are trying to get me on GH therapy) is down to a prolactinoma or

> pituitary tumor?

>

> I thought that prolactin was usually through the roof before it ever

> caused significant issues?

>

> Is this just a red herring or is this the cause of everything?

>

> could a problem have been missed on the original MRI?

>

> Obviously no one can say, but I would be very interested to hear

> peoples thoughts on this?

>

> What does that level come to on the US range?

>

> Would that prolactin level be an issue at all?

>

>

>

>

>

>

> Co-Moderator " Don't believe anything you hear and only half of what

you see. "

> Phil

>

> ---------------------------------

> Never miss a thing. Make your homepage.

>

>

[Guest guest]

Thanks for the replies Jim and Phil.

The scan I had four years ago was of the pituitary and at that time

the testosterone was boarderline low and I had good GH levels and

back then my prolactin was around 200 on the UK range and within

range.

Now I have testosterone that is very low if off treatment at baseline

and diagnosed GH deficiency.

I guess I am wondering could a prolactin level that is only a little

above normal be a pituitary tumor even if it has been this way on two

tests? I was thinking it was unlikely but???

I guess it might be possible that there was no problem on an MRI four

years ago and there would be now?

Ovbiously the prolactin is not through the roof high and not even

that much above the top of the range.

Anyone know what my levels would be on the US range?

P.S

I think I was injected with something on the MRI scan- once.

> > I have had low testosterone for a good few years now.

> >

> > Originally I had boardline low testosterone levels of 10.2nmol/

and a

> > nomral LH level. I had a Insulin Tollerance Test four years ago

as

> > well and that was perfectly normal and was 44 (UK reference) MU/L.

> >

> > I also had an MRI which was normal, prolactin levels were also

normal

> > and adrenal and thyroid hormones that were repeatedly very

good/normal.

> >

> > So boarderline low testosterone looked to be the only issue.

> >

> > My health has gone dramatically downhill over the course of four

years.

> >

> > I had a new Insulin Tollerance Test a few months ago and it

showed that

> > I now have low growth hormone with a UK level of 9mu/l (works out

to

> > around 3 of the US range). So we had a before and after test and

can

> > see that Growth Hormone has gone from 44mu/l to 9mu/l somehow in

the

> > last four years.

> >

> > I also came off testosterone for three months to see what my

baseline

> > testosterone level was and it now showed a level of 5.6nmol/l and

my LH

> > still normal. So my testosterone has gone from 10.6 to 5.6 and my

> > growth hormone from 44 to 9.

> >

> > I has seemed that these values have plummeted in a way that has

> > mirrored my continuingly worse health.

> >

> > A few months ago I started geting these sharp pains behind my

left eye,

> > just imtermitently- not like a headache. They have continued

every

> > week since, just now and again I get a sharp pain behind the eye.

> >

> > My eyes have subsequently started to swell up and my left eye in

> > particular has swollen quite badley to the point where the eyelid

> > cannot be seen and it is affecting my vision a little.

> >

> > Three weeks ago I had a prolactin test and it came back a little

bit

> > high. 378 Uk reference range (0-350). I had another test a week

ago

> > and that has come back also a little high 387 (0-350).

> >

> > What are the odds that the dropping of the baseline testosterone

and

> > growth hormone levels and the now growth hormone deficiency

(doctors

> > are trying to get me on GH therapy) is down to a prolactinoma or

> > pituitary tumor?

> >

> > I thought that prolactin was usually through the roof before it

ever

> > caused significant issues?

> >

> > Is this just a red herring or is this the cause of everything?

> >

> > could a problem have been missed on the original MRI?

> >

> > Obviously no one can say, but I would be very interested to hear

> > peoples thoughts on this?

> >

> > What does that level come to on the US range?

> >

> > Would that prolactin level be an issue at all?

> >

> >

> >

> >

> >

> >

> > Co-Moderator " Don't believe anything you hear and only half of

what

> you see. "

> > Phil

> >

> > ---------------------------------

> > Never miss a thing. Make your homepage.

> >

> >

[Guest guest]

we have a new web site up for Dr. I am a mod and Hardasnails maybe

you can get some good info from the guys at this site.

Come and join everyone is welcome.

http://74.54.133.233/forum/forumdisplay.php?s= & daysprune= & f=2

chis_az <chis_az@...> wrote:

Thanks for the replies Jim and Phil.

The scan I had four years ago was of the pituitary and at that time

the testosterone was boarderline low and I had good GH levels and

back then my prolactin was around 200 on the UK range and within

range.

Now I have testosterone that is very low if off treatment at baseline

and diagnosed GH deficiency.

I guess I am wondering could a prolactin level that is only a little

above normal be a pituitary tumor even if it has been this way on two

tests? I was thinking it was unlikely but???

I guess it might be possible that there was no problem on an MRI four

years ago and there would be now?

Ovbiously the prolactin is not through the roof high and not even

that much above the top of the range.

Anyone know what my levels would be on the US range?

P.S

I think I was injected with something on the MRI scan- once.

> > I have had low testosterone for a good few years now.

> >

> > Originally I had boardline low testosterone levels of 10.2nmol/

and a

> > nomral LH level. I had a Insulin Tollerance Test four years ago

as

> > well and that was perfectly normal and was 44 (UK reference) MU/L.

> >

> > I also had an MRI which was normal, prolactin levels were also

normal

> > and adrenal and thyroid hormones that were repeatedly very

good/normal.

> >

> > So boarderline low testosterone looked to be the only issue.

> >

> > My health has gone dramatically downhill over the course of four

years.

> >

> > I had a new Insulin Tollerance Test a few months ago and it

showed that

> > I now have low growth hormone with a UK level of 9mu/l (works out

to

> > around 3 of the US range). So we had a before and after test and

can

> > see that Growth Hormone has gone from 44mu/l to 9mu/l somehow in

the

> > last four years.

> >

> > I also came off testosterone for three months to see what my

baseline

> > testosterone level was and it now showed a level of 5.6nmol/l and

my LH

> > still normal. So my testosterone has gone from 10.6 to 5.6 and my

> > growth hormone from 44 to 9.

> >

> > I has seemed that these values have plummeted in a way that has

> > mirrored my continuingly worse health.

> >

> > A few months ago I started geting these sharp pains behind my

left eye,

> > just imtermitently- not like a headache. They have continued

every

> > week since, just now and again I get a sharp pain behind the eye.

> >

> > My eyes have subsequently started to swell up and my left eye in

> > particular has swollen quite badley to the point where the eyelid

> > cannot be seen and it is affecting my vision a little.

> >

> > Three weeks ago I had a prolactin test and it came back a little

bit

> > high. 378 Uk reference range (0-350). I had another test a week

ago

> > and that has come back also a little high 387 (0-350).

> >

> > What are the odds that the dropping of the baseline testosterone

and

> > growth hormone levels and the now growth hormone deficiency

(doctors

> > are trying to get me on GH therapy) is down to a prolactinoma or

> > pituitary tumor?

> >

> > I thought that prolactin was usually through the roof before it

ever

> > caused significant issues?

> >

> > Is this just a red herring or is this the cause of everything?

> >

> > could a problem have been missed on the original MRI?

> >

> > Obviously no one can say, but I would be very interested to hear

> > peoples thoughts on this?

> >

> > What does that level come to on the US range?

> >

> > Would that prolactin level be an issue at all?

> >

> >

> >

> >

> >

> >

> > Co-Moderator " Don't believe anything you hear and only half of

what

> you see. "

> > Phil

> >

> > ---------------------------------

> > Never miss a thing. Make your homepage.

> >

> >

[Guest guest]

>

> Three weeks ago I had a prolactin test and it came back a little bit

> high. 378 Uk reference range (0-350). I had another test a week

ago

> and that has come back also a little high 387 (0-350).

>

>

It looks like the prolactin test numbers are in

millimoles per litre (mmol/L) though my textbook says

the SI units for prolactin are nanomoles per litre (nmol/L).

The American units are ng/mL. The range is 0 to 15 ng/mL.

The conversion factor from ng/mL to nmol/L is 0.045 hence,

the conversion factor from ng/mL to mmol/L is 45.

So values below 675 would be considered in range

according to this book. The book is 14 years old.

So, it is also possible the test itself has changed

such the test give different number???

Anyway try to include the number labels/factor labels

with the numbers.

Dwight

[Guest guest]

I appreciate the attempt to convert the reference ranges

Dwight...cheers

The reference I have been given is definitely in miu/L though and not

nmol/l.

I had a prolactin level of around 140miu/l two years ago then it went

to 250miu/l, then to 378miu/l and now to 387miu/l and my my reference

range is given as 0-350.

I have not been able to convert this range to the US or SI levels

despite trying to search the web in order to do so...so I guess I

just wont get to know what this would represent in US terms.

Thanks for trying again though Dwight

>

>

> >

> > Three weeks ago I had a prolactin test and it came back a little

bit

> > high. 378 Uk reference range (0-350). I had another test a week

> ago

> > and that has come back also a little high 387 (0-350).

> >

> >

>

> It looks like the prolactin test numbers are in

> millimoles per litre (mmol/L) though my textbook says

> the SI units for prolactin are nanomoles per litre (nmol/L).

>

> The American units are ng/mL. The range is 0 to 15 ng/mL.

> The conversion factor from ng/mL to nmol/L is 0.045 hence,

> the conversion factor from ng/mL to mmol/L is 45.

> So values below 675 would be considered in range

> according to this book. The book is 14 years old.

> So, it is also possible the test itself has changed

> such the test give different number???

>

> Anyway try to include the number labels/factor labels

> with the numbers.

>

> Dwight

>

[Guest guest]

On Mon, 07 Jan 2008 20:46:12 -0000, you wrote:

>I appreciate the attempt to convert the reference ranges

>Dwight...cheers

>

>The reference I have been given is definitely in miu/L though and not

>nmol/l.

>

>I had a prolactin level of around 140miu/l two years ago then it went

>to 250miu/l, then to 378miu/l and now to 387miu/l and my my reference

>range is given as 0-350.

>

>I have not been able to convert this range to the US or SI levels

>despite trying to search the web in order to do so...so I guess I

>just wont get to know what this would represent in US terms.

http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B7GVY-4MY6NG7-1 & _user=1\

0 & _rdoc=1 & _fmt= & _orig=search & _sort=d & view=c & _acct=C000050221 & _version=1 & _urlVers\

ion=0 & _userid=10 & md5=6a2373c63e36e492913ceca210741df7

" The following conversion factor was given: 1 µg=26 mIU S-prolactin. "

http://www.clinchem.org/cgi/content/full/49/9/1504/T1

2 To convert prolactin mIU/L to µg/L, divide by 36.

http://www.vin.com/scripts/labquest/converthtml.pl

Prolactin ng/ml 1 µg/L

>

>Thanks for trying again though Dwight

[Guest guest]

On Mon, 07 Jan 2008 20:46:12 -0000, you wrote:

>I appreciate the attempt to convert the reference ranges

>Dwight...cheers

>

>The reference I have been given is definitely in miu/L though and not

>nmol/l.

>

>I had a prolactin level of around 140miu/l two years ago then it went

>to 250miu/l, then to 378miu/l and now to 387miu/l and my my reference

>range is given as 0-350.

>

>I have not been able to convert this range to the US or SI levels

>despite trying to search the web in order to do so...so I guess I

>just wont get to know what this would represent in US terms.

>

>Thanks for trying again though Dwight

This article with the conversion in a footnote may interest you also:

http://www.clinchem.org/cgi/reprint/49/9/1504.pdf

Frequent Misdiagnosis and Mismanagement of

Hyperprolactinemic Patients before the

Introduction of Macroprolactin Screening:

Application of a New Strict Laboratory Definition

of Macroprolactinemia

[Guest guest]

Thanks for all the info.

At the moment I am a little confused to say the least.

I mean I have a pain that eminates from behind one eye exactly where

the pituitary is. The skin surrounding that eye has swollen and my

vision is a little odd. I have prolactin that has increased and gone

above the reference range and has continued to increase little by

little for 2 years...but it is not high enough to shout prolactinoma.

All the while my health has been deteriorating greatly and my

baseline testosterone has gone from 283ng/ml to 161ng/dl and my

Growth Hormone has gone from being 44 and a very health level on the

UK reference range to 0.5-9 and I now have Growth Hormone Deficiency.

Plummiting health....cause unknown- effects very low testosterone and

GH levels- hypopituitary and osteoporosis. Two years ago bone

density was minus 1.5. Now it is minus 2.8.

I have been on all forms of TRT without success at all doses with or

without arimidex at all doses.

Something is causing all this....whatever it is seems impossible to

find.

I have gone from being health and having no health issue four years

ago to severe osteoporosis of the spine- low testosterone and low

growth hormone....now these headaches/eye problem that I have had for

months......VERY odd.

>

> >I appreciate the attempt to convert the reference ranges

> >Dwight...cheers

> >

> >The reference I have been given is definitely in miu/L though and

not

> >nmol/l.

> >

> >I had a prolactin level of around 140miu/l two years ago then it

went

> >to 250miu/l, then to 378miu/l and now to 387miu/l and my my

reference

> >range is given as 0-350.

> >

> >I have not been able to convert this range to the US or SI levels

> >despite trying to search the web in order to do so...so I guess I

> >just wont get to know what this would represent in US terms.

> >

> >Thanks for trying again though Dwight

>

>

> This article with the conversion in a footnote may interest you

also:

> http://www.clinchem.org/cgi/reprint/49/9/1504.pdf

>

> Frequent Misdiagnosis and Mismanagement of

> Hyperprolactinemic Patients before the

> Introduction of Macroprolactin Screening:

> Application of a New Strict Laboratory Definition

> of Macroprolactinemia

>

[Guest guest]

http://www.unc.edu/~rowlett/units/scales/clinical_data.html

http://www.globalrph.com/conv_si.htm#Epinephrine

Try both of these and search for the Prolactin

conversion.

I converted mine from one of these.

--- chis_az <chis_az@...> wrote:

> I appreciate the attempt to convert the reference

> ranges

> Dwight...cheers

>

> The reference I have been given is definitely in

> miu/L though and not

> nmol/l.

>

> I had a prolactin level of around 140miu/l two years

> ago then it went

> to 250miu/l, then to 378miu/l and now to 387miu/l

> and my my reference

> range is given as 0-350.

>

> I have not been able to convert this range to the US

> or SI levels

> despite trying to search the web in order to do

> so...so I guess I

> just wont get to know what this would represent in

> US terms.

>

> Thanks for trying again though Dwight

>

>

>

>

>

> >

> >

> > >

> > > Three weeks ago I had a prolactin test and it

> came back a little

> bit

> > > high. 378 Uk reference range (0-350). I had

> another test a week

> > ago

> > > and that has come back also a little high 387

> (0-350).

> > >

> > >

> >

> > It looks like the prolactin test numbers are in

> > millimoles per litre (mmol/L) though my textbook

> says

> > the SI units for prolactin are nanomoles per litre

> (nmol/L).

> >

> > The American units are ng/mL. The range is 0 to 15

> ng/mL.

> > The conversion factor from ng/mL to nmol/L is

> 0.045 hence,

> > the conversion factor from ng/mL to mmol/L is 45.

> > So values below 675 would be considered in range

> > according to this book. The book is 14 years old.

> > So, it is also possible the test itself has

> changed

> > such the test give different number???

> >

> > Anyway try to include the number labels/factor

> labels

> > with the numbers.

> >

> > Dwight

> >

>

>

>

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