Guest guest Posted July 24, 2009 Report Share Posted July 24, 2009 Hi, If it is typo, the Doc gave you Arimidex which is meant to lower you E2 . I am not exactly sure for the reason that, your doc prescribed it, with the Claim that it will increase your T - but, as Phil ( The moderator of this group ) had informed in my earlier query regarding low T , he had said this : " . If your E2 is high it takes away from the good the testim you were on would do. High e2 to the brain looks like Testosterone because E2 is made from T so when E2 is high it thinks it's T and slows down your LH and FSH this is the message from your pituitary to your testis to make more T. " Now, you are not yet using Testim, but the Doc's rational may be the same as Phil had mentioned to me earlier as above i.e. Arimidex reduces E2 > Brain senses it as the reduction in T > which in turn causes T to go high naturally . I honestly believe, Phil is ' The Man ' to answer this more decisively . I have read across the net on several forum ( and have experienced myself when I blindly trusted my Endo and was stupid enough to start the Testim without any of my own homework !! ) that, once you start taking any pills, gels or injection which meant to increase your T, you have to be very very careful ' hows, whys and whats ' of it's effects on your mind and body. I ended up in Gynacomastia even after 2 months of Gel for T . So, the only way to know is to try and be very very 'watchful'. I won't presume any TRT related stuff to be safe ! Thanks, - RP > > > > > > > > >Here's an update regarding my situation > > > > > > > > > >I had the MRI on my Pituitary on Monday. I got a telephone call today with the results. It turns out that my Pituitary is normal, they found nothing wrong with it. The Dr's assistant told me over the telephone because my T levels low-normal the Endo wants to hold off on Testosterone Replacement and wants me to get another Blood Test in 3 months. I like this course of action because if I was offered it anyway I wanted to take time to see if Lifestyle changes could have some kind of impact because offer the past few months I have been very stressed and have barely gotten any sleep, went to sleep at different times because of this. I have been majorly depressed over it. > > > > > > > > > >So I don't know what I'm going to do now that I got my results; there is nothing wrong with my pituitary, yet my T Level's are still low. I have an appointment next week with a Urologist for a different issue and will probably bring this to his attention, see what he has to say about it. > > > > > > > > > > > > Have they run a cortisol test? With high stress it climbs and can > > > > cause low T. But if you're cortisol levels are normal and T is not up, > > > > I'd get started on T sooner than later. At least for me the loss of > > > > energy, ambition and mental fog were too much to live with and keep a > > > > job, etc. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2009 Report Share Posted July 24, 2009 Amrimidex inhibits the conversion of T to E2 via aromatization. It does indeed increase your T levels, since the T that would have been converted to E2, remains T. > > Hi, > > If it is typo, the Doc gave you Arimidex which is meant to lower you E2 . I am not exactly sure for the reason that, your doc prescribed it, with the Claim that it will increase your T Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2009 Report Share Posted July 24, 2009 On Fri, 24 Jul 2009 18:22:47 -0000, you wrote: >It does indeed increase your T levels, since the T that would have been converted to E2, remains T. In addition to that E2 signals the hypothalamus and pituitary to make less GNRH and FSH. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2009 Report Share Posted July 25, 2009 When you say E2 signals the hypo & pit. to make less FSH is that when the E2 levels are high? Would a decrease in the E2 level make FSH go up? My E2 is a little bit high as you pointed out and my FSH level actually happens to be low. The two times I got it tested it was around 1. Both tests were done in the afternoon and not early in the morning though so I don't know how much of an effect this had but clearly they aren't where they should be. > > >It does indeed increase your T levels, since the T that would have been converted to E2, remains T. > > > In addition to that E2 signals the hypothalamus and pituitary to make > less GNRH and FSH. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2009 Report Share Posted July 25, 2009 Thanks for your message RP. No, I am not on any kind of testosterone therapy at the moment. They wanted to put me on it initially after my first total t test and LH test months ago came back below normal but I told them it would be better to do some investigating first as it was a bit premature. While low those numbers were from a test done in the afternoon and I learned you are supposed to get tests for these things in the morning. i had it redone once after 9 am and total test was over 400 and lh close to 4. while not super spectacular numbers i was told it would be better to try other things to see if they could help before administring testosterone. since then i have found out my estradiol level is on the high side at 41 and i have been wondering if that is the reason why my test, lh and fsh have been coming in so low. > > > > > > > > > > >Here's an update regarding my situation > > > > > > > > > > > >I had the MRI on my Pituitary on Monday. I got a telephone call today with the results. It turns out that my Pituitary is normal, they found nothing wrong with it. The Dr's assistant told me over the telephone because my T levels low-normal the Endo wants to hold off on Testosterone Replacement and wants me to get another Blood Test in 3 months. I like this course of action because if I was offered it anyway I wanted to take time to see if Lifestyle changes could have some kind of impact because offer the past few months I have been very stressed and have barely gotten any sleep, went to sleep at different times because of this. I have been majorly depressed over it. > > > > > > > > > > > >So I don't know what I'm going to do now that I got my results; there is nothing wrong with my pituitary, yet my T Level's are still low. I have an appointment next week with a Urologist for a different issue and will probably bring this to his attention, see what he has to say about it. > > > > > > > > > > > > > > > Have they run a cortisol test? With high stress it climbs and can > > > > > cause low T. But if you're cortisol levels are normal and T is not up, > > > > > I'd get started on T sooner than later. At least for me the loss of > > > > > energy, ambition and mental fog were too much to live with and keep a > > > > > job, etc. > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2009 Report Share Posted July 25, 2009 Yes your brain sees Estradiol as if it's Testosterone so when your Estradiol is high it thinks it's testosterone and slows down sending the LH and FSH messages to your testis to make more testosterone. You see Estradiol is made from Testosterone in men and the brain can't tell the difference try getting the Estradiol down and see if your levels come back up if they don't and your LH and FSH are still low then you need to have an MRI done on your Pituitary to rule out a tumor this is rage to be cancer but is called Secondary Hypogonadism. Co-Moderator Phil > From: bsprulesall <bsprulesall@...> > Subject: Re: Help! I need advice. Low testosterone w/ lab results for refe > > Date: Saturday, July 25, 2009, 4:04 PM > When you say E2 signals the hypo > & pit. to make less FSH is that when the E2 levels are > high? Would a decrease in the E2 level make FSH go > up? My E2 is a little bit high as you pointed out and > my FSH level actually happens to be low. The two times > I got it tested it was around 1. Both tests were done > in the afternoon and not early in the morning though so I > don't know how much of an effect this had but clearly they > aren't where they should be. > > > > > > >It does indeed increase your T levels, since the T > that would have been converted to E2, remains T. > > > > > > In addition to that E2 signals the hypothalamus and > pituitary to make > > less GNRH and FSH. > > > > > > > ------------------------------------ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 25, 2009 Report Share Posted July 25, 2009 Yes dropping E2 could generate an increase in FSH according to these studies: http://www.ncbi.nlm.nih.gov/pubmed/11231978?ordinalpos=3 & itool=EntrezSystem2.PEn\ trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum http://www.ncbi.nlm.nih.gov/pubmed/10999781?ordinalpos=4 & itool=EntrezSystem2.PEn\ trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum http://www.ncbi.nlm.nih.gov/pubmed/15483079?ordinalpos=1 & itool=EntrezSystem2.PEn\ trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum http://www.ncbi.nlm.nih.gov/pubmed/11397860?ordinalpos=2 & itool=EntrezSystem2.PEn\ trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum http://www.ncbi.nlm.nih.gov/pubmed/10902781?ordinalpos=5 & itool=EntrezSystem2.PEn\ trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum On Sat, 25 Jul 2009 20:04:33 -0000, you wrote: >When you say E2 signals the hypo & pit. to make less FSH is that when the E2 levels are high? Would a decrease in the E2 level make FSH go up? My E2 is a little bit high as you pointed out and my FSH level actually happens to be low. The two times I got it tested it was around 1. Both tests were done in the afternoon and not early in the morning though so I don't know how much of an effect this had but clearly they aren't where they should be. > > >> >> >It does indeed increase your T levels, since the T that would have been converted to E2, remains T. >> >> >> In addition to that E2 signals the hypothalamus and pituitary to make >> less GNRH and FSH. >> > Quote Link to comment Share on other sites More sharing options...
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