Re: Posting on behalf of a friend who has just started HRT

[Guest guest]

I've found that spreading the dose over 2 shots helps keep

E2 levels down and keeps everything on a more even keel.

Danazol works primarily by telling the pituitary to ignore

the GnRH pulses from the hypothalamus which lowers

endogenous LH & FSH. It is used in this way to treat

gynecomastia in teens. Lowering LH & FSH would suppress

any gonadal involvement in elevating E2, but there are

still 2 other sources of E2. One is aromatization of T, which

can easily be modulated by the use of arimidex or letrazole,

and the other significant source is the adrenal system. If

the body has a high cortisol burden, the adrenals will put

out more E2 to help store energy and serve as a nerve

protectant. Off hand, the only thing I can think of to modulate

that is to work on lessening the bodies stress response by

environmental change, or mood stabilizers.

Wups, I better put the obligitory disclaimer in here...

This is not medical advice. Before attempting any activities

mentioned herein, please seek out proper medical supervision.

Good luck and good health!

-Mike

>

> Hey guys, I was hoping that I could ask some advice on behalf of a

> friend (and I am not just trying to pretend it isn't me). He is a man

> like me and has a history of really bad reactions to elevated

> estrogen. He started testosterone injection 3 months ago and has been

> complaining of problems for the last 2 months. I believe it is his

> estrogen levels but I think it might help if I get some feedback from

> the community. So everyone shout out if you want.

>

> He has had some success using danzanol in the past but after 6 months

> side effects forced him off the drug. He was on 70mg T-cyp a week and

> his free T came back at 85pmol and the second test came back at

> 89pmol. His doctor lowered the dose to 60mg but he is worried that he

> won't have results with such a small dose. I tried to reassure him

> that if his free T is in that range then he should be fine on a

> testosterone level.

>

> His general doctor hasn't tested his E2 properly and he hasn't been

> able to give me a number; only saying that they doctor said his E2 was

> slightly elevated from last time but not saying what the actual number

> was. He is complaining of wild swings. Initially stable cycle of

> feeling well for the first 3 days and then having problems until the

> next shot (i.e. anxiety, mood fluctuation, sleeping disorders etc) The

> cycle of swings has changed recently and is no longer predictable. He

> had some effects during the first month on the shots but since then is

> complaining that he isn't having any improvement and at times feels he

> is regressing.

>

> My inclination is to say that the shots on a weekly cycle are pumping

> too much testosterone in at any given time and causing these swings

> along with elevated E2. I have advised that he should obtain his

> actual levels but right now that isn't going to happen. I have further

> advised that he should consider a trial of injecting on a 3-4 day

> cycle like I believe Phil is doing with half the dose and see if that

> resolves the issue. However he isn't prepared to accept my word on

> this matter. I would like to recommend this before suggesting an AI

> for a number of reasons.

>

> For the sake of this discussion lets assume he is primary. He is a

> member of this site and lurking so please be respectful and feel free

> to direct your response to me or him. He will read your responses and

> hopefully if he hears people wanting to help him, he can chime in with

> his own experience in his own words. This guy is new to HRT and really

> needs to feel supported right now. I know we all have had times when

> our hormone levels were off and it felt like we were alone in dealing

> with our issues. Lets show him that he isn't alone. Anyone who has

> dealt with only needing a small amounts of T to maintain serum levels

> would also be helpful.

>

> Phil, if you want to wade in with your opinion that would be really

> appreciated, I know your advice made a real difference for me.

> Especially helpful was your approach to finding the best treatment for

> the person instead of working off a preset formula. If you could give

> your opinion on the term " average dose " (i.e. 100mg a week) and if

> there is any difference between using 100mg/ml or 200mg/ml T-cyp

> besides size of injection. I don't think there is but I would like

> someone else's opinion.

>

> trannyboy

>

[Guest guest]

I don't know what this Dr. is giving him danzanol for I can't see anything a men

can use this for.

danzanol:

Male hormone used in the hormonal treatment of endometriosis in women by

suppressing the menstrual cycle for 6 to 9 months.

Doing 70mgs of T-cyp and having levels of 85pmol need to know the range can't

convert to nmol/L

He only need to get his Testosterone Total and Free into the upper 1/3 of his

labs range and to keep his E2 Estradiol down between 10 to 30 better at 20. I

feel he is feeling this way because his E2 is going to high. He would not need

to go to shots every 3 days or even 2x's a week if he took something to keep his

E2 levels down. If his Dr. will not give him Arimidex the have him order some

Indolplex/DIM take on tablet at dinner time and when his night time and moring

wood starts up his levels are good.

Keep taking this but if wood stops he is going to low so stop taking it until

wood comes back that day go back on it but cut the tablet in half.

This is the brand I know works there is a lot of diff. brands out there some

don't work.

http://www.ritecare.com/prodsheets/PHY-15336.html

I your shooting T that comes in a vile that is 200mgs/ml as to 100mgs/ml the

diff. is you only need .5mls to do a 100mgs shot of the 200mgs/ml vile.

Co-Moderator

Phil

> From: trannyboy84 <trannyboy@...>

> Subject: Posting on behalf of a friend who has just started HRT

>

> Date: Saturday, September 27, 2008, 5:41 AM

> Hey guys, I was hoping that I could ask some advice on

> behalf of a

> friend (and I am not just trying to pretend it isn't

> me). He is a man

> like me and has a history of really bad reactions to

> elevated

> estrogen. He started testosterone injection 3 months ago

> and has been

> complaining of problems for the last 2 months. I believe it

> is his

> estrogen levels but I think it might help if I get some

> feedback from

> the community. So everyone shout out if you want.

>

> He has had some success using danzanol in the past but

> after 6 months

> side effects forced him off the drug. He was on 70mg T-cyp

> a week and

> his free T came back at 85pmol and the second test came

> back at

> 89pmol. His doctor lowered the dose to 60mg but he is

> worried that he

> won't have results with such a small dose. I tried to

> reassure him

> that if his free T is in that range then he should be fine

> on a

> testosterone level.

>

> His general doctor hasn't tested his E2 properly and he

> hasn't been

> able to give me a number; only saying that they doctor said

> his E2 was

> slightly elevated from last time but not saying what the

> actual number

> was. He is complaining of wild swings. Initially stable

> cycle of

> feeling well for the first 3 days and then having problems

> until the

> next shot (i.e. anxiety, mood fluctuation, sleeping

> disorders etc) The

> cycle of swings has changed recently and is no longer

> predictable. He

> had some effects during the first month on the shots but

> since then is

> complaining that he isn't having any improvement and at

> times feels he

> is regressing.

>

> My inclination is to say that the shots on a weekly cycle

> are pumping

> too much testosterone in at any given time and causing

> these swings

> along with elevated E2. I have advised that he should

> obtain his

> actual levels but right now that isn't going to happen.

> I have further

> advised that he should consider a trial of injecting on a

> 3-4 day

> cycle like I believe Phil is doing with half the dose and

> see if that

> resolves the issue. However he isn't prepared to accept

> my word on

> this matter. I would like to recommend this before

> suggesting an AI

> for a number of reasons.

>

> For the sake of this discussion lets assume he is primary.

> He is a

> member of this site and lurking so please be respectful and

> feel free

> to direct your response to me or him. He will read your

> responses and

> hopefully if he hears people wanting to help him, he can

> chime in with

> his own experience in his own words. This guy is new to HRT

> and really

> needs to feel supported right now. I know we all have had

> times when

> our hormone levels were off and it felt like we were alone

> in dealing

> with our issues. Lets show him that he isn't alone.

> Anyone who has

> dealt with only needing a small amounts of T to maintain

> serum levels

> would also be helpful.

>

> Phil, if you want to wade in with your opinion that would

> be really

> appreciated, I know your advice made a real difference for

> me.

> Especially helpful was your approach to finding the best

> treatment for

> the person instead of working off a preset formula. If you

> could give

> your opinion on the term " average dose " (i.e.

> 100mg a week) and if

> there is any difference between using 100mg/ml or 200mg/ml

> T-cyp

> besides size of injection. I don't think there is but I

> would like

> someone else's opinion.

>

> trannyboy

>

>

> ------------------------------------

>

>