Info on Ovidrel

[Guest guest]

I found this on the web - it implys that those of us with ovidrel for HCG - the

0.5 cc syringe with 250 micrograms is equivalent to 6500 iu of the urine based

HCG. So if you dilute the syringe with 10 cc of water, this is only 650 iu per

cc or mil.

 

Arkansas

 

From: <androlog@...>

Date: Wed Sep 24 2008 - 07:00:12 CDT

Androlog Mail

Colleagues

A number of my severely hypogonadal male patients are having trouble finding

HCG (profasi, pregnyl) in the local pharmacies in my area (Indiana) even

pharmacies that cater to the IVF trade. They are told it is on 'national

backorder' or otherwise in short supply. An alternative is Ovidrel a recombinant

HCG product made by Serono. The original urinary HCG comes in international

units and Ovidrel is dosed in micrograms. I am told by the Serono rep that the

250 mcg Ovidrel pen (0.5cc) is equivalent to 6500 IU of urinary HCG. Given this

conversion factor, 50mcg of Ovidrel is roughly equal to 1500 IU urinary HCG and

therefore many of my patient will be using only about 0.1cc of the Ovidrel. I

plan to have my patients inject the Ovidrel pen into an empty sterile multi dose

vial and then redraw the amount needed out of this vial with a tuberculin

syringe for their injection.

My questions are

1. For those that have converted men from urinary HCG to Ovidrel is the

conversion factor above accurate and have they found the two products

biologically equivalent in this clinical setting?

2. Any better ideas for patients on how to use small quantities of the

ovidrel given the limitation of the 0.5cc/250mcg pens.

3. Has anyone studied or tried Luveris, recombinant luteinizing hormone

made by Serono, for severely hypogonadal men instead of an HCG product?

thanks for your help

T , MD

sthompson@...

From: rmpalp <motor815@...>

Subject: Re: Bacteriostatic Water

Date: Tuesday, December 2, 2008, 9:07 PM

I actually mix mine with 20 ml Bac Water. That way, with a 5000iu vial

of HCG, I get the dose I want of 250iu per 1cc injection. I haven't

found anything less than 30 ml Bac Water vials, though. I just draw

off 10 ml to start off with. I got mine from:

http://www.cheapvit amins.com/ Product/Bacterio static-Water- 30-ml.aspx

>

> Those of you that mix your HCG and have to have a 10 ml vial of

bacteriostatic water - where do you get it?

>

> Thanks Arkansas

>

[Guest guest]

I just started using Ovidrel since I'm having trouble finding Novarel. I mixed

the Ovidrel with 5ml of sterile water as instructed here and by my physician and

have now had two injections of .5 cc/ml each and noticed that this stuff burns a

lot going in. It really took me by surprise. I guess I was expecting it to be

comparable to the Novarel that I barely felt at all.

I can certainly deal with the different, yet annoying sensation, but I'm curious

if anyone else has experienced this. The difference, for me at least, is like

night and day.