Guest guest Posted February 1, 2007 Report Share Posted February 1, 2007 Nebido seems to be a favorite with the health care system in the UK. Some folks say it works well for them. There are lots who complain though that the mix results in uneven levels over the long time it is given for. It's a sort of cocktail with some short term release T formulation, a mid term and long term component. Evidently in lots of people these different formulations don't " burn " evenly and they end up with low levels along the way. Most long term shots also have a period of significant spike of high T which ends up with more conversion to E2 which kills a lot of the effectiveness of the T. For shots, most here prefer weekly shots of about 100mg. It's more even with less E2 problems. On Thu, 01 Feb 2007 14:11:48 -0000, you wrote: >Hi All, > >I went to see a new endo today. Haven't seen one in months! She >introduced me to Nebido. I came home and googled it. Haven't seen >much. It pretty sounds like other testosterone injections ,just last much >longer. So I'd like hear opinions of those who have tried it. The side >effects and stuff. > >I've been using testostoerone pellets for a year and a half now. I must >say, despite the pain, it's the best T replacement for me. I've tried >injections and gel. They are not as stable. Libido and energy are not as >high. Worst problem was gynecomastia. Others are acne, hair growth, >water retention, etc. > >Anyway, I'd like to know if Nebido has side effects like that. If it really >slowly releases testosterone(for 3 months) without upping estrogen, >then I would very much like to give it a try. > >Also, I saw something about Stiant SR. How does it work? You have to >stuck it in your mouth for 12 hours a time? Or it dissolves? I've never >heard about it. > >Or if there's any new testosterone replacements, please enlighten me. I >have not been active for so long. > >Any input will be highly appreciate it. >Thank you very very much. > >Pravit >BTW, has there been any new ED drug? I use Viagra and Cialis. They >work well for me. ----- " Anyone who has the power to make you believe absurdities has the power to make you commit atrocities. " - Voltaire Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2007 Report Share Posted February 1, 2007 Nebido is simply testosterone undecanoate in a huge 1000mg injection. Testosterone undecanoate is cheap, it requires minimal administration from the point of view of the physician and maintenance is assured by the longevity of the injection. Oh and it is crap- in that it fails to work for many people. Even though undecanoate has a very low conversion rate to estradiol when given in such vast doses as is typical it still often results in a doubling of estradiol and resultant problems with E2. It also often results in a large rollercoaster effect and stabilizing the dose take a vast period of time- as in two years upwards. The perfect drug for a small minority of men and a LARGE majority of lazy ass doctors! P.S You get this drug and you find out its profile is great in that it only converts to E2 in small amount so do you say to yourself we can really help men here? No screw that you think I know lets put it in VAST doses so we can make life easier and cheaper for the physician….. > > >Hi All, > > > >I went to see a new endo today. Haven't seen one in months! She > >introduced me to Nebido. I came home and googled it. Haven't seen > >much. It pretty sounds like other testosterone injections ,just last much > >longer. So I'd like hear opinions of those who have tried it. The side > >effects and stuff. > > > >I've been using testostoerone pellets for a year and a half now. I must > >say, despite the pain, it's the best T replacement for me. I've tried > >injections and gel. They are not as stable. Libido and energy are not as > >high. Worst problem was gynecomastia. Others are acne, hair growth, > >water retention, etc. > > > >Anyway, I'd like to know if Nebido has side effects like that. If it really > >slowly releases testosterone(for 3 months) without upping estrogen, > >then I would very much like to give it a try. > > > >Also, I saw something about Stiant SR. How does it work? You have to > >stuck it in your mouth for 12 hours a time? Or it dissolves? I've never > >heard about it. > > > >Or if there's any new testosterone replacements, please enlighten me. I > >have not been active for so long. > > > >Any input will be highly appreciate it. > >Thank you very very much. > > > >Pravit > >BTW, has there been any new ED drug? I use Viagra and Cialis. They > >work well for me. > > ----- > " Anyone who has the power to make you believe absurdities has the > power to make you commit atrocities. " - Voltaire > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2007 Report Share Posted February 1, 2007 On Thu, 01 Feb 2007 20:02:38 -0000, you wrote: > >Nebido is simply testosterone undecanoate in a huge 1000mg injection. My understanding is there is a mix of carriers for differential time release over the length between injections. ----- " Anyone who has the power to make you believe absurdities has the power to make you commit atrocities. " - Voltaire Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2007 Report Share Posted February 1, 2007 On Thu, 01 Feb 2007 12:45:42 -0800, you wrote: >On Thu, 01 Feb 2007 20:02:38 -0000, you wrote: > >> >>Nebido is simply testosterone undecanoate in a huge 1000mg injection. > > >My understanding is there is a mix of carriers for differential time >release over the length between injections. Sorry - my bad. I was thinking of Sustanton. ----- " Anyone who has the power to make you believe absurdities has the power to make you commit atrocities. " - Voltaire Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2007 Report Share Posted February 1, 2007 To me looking at the research makes me suspect if they were to inject it every month or 3 weeks the levels would be far more stable. As it is the 3 month regimen is the roll coaster over three months instead of 2 weeks with T enathate. Part of the problem is treatment protocols suggested by the drug companies that suggest these overly long spans between shots in my opinion. First it is too much and then too little. > > > > >Hi All, > > > > > >I went to see a new endo today. Haven't seen one in months! She > > >introduced me to Nebido. I came home and googled it. Haven't seen > > >much. It pretty sounds like other testosterone injections ,just > last much > > >longer. So I'd like hear opinions of those who have tried it. The > side > > >effects and stuff. > > > > > >I've been using testostoerone pellets for a year and a half now. I > must > > >say, despite the pain, it's the best T replacement for me. I've > tried > > >injections and gel. They are not as stable. Libido and energy are > not as > > >high. Worst problem was gynecomastia. Others are acne, hair > growth, > > >water retention, etc. > > > > > >Anyway, I'd like to know if Nebido has side effects like that. If > it really > > >slowly releases testosterone(for 3 months) without upping > estrogen, > > >then I would very much like to give it a try. > > > > > >Also, I saw something about Stiant SR. How does it work? You have > to > > >stuck it in your mouth for 12 hours a time? Or it dissolves? I've > never > > >heard about it. > > > > > >Or if there's any new testosterone replacements, please enlighten > me. I > > >have not been active for so long. > > > > > >Any input will be highly appreciate it. > > >Thank you very very much. > > > > > >Pravit > > >BTW, has there been any new ED drug? I use Viagra and Cialis. They > > >work well for me. > > > > ----- > > " Anyone who has the power to make you believe absurdities has the > > power to make you commit atrocities. " - Voltaire > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 2, 2007 Report Share Posted February 2, 2007 You are so right man, I took Pantestone 8 pills a day thats 40mgX8 and had no results almost. It took Androgel to make things work good enough and that has only been 2 years :-( after 6 on Pantestone crap undecanoate. chis_az <chis_az@...> wrote: Nebido is simply testosterone undecanoate in a huge 1000mg injection. Testosterone undecanoate is cheap, it requires minimal administration from the point of view of the physician and maintenance is assured by the longevity of the injection. Oh and it is crap- in that it fails to work for many people. Even though undecanoate has a very low conversion rate to estradiol when given in such vast doses as is typical it still often results in a doubling of estradiol and resultant problems with E2. It also often results in a large rollercoaster effect and stabilizing the dose take a vast period of time- as in two years upwards. The perfect drug for a small minority of men and a LARGE majority of lazy ass doctors! P.S You get this drug and you find out its profile is great in that it only converts to E2 in small amount so do you say to yourself we can really help men here? No screw that you think I know lets put it in VAST doses so we can make life easier and cheaper for the physician….. > > >Hi All, > > > >I went to see a new endo today. Haven't seen one in months! She > >introduced me to Nebido. I came home and googled it. Haven't seen > >much. It pretty sounds like other testosterone injections ,just last much > >longer. So I'd like hear opinions of those who have tried it. The side > >effects and stuff. > > > >I've been using testostoerone pellets for a year and a half now. I must > >say, despite the pain, it's the best T replacement for me. I've tried > >injections and gel. They are not as stable. Libido and energy are not as > >high. Worst problem was gynecomastia. Others are acne, hair growth, > >water retention, etc. > > > >Anyway, I'd like to know if Nebido has side effects like that. If it really > >slowly releases testosterone(for 3 months) without upping estrogen, > >then I would very much like to give it a try. > > > >Also, I saw something about Stiant SR. How does it work? You have to > >stuck it in your mouth for 12 hours a time? Or it dissolves? I've never > >heard about it. > > > >Or if there's any new testosterone replacements, please enlighten me. I > >have not been active for so long. > > > >Any input will be highly appreciate it. > >Thank you very very much. > > > >Pravit > >BTW, has there been any new ED drug? I use Viagra and Cialis. They > >work well for me. > > ----- > " Anyone who has the power to make you believe absurdities has the > power to make you commit atrocities. " - Voltaire > --------------------------------- Have a burning question? Go to Answers and get answers from real people who know. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2008 Report Share Posted June 4, 2008 Too bad, I love this product. Hopefully it will get approved later UPDATE 1-Indevus testosterone drug hits safety snag, shrs crash Wed Jun 4, 2008 9:19am EDT (Adds details throughout, share movement) June 4 (Reuters) - Indevus Pharmaceuticals Inc (IDEV.O: Quote, Profile, Research) said U.S. health regulators would ask for more safety data before approving its injectable testosterone drug, Nebido, sending its shares crashing 68 percent. The decision on approval of the drug was set to be taken later this month, but will now be delayed by about two years as the company plans to conduct another safety study and re-apply for approval in around 18 months, which would be followed by six months of review. Indevus, which has not yet received a formal request for additional data from the U.S. Food and Drug Administration, had previously applied for approval in August last year. Nebido treats male hypogonadism, a disorder in which testicles do not produce enough of the male sex hormone testosterone. Indevus said FDA's concerns were related to a reaction immediately following injection of the drug, which could lead to coughing, shortness of breath, and in some cases dizziness, flushing or fainting. The company said it believes the concerns stem from the post-marketing adverse event reports of the 1000 mg, or 4ml, dose of the drug, sold in Europe by German company Bayer Schering Pharma AG (SCHG.DE: Quote, Profile, Research). Indevus owns the U.S. rights to Nebido. " We are very surprised and disappointed by the position the FDA is taking regarding the safety profile of Nebido given the large European experience. Rare coughing reactions have been well-described in the European product labeling of Nebido, " Indevus Chief Executive Glenn said in a statement. said the company will allocate resources to conduct the additional safety study. Shares of the Lexington, Massachusetts-based company fell to $1.31 before the bell. They closed at $4.10 Tuesday on Nasdaq. (Reporting by Varsha Tickoo in Bangalore; Editing by Himani Sarkar) Regards, Vergel powerusa dot org Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.