Guest guest Posted April 9, 2010 Report Share Posted April 9, 2010 <<I am getting contradictory results for cucurmin most say it nullifies the effect of chemo>> " curcumin inhibited camptothecin-, mechlorethamine-, and doxorubicin-induced apoptosis of...breast cancer " www.cancerres.aacrjournals.org/contents-by-date.0.shtml (abstract 62/13/3868) " Curcumin....can diminish the usefulness of certain...drugs " (Gammill, 10/12/03), such as cytoxan. " While curcumin is a SAPK inhibitor it does...things...beneficial during chemo...lowers NF-kappaB...an important factor in drug resistance [MDR] [www.denvernaturopathic.com/news/multidrugresistance.html]...At least...with doxorubicin, 5-FU, cisplatin and Paclitaxel....curcumin [made] myeloma...more sensitive to...Vincristine and melphalan....reduced drug resistance to Vincristine [in other types of cancer]....increased the effect doxorubicin, 5-FU and Paclitaxel in a dose dependent manner [in] prostate cancer....reduced...resistance to cisplatin [for] fibrosarcoma...elevated liver enzymes normalized....drug resistance in ovarian cancer...reduced....reduce IL-6....cancer cells resistant to doxorubicin were sensitized...after treatment with curcumin. I...encourage its use with prostate, ovarian and maybe other cancers. [May enhance effects of] Cisplatin, 5-FU, Vincristine and Paclitaxel....may be best used to sensitize cancer cells before chemo is begun " www.denvernaturopathic.com (Curcumin Update #2 12/14/03) Unless I had reason to believe that curcumin would interfere w/the SPECIFIC chemo regimen I was on, I would definitely use it in large amounts because it helps prevent MDR. Leonard Quote Link to comment Share on other sites More sharing options...
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