Guest guest Posted February 25, 2008 Report Share Posted February 25, 2008 Hi guys, Thanks for all the responses. I'll bring up the E2 issue with my urologist and ask for some numbers. FYI, I've been off of Clomid now since end of October and on Testim gel since end of November. The uncomfortable symptoms are the same in both cases. Also, from what I understand Clomid does not raise E2. I seem to recall a study of its effects in men citing that it keeps E2 on the low side. Mike > > > > > > > > Hi guys, > > > > > > > > It's been a while since I've posted. Long story short: went on > Clomid > > > > last summer after 3 blood tests on separate dates revealed low free > > > > testosterone (though low-normal total T - around 380). Clomid raised > > > > my free and total T levels but I felt like crap, very sleepy every > > > > day, depressed, irritable. There was some improvement in sexual side > > > > effects including morning erections and more reliable orgasms. > > > > > > > > Switched to TRT gel in November on the theory that maybe the Clomid > > > > was causing the issues. But here I am in late Feb after 3 months on > > > > TRT and the sleepiness and depression continue. It's very weird. I > > > > sometimes start the day feeling great, good mood, energetic. But by > > > > mid-afternoon it's like a switch goes off. > > > > > > > > Has anyone else experienced this? My doc said my E2 levels were very > > > > low while on Clomid (but I didn't get the exact reading). I'm > guessing > > > > they're higher now since I'm on Testim, but the same symptoms > > > > continue. Doc also ruled out infection and apnea as causes of the > > > fatigue. > > > > > > > > Can testosterone trigger or worsen depression? I'm pretty > disappointed > > > > since I was expecting to feel generally hornier and in a better mood > > > > more often than not. But instead, I'm marginally better in terms of > > > > sexual functioning but much more prone to depressed episodes and > mood > > > > swings. > > > > > > > > Any insights you could offer would be appreciated, especially if > > > > you've experienced this yourself. I've got a follow up with my > > > > urologist next month and am in contact with my primary care about > > > > continuing to rule out other stuff... > > > > > > > > Thanks, > > > > > > > > Mike > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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