Guest guest Posted September 15, 2008 Report Share Posted September 15, 2008 Ingrid: I notice that you said you take 6 mg LDN with the Prednisone. For most people upper dose is 4.5mg LDN. Do you take the 6 because you are taking the Prednisone? Did your doctor recommend that you take the 6 mg because you take the Prednisone? I have been taking 7.5 mg Pred. since the month of May when a tapering dose for poison ivy seemed to coincidentally help my depression. We didn't know why, but I wanted to try taking a small dose long term to see if it would continue to help. (It does, maybe a little, not much, but I'm still taking it.) Do you think the LDN works better in combination with Pred. if the LDN is higher dose? (I understand the Pred. counteracts LDN). Thanks for your thoughts. Beverly > > Hi , > she should use the transdermal cream, if you have the possibilities to get it from a pharmacy where you live.You could use from 3.0 mg to 4.5 mg, (even more during a flare). You may try out what's doses that is functioning on her. I have just had a Crohns flare, and I am not allowed to use medications that puts down my immune system. But my GI gives me prednisone (I have to use something, though)and I now use pred (10 mg) a day with LDN (6 mg) while flareing, and I will continue with this untill I find that all has calmed down. Many people in here avoid the use of all immune supressors and modulators. You should read Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 16, 2008 Report Share Posted September 16, 2008 Hi Beverly. Yes, I have chosen to take 6 mg while my Crohns is in a bad period. I take it with prednisone, despite the fact that some doctors and users in here say that they counteract. Lately we have learned in here that prednisone in smaller doses can be used with ldn, the reason is that when the pred dose is lower than 10 mg it won't supress the immune system as it does when you use more than 10 mg a day. Ldn has always been used at max dose 4.5 mg. Lately there has been adjustments also here. Some needs more, and the suggestions has been to try up to 10 mg ldn a day. We are different, and we may need or react different using ldn. Finding a perfect dose needs trials and errors, I am sure there are some people feeling best at doses lower than 3 mg, maybe down to 1 mg (3 mg has been the most common dose suggestions from this forum together with 4.5 mg.)... When I feel better and my Crohns has calmed down (has taken 30 days this time, compared to 3 months on pred alone) I go down to 4.5 mg ldn again and taper off pred. I will not say that this is right for you or others to do so, but I will advice you or other to find a perfect dose for yourself instead of giving up using ldn. It's to hope that trials will find out that different diseases needs different dosages, I guess there will be variations betw. both diseases and persons. I have not asked my doctor about using ldn and small doses with pred together, I have found the information in here. But I have told my doctor that I do.Good luck to you from Ingrid :-) [low dose naltrexone] Prednisone and LDNIngrid:I notice that you said you take 6 mg LDN with the Prednisone. For most people upper dose is 4.5mg LDN. Do you take the 6 because you are taking the Prednisone? Did your doctor recommend that you take the 6 mg because you take the Prednisone? I have been taking 7.5 mg Pred. since the month of May when a tapering dose for poison ivy seemed to coincidentally help my depression. We didn't know why, but I wanted to try taking a small dose long term to see if it would continue to help. (It does, maybe a little, not much, but I'm still taking it.) Do you think the LDN works better in combination with Pred. if the LDN is higher dose? (I understand the Pred. counteracts LDN). Thanks for your thoughts.Beverly>> Hi ,> she should use the transdermal cream, if you have the possibilities to get it from a pharmacy where you live.You could use from 3.0 mg to 4.5 mg, (even more during a flare). You may try out what's doses that is functioning on her. I have just had a Crohns flare, and I am not allowed to use medications that puts down my immune system. But my GI gives me prednisone (I have to use something, though)and I now use pred(10 mg) a day with LDN (6 mg) while flareing, and I will continue with this untill I find that all has calmed down. Many people in here avoid the use of all immune supressors and modulators. You should read ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2009 Report Share Posted April 10, 2009 You have addisons? Do you mean adrenal shutdown from the steroids or full blown addisons? If you have true addisons you couldn't survive without steroids as you are incapable of making your own. Im confused! Maz > > I am on 25?MGs. of Prednisone and I have started LDN once again after trying it unsuccesfully a year ago;?While on it I had a terrible Crohn's flare and had to Start Prednisone again. ?I know the advice says to get off of the Prednisone first, but I have become unable to taper off of Prednisone without flare-ups.? I am hoping that if I overlap these drugs, that at some point the LDN will be able to start it's job and I can get off of Prednisone.? I have been diagnosed with 's disease at this stage and need to get off of these steroids.? I controlled my disease very succesfully for years through diet...but this disease has morphed over the years.? SCD does not work for all and makes many ill as it did me.? I had much success identifing?food sensitivities and starting a food elemination/rotation diet.? ...and no SIMPLE sugars! > > Chip > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2009 Report Share Posted April 12, 2009 was very weak and ill when I was last tapered off of Prednisone...Lab results showed extremely low levels of cortisol. I as immediately put back on the steroids, and we are trying a very slow taper to see if we can "jump-start" the adrenals again. (I hope they come back!) Back on point...My fear regarding the LDN is that I may be blocking the anti-inflammatory benefit of the Prednisone while taking the LDN. Does anyone know if there is some kind of (dose dependant) antagonistic conflict while taking both drugs? (on 25 Mgs. Pred currently) (I am taking 4.5 LDN as well). Chip You have addisons? Do you mean adrenal shutdown from the steroids or full blown addisons? If you have true addisons you couldn't survive without steroids as you are incapable of making your own. Im confused! Maz > > I am on 25?MGs. of Prednisone and I have started LDN once again after trying it unsuccesfully a year ago;?While on it I had a terrible Crohn's flare and had to Start Prednisone again. ?I know the advice says to get off of the Prednisone first, but I have become unable to taper off of Prednisone without flare-ups.? I am hoping that if I overlap these drugs, that at some point the LDN will be able to start it's job and I can get off of Prednisone.? I have been diagnosed with 's disease at this stage and need to get off of these steroids.? I controlled my disease very succesfully for years through diet...but this disease has morphed over the years.? SCD does not work for all and makes many ill as it did me.? I had much success identifing?food sensitivities and starting a food elemination/rotation diet.? ...and no SIMPLE sugars! > > Chip Save money by eating out! Find great dining coupons in your area. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2009 Report Share Posted April 12, 2009 dr mccandless said it was ok to use 10 mg prednisone with ldn.my wife sit 2.5 years on 7,5 mg prednisone for the adrenal together with ldn and it goes good.if you have joints pain you might consider D-Phenylalanine to help with the pain.if you have high blood pressure you cannot use it.with low cortisol most of the time you have low blood pressure > > > > I am on 25?MGs. of Prednisone and I have started LDN once again after trying it unsuccesfully a year ago;?While on it I had a terrible Crohn's flare and had to Start Prednisone again. ?I know the advice says to get off of the Prednisone first, but I have become unable to taper off of Prednisone without flare-ups.? I am hoping that if I overlap these drugs, that at some point the LDN will be able to start it's job and I can get off of Prednisone.? I have been diagnosed with 's disease at this stage and need to get off of these steroids.? I controlled my disease very succesfully for years through diet...but this disease has morphed over the years.? SCD does not work for all and makes many ill as it did me.? I had much success identifing?food sensitivities and starting a food elemination/rotation diet.? ...and no SIMPLE sugars! > > > > Chip > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 13, 2009 Report Share Posted April 13, 2009 Hi Chip, sounds like you'll have to taper down very slowly. Alternate day dosing is sometimes easier (eg. 25mg then 22.5mg then 25mg). I'm not an MD but the prednisone will probably still suppress your immune system to the point that the LDN won't do a lot yet, but your endorphins can still build up from it and that might help the pain. They would also be already built up as you taper the steroids, so effective sooner. An experienced naturopath could help with restarting your adrenals also. Licorice is known for this but has many contraindications, including taking steroids. Use only under supervision. Maz Quote Link to comment Share on other sites More sharing options...
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